Biology Scientist
2 weeks ago
Job Description
We are seeking a Scientist / Senior Scientist within the Biