Postdoctoral Researcher
1 month ago
Postdoctoral fellow position
to study the role of the ubiquitin-proteasome system (UPS) in antitumor immunity
The Marzio lab at Weill Cornell Medicine has an available position to hire a highly motivated, creative, and enthusiastic postdoctoral fellow. Located in the Department of Pathology and Laboratory Medicine at Weill Cornell Medicine, the Marzio Lab investigates how deregulation of the ubiquitin-proteasome system (UPS) promotes cancer progression, with a particular emphasis on the DNA damage response (DDR) and antitumor immunity. To address this question, we use multidisciplinary approaches including biochemistry, cell signaling, mouse models of tumorigenesis, and pharmacotherapy.
Position Summary
Applicants should have recently completed their graduate degree (PhD or MD/PhD) with a background in biochemistry, and/or molecular and cellular biology. The successful candidate will lead projects to elucidate the role of E3 ubiquitin ligases (E3s) in antitumor immunity and dissect the biochemical and molecular mechanisms that drives tumorigenesis via deregulation of the E3s activity. The primary responsibility will be to design and perform benchwork independently to build confidence-in-rationale for novel targets in immune-oncology area and publish results in international meeting and peer-reviewed journals. The postdoc will utilize a multidisciplinary approach that will leverage a broad spectrum of experimental systems and levels of resolution (atomic, molecular, network, cellular, tissue, and organismal). In addition, the successful candidate will be encouraged to develop their own research ideas along the lines of the research interest of the lab. You will join a vibrant and fun lab environment and be part of a multidisciplinary team in a stimulating academic setting, with plenty of resources for intellectual and career development, as well as strong mentoring.
Principal Responsibilities
Key responsibilities of this role include, but are not limited to:
· Independently design, develop and test biological hypotheses.
· Interrogate novel cellular and molecular biology.
· Work independently to execute hands-on experiments and analyze data.
· Publish research findings in top-tier publications.
· Effectively present data in internal and external meetings.
· Drive multiple exploratory projects, and work collaboratively with research associate and graduate students.
Education and Qualifications
Required
· Recent Ph.D. in molecular and cell biology, biochemistry, oncology, or a related field.
· Strong track record demonstrated in the context of driving target discovery and validation projects and reflected in a strong record of achievement in peer-reviewed publications (i.e., at least one first author publication).
· Strong hands-on expertise and solid skills in molecular/cell biology and biochemistry.
· Ability to work in a team environment, excellent data handling and recording skills as well as oral and written communication skills.
· Ability of trouble shooting and data analysis.
Preferred
Prior mouse handling experience and flow cytometry knowledge.
If you are a dynamic team member, curios thinker, and careful experimentalist please consider joining our team and email Dr. Antonio Marzio (anm4031@med.cornell.edu). Please also visit:
Diversity and Inclusion are a part of Cornell University's heritage. We are a recognized employer and educator valuing AA/EEO, Protected Veterans, and Individuals with Disabilities. We also recognize a lawful preference in employment practices for Native Americans living on or near Indian reservations. Cornell University embraces diversity and seeks candidates who will contribute to a climate that supports students, faculty, and staff of all identities and backgrounds. We strongly encourage individuals from underrepresented and/or marginalized identities to apply.
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