Postdoctoral Researcher

Pancreatic Cancer Postdoctoral Researcher

The project focuses on Pancreatic Cancer RNA biology research investigating the function of post-transcriptional gene regulation in tumor growth, focusing on RNA-related structure-function modeling. To identify the pathophysiological mechanisms and therapeutic targets particular to Pancreatic Cancer, the lab combines animal models with pathological and immunological analyses, as well as cutting-edge technologies such as targeted gene expression studies and global gene expression profiling, such as RNAseq, single-cell RNA-seq, RIP-seq, spatial transcriptomics, proteomics, and metabolomics. The candidates will participate in one of our fascinating research projects and are anticipated to have training in biochemistry, molecular biology, and mouse genetics. They should also have strong interpersonal skills for teamwork.

A postdoctoral researcher in cancer research may perform a variety of duties, including:

• Research design

Design and conduct experiments, develops, adapts, and implements new research techniques and protocols. And work with the Principal Investigator (PI) to develop hypotheses

• Laboratory work

Perform routine and complex laboratory procedures, such as working with mice, and use molecular biology techniques

• Data analysis

Analyze, interpret, and summarize data, and keep detailed records of experiments

• Presentations

Participate in presentations and publications as an author or co-author, and present findings to the scientific community

• Collaboration

Collaborate with other lab members and group members on research projects, and mentor junior lab members

• Grant proposals

Assist with the preparation of grant proposals and use communication skills to present ideas to donors or academic officials. Not responsible for generating grant funds.

• Teaching

Teach techniques and train research staff

The expectation is that PostDocs will collaborate with the Bioinformatics team, Dr. Hingorani, and the Wetlab support team to drive deeper discussions and insights, accelerating therapeutic innovation and novel drug discovery, and greater efficiencies.

To Best gauge Candidates we anticipate that the following research paper will provide you with the details and insights which drive our scientific experimentation direction and focus every day:

This approach and much of the science underlying it can be best described in a recent Nature Cancer Review article by Dr. Hingorani entitled Epithelial and stromal co-evolution and complicity in pancreatic cancer

Cite: Hingorani, S.R. Epithelial and stromal co-evolution and complicity in pancreatic cancer. Nat Rev Cancer 23, 57–77 (2023).

Qualifications Requirements

Applicants must have obtained or will obtain PhD/MD or related degree by the start of hire.

Required application materials:

Statement of research (1-3 pages)

Statement of teaching/mentoring (no more than 1 page)

Writing samples

References (minimum of 3)

Preferred Requirements

Graduate-level certification in research methodology and/or health specialization highly preferred.

Prior training in molecular biology, mouse genetics and disease models. Significantly, the expertise in studying mRNA expression, subcellular fragmentation, and protein-protein, protein-RNA, and protein-DNA interactions are preferred.

Prior first author publications in peer-reviewed journals.

Highly motivated to pursue an independent career in translational biomedical research.

Excellent communication, time management, and teamwork skills.