Scientist III

1 week ago

Alameda, United States TotalMed, Inc. Full time

Job Title - Temporary Scientist III

Job Location - Alameda, California

Pay: $50 top $64 an Hour


We are seeking a temporary, knowledgeable, self-motivated scientist to provide Antibody Drug Conjugate Bioconjugation and Chemistry support for the advancement of the ADC. The successful candidate must have strong chemistry and/or bioconjugation background as they will temporarily support discovery research and early process development activities for ongoing and new ADC projects.


ESSENTIAL DUTIES AND RESPONSIBILITIES:


  • Conduct hands-on laboratories studies to support ADCs and bioconjugates.
  • Provides chemistry and bioconjugation expertise for state-of-the-art ADC technologies including linkers, payloads, novel conjugation methods, analytical assessments and testing and bring novel ideas to POC.
  • Assist in chemical synthesis discussion, planning and execution.
  • Critical scientific/technical data analysis, interpretation of experiments and report writing.
  • Effectively communicate scientific concepts, findings, and interpretation to multi-disciplinary teams.
  • Follows company intellectual property and compliance policies and practices.
  • Complies with company health and safety policies and general laboratory practices.

EDUCATION/EXPERIENCE/SKILLS:

Education:

  • PhD in Chemistry or a closely related field and a minimum of three (3) years of related experience; or,
  • MS/MA in Chemistry or a closely related field and a minimum of seven (7) years of related experience; or,
  • BS/BA in Chemistry or a closely related field and a minimum of nine (9) years of related experience; or,
  • Equivalent combination of education and experience.

Experience:

  • Strong scientific understanding of chemistry, mechanism of action of cytotoxins and ADCs, and pharmacology studies in discovery of ADCs.
  • Hands on laboratory experience in bioconjugate research including critical reagent generation, identification, and optimization of bioconjugates, material production, purification, analytics, and characterization.
  • Experience in various aspects of small molecule chemical synthesis is preferred.
  • Demonstrated drive for rigorous scientific excellence. Ability to think critically and creatively to identify and solve scientific problems.

Knowledge/Skills/Abilities:

  • Knowledge of state of the art in different aspects of ADC research including conjugation technologies, linkers, and payloads.
  • Working knowledge of bioconjugation platforms, applications, and development.
  • Good working knowledge in analytical techniques including NMR, HPLC, and LCMS.
  • Ability to work independently, excellent time management and organization skills to manage multiple projects simultaneously.
  • Excellent written, oral, and interpersonal communication skills.
  • A strong team player.
  • Good tracking record and report writing.

JOB COMPLEXITY:

  • Works on extremely complex problems where analysis of situations or data requires an evaluation of intangible variables.
  • Exercises independent judgment in developing methods, techniques, and evaluation criteria for obtaining results.
  • Uses professional concepts in accordance with company objectives to solve complex problems in creative and effective ways.

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