Senior Director, Clinical Research, Metabolism

3 days ago


Boston, United States Merck Sharp & Dohme (MSD) Full time

Job DescriptionOur company is a global health care leader with a diversified portfolio of prescription medicines, vaccines, and animal health products. Today, we are building a new kind of healthcare company – one that is ready to help create a healthier future for all of us. Our ability to excel depends on the integrity, knowledge, imagination, skill, diversity, and teamwork of an individual like you. To this end, we strive to create an environment of mutual respect, encouragement, and teamwork. As part of our global team, you’ll have the opportunity to collaborate with talented and dedicated colleagues while developing and expanding your career.The Senior Director (Senior Principal Scientist) has primary responsibility for the planning and directing clinical research activities within the Atherosclerosis and Metabolism therapeutic area, with a particular focus on obesity and obesity-related metabolic disorders. The Senior Director will manage the entire cycle of clinical development, including study design, placement, monitoring, analysis, regulatory reporting, and publication.Specifically, the Senior Director may be responsible for Evaluating pre-clinical and translational work for the purpose of generating early clinical development plan and Investigational new drug applicationsDeveloping clinical development strategies for investigational or marketed drugsPlanning clinical trials (design, operational plans, settings) based on these clinical development strategiesMonitoring and managing the conduct of ongoing or new clinical trials for investigational or marketed drugsAnalyzing and summarizing clinical findings from studies to support decisions regarding safety and efficacy as well as new drug applications, clinical study reports, or publication; andParticipating in internal and joint internal/external research project teams relevant to the development of new compounds, and the further study of marketed compounds.In executing these duties, the Senior Director may:Supervise the activities of Clinical Scientists in the execution of clinical studiesWork closely with a cross-functional group of experts in commercialization, regulatory affairs, statistics, and manufacturing to manage clinical development projectsObtain internal and external expert opinion on scientific questions relevant to areas of responsibility.The Senior Director is responsible for maintaining a strong scientific fund of knowledge byMaintaining awareness of scientific developments within one’s area of expertise, in terms of new scientific findings and research methodologiesIdentifying scientifically and operationally strong investigators who can assist in the development of our company's investigational and marketed drugsEstablishing communications with prominent clinical investigators in their particular fields of interest, particularly those who would be willing and able to assist in the evaluation of our company's drugs; andAttending appropriate scientific meetings to maintain one’s competency and awareness of research activities in areas of responsibility.To accomplish these goals, the Senior Director mayAuthor detailed development documents, presentations, budgets, and position papers for internal and external audiencesFacilitate collaborations with external researchers around the world; andTravel on company business about 20% of the time to manage future or ongoing clinical research projects.Qualifications:Education• M.D or M.D./Ph.D.Required• Demonstrated record of scientific scholarship and achievement• Experience in clinical medicine and background in biomedical research• Strong interpersonal skills, as well as the ability to function in a team environmentPreferred• Minimum of 3 years of clinical medicine experience• Minimum of 3 years of industry experience in drug development or biomedical research experience in academia• Board Certification in Endocrinology & Metabolism or Obesity Medicine • Prior specific experience in clinical research and prior publicationCurrent Employees apply HERECurrent Contingent Workers apply HEREUS and Puerto Rico Residents Only:Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.We are an Equal Opportunity Employer, committed to fostering an inclusive and diverse workplace.  All qualified applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status, or other applicable legally protected characteristics.  For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:EEOC Know Your RightsEEOC GINA Supplement​Pay Transparency NondiscriminationWe are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively. Learn more about your rights, including under California, Colorado and other US State ActsU.S. Hybrid Work ModelEffective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”.The Company is required to provide a reasonable estimate of the salary range for this job in certain states and cities within the United States. Final determinations with respect to salary will take into account a number of factors, which may include, but not be limited to the primary work location and the chosen candidate’s relevant skills, experience, and education.Expected US salary range:$268,500.00 - $422,700.00Available benefits include bonus eligibility, long term incentive if applicable, health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and sick days. A summary of benefits is listed here.San Francisco Residents Only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance OrdinanceLos Angeles Residents Only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring OrdinanceSearch Firm Representatives Please Read Carefully Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company.  No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails. Employee Status: RegularRelocation:VISA Sponsorship:Travel Requirements:Flexible Work Arrangements:HybridShift:Valid Driving License:Hazardous Material(s):Job Posting End Date:01/24/2025*A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date. SummaryLocation: USA - New Jersey - Rahway; USA - Massachusetts - Boston (MA Parcel B Laboratory); USA - Pennsylvania - North Wales (Upper Gwynedd)Type: Full time



  • Boston, United States AstraZeneca Full time

    Do you have expertise and scientific reputation in the Cardiovascular, Renal, Metabolic Diseases research area? Are you excited by a role where you will provide global scientific leadership within your area of expertise to accelerate innovative science and turn ideas into life changing medicines? Would you like to apply your expertise in a company where we...


  • Boston, United States Harvard University Full time

    Assistant Professor, Department of Molecular Metabolism Title Assistant Professor, Department of Molecular Metabolism School School Harvard T.H. Chan School of Public Health Department/Area Department/Area Investigations of metabolic alterations underlying the most important, non-communicable diseases affecting human health, including metabolic diseases,...


  • Boston, United States Veranex Full time

    About This Role:Veranex has an exciting opportunity to join our team as a Director or Senior Director of Clinical Affairs. You will be part of a team working to improve lives globally through medical technology innovation. The Director of Senior Director of Clinical Affairs provides leadership and strategic business support to clinical operations staff....


