Senior Research Associate-DMPK

4 weeks ago

Redwood City, United States Planet Pharma Full time

6-month contract to hire

Onsite only


Our client is seeking a highly motivated individual at Sr. Research Associate to Associate Scientist level (actual title pending on the candidate’s experiences) within the NDCP function (Non-clinical Development and Clinical Pharmacology). This role will serve as a key contributor in DMPK laboratory conducting LC-MS based quantitative bioanalysis. This position is for a temporary contractor with potential to convert to a full-time position.

The Opportunity:

  • Develop LC-MS/MS methods and analyze in vitro and in vivo samples to support ADME, pharmacokinetic, and toxicokinetic studies.
  • Perform data analysis, provide reports of experimental results, and upload data to electronic system and electronic notebook.
  • Conduct in vitro metabolic stability studies in bio-matrices, including hepatocytes, microsomes, blood, plasma, etc.
  • Perform in vitro ADME/DMPK assays, such as CYP inhibition, metabolic profiling, etc.
  • Assist in the operation, maintenance and troubleshooting of LC-MS/MS instrument.

Required Skills, Experience and Education:

  • Bachelor or master degree in Pharmaceutical Sciences or a related scientific discipline, with 3+ years of industry experiences.
  • Hands-on experiences in operating and maintaining an LC-MS/MS system
  • Hands-on experiences in LC-MS/MS method development and bioanalytical analysis
  • Knowledge of biological sample preparation and extraction techniques for downstream LC-MS/MS analysis
  • Hands-on experience in HPLC/UPLC method development
  • Ability to conduct multiple laboratory and project tasks efficiently
  • Ability to work in a team-oriented environment with flexibility
  • Highly organized, detail-oriented, excellent record keeping skills, and adapt to a dynamic and fast paced environment

Preferred Skills, Experience and Education:

  • Previous hands-on experience in SCIEX QTRAP and/or Thermo Q Exactive mass spectrometers
  • Working experience in DMPK lab

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