Protein Purification Scientist
2 weeks ago
Please note that this is a 1 year contract position.
- Role is 100% onsite, at least 4 days in the Lab
- Need a Bachelor's Degree in Science
- Experience with Gene Therapy would be extremely helpful
- Must have experience of Protein Purification or Antibody Purification
- Experience with Chromatography (IEX)
- GLP experience a HUGE plus
- Must have 2-3 years of experience
- Experience or knowledge of AKTA, PAGE, DLS/DSF
- Electronic Notebook experience a HUGE help
BSc with 2-3 years of experience needed.
This position in in the RNA, Gene Therapy and Delivery Department offers an exciting opportunity to help develop novel Gene Therapies for unmet medical needs. We are investigating the use of Adeno-Associated Virus (AAV) vectors to deliver therapeutic proteins to patients for disease prevention and treatment, especially for ophthalmological, neurological, and novel therapies for infectious disease
We are seeking a highly motivated scientist to join a group that is engineering recombinant TESSA adenoviral vectors- a new scalable platform for manufacturing AAV therapies. The successful scientist will purify and characterize viruses, providing data to advance lead candidates.
Primary Responsibilities
Small-scale adenovirus production in mammalian cell culture and virus purification by AKTA-based IEX chromatography.
Performing a range of viral titration and QC assays including ddPCR, viral potency measurements, PAGE/ agarose gel electrophoresis, western blotting, DLS/DSF, and ELISA.
The candidate is expected to work in a team environment as well as contributing individually to meet project timeline and objective.
Applicants must provide their phone number. Reference job number A4042.
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