  • Boston, United States F. Hoffmann-La Roche AG Full time

    Medical Director, Product Development, Cardiovascular MetabolicWe advance science so that we all have more time with the people we love.The OpportunityRoche’s Clinical Development organization is structured by therapeutic area and is responsible for developing and executing the late development (Phase II – III) clinical strategies and plans that deliver...


  • Boston, United States Veranex, Inc. Full time

    Veranex is the leading service provider for medtech companies. Our global team of experts help clients anticipate challenges and find solutions throughout the development and commercial lifecycle. Together, we accelerate new technologies to market and improve patient outcomes.About This Role:Veranex has an exciting opportunity to join our team as a Director...


  • Boston, United States Genentech Full time

    The Position Senior Pipeline Medical Science Liaison; Cardiovascular Metabolic Disease - Northeast Region The Opportunity The Senior Therapeutic Area Medical Science Liaison (TA MSL) is a credible scientific partner responsible for providing clinical and health economic information related to disease states and the appropriate utilization of Genentech...


  • Boston, United States EPM Scientific - Phaidon International Full time

    Title: Director of Clinical Operations, Greater Boston Area, HybridSalary: $220,000-$250,000Company Summary: We're partnering with a biotechnology firm focused on developing innovative therapeutics to address metabolic disorders, particularly type 2 diabetes and obesity. At the forefront of their research is a novel GLP-1 receptor agonist aimed at enhancing...


  • Boston, United States Cardiovascular Clinical Sciences Full time

    Boston Area Based, a full-time, hybrid position.CCS is seeking a highly motivated, self-driven Core Lab Clinical Research Project Coordinator to work in a fast-paced clinical research core lab environment. This role is responsible for the management of clinical imaging data (e.g. PET, CT, Echo, and Hemodynamic tracing) for clinical research trials,...


  • Boston, United States Berklee College of Music Full time

    Senior Director of Enrollment Research and AnalyticsApply locations Berklee College of Music - Boston time type Full time posted on Posted 4 Days Ago job requisition id R0009266Job Description:The Senior Director of Enrollment Research and Analytics leads, develops, and implements a strategic enrollment research and analytics plan to inform the setting and...


  • Boston, United States Genentech Full time

    The PositionSenior Pipeline Medical Science Liaison; Cardiovascular Metabolic Disease - Northeast RegionThe OpportunityThe Senior Therapeutic Area Medical Science Liaison (TA MSL) is a credible scientific partner responsible for providing clinical and health economic information related to disease states and the appropriate utilization of Genentech medicines...


  • Boston, United States Berklee College of Music Full time

    Job Description:The Senior Director of Enrollment Research and Analytics leads, develops, and implements a strategic enrollment research and analytics plan to inform the setting and achievement of goals, priorities, and strategies for student enrollment, engagement, and success across the entire student lifecycle. This hands-on position will lead the...


  • Boston, United States Entrada Therapeutics Full time

    The OrganizationWhat's happening at Entrada Therapeutics? Entrada is a clinical-stage biopharmaceutical company aiming to transform the lives of patients by establishing a new class of medicines that engage intracellular targets that have long been considered inaccessible.Our Endosomal Escape Vehicle (EEV)-therapeutics are designed to enable the efficient...


  • Boston, United States Entrada Therapeutics Full time

    The OrganizationWhat's happening at Entrada Therapeutics? Entrada is a clinical-stage biopharmaceutical company aiming to transform the lives of patients by establishing a new class of medicines that engage intracellular targets that have long been considered inaccessible.Our Endosomal Escape Vehicle (EEV)-therapeutics are designed to enable the efficient...


  • Boston, MA, United States Genentech Full time

    The PositionSenior Pipeline Medical Science Liaison; Cardiovascular Metabolic Disease - Northeast RegionThe OpportunityThe Senior Therapeutic Area Medical Science Liaison (TA MSL) is a credible scientific partner responsible for providing clinical and health economic information related to disease states and the appropriate utilization of Genentech medicines...


  • Boston, United States Leading Age Full time

    This is what you will do:The Global Medical Director will lead and contribute to the development and execution of the strategy in Bone Metabolism by providing strong scientific and medical expertise with an in-depth understanding of the disease area and unmet medical needs, consistent with the GMA’s mission to maximize patient outcomes and advance the...


  • Boston, United States Takeda Pharmaceutical Full time

    By clicking the "Apply" button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda's Privacy Notice and Terms of Use . I further attest that all information I submit in my employment application is true to the best of my knowledge. Job...


  • Boston, United States Takeda Pharmaceutical Full time

    By clicking the "Apply" button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda's Privacy Notice and Terms of Use . I further attest that all information I submit in my employment application is true to the best of my knowledge. Job...


  • Boston, United States Seaport Therapeutics Full time

    Senior Director, Investor Relations Seaport Therapeutics is seeking a Senior Director of Investor Relations (IR). This role will play a pivotal role in developing and executing Seaport’s overall investor relations strategy to effectively communicate Seaport’s value proposition, program progress, and company plans to the investment community. This role...


  • Boston, United States Dana-Farber Cancer Institute Full time

    THE DANA-FARBER CANCER INSTITUTE (DFCI) is seeking a visionary leader to join our team as the Senior Director of Product and Technology, serving our esteemed research community.This pivotal role reports directly to the Vice President (VP) of Research Informatics Operations (RIO) and plays a critical role in the development, implementation, and continuous...


  • Boston, United States Vertex Pharmaceuticals Full time

    Clinical Development Senior Medical Director, Inflammation page is loadedClinical Development Senior Medical Director, InflammationApply locations Boston, MA time type Full time posted on Posted 12 Days Ago job requisition id REQ-23325Job DescriptionGeneral Summary:Vertex is seeking an experienced Senior Medical Director for a leadership role in Inflammation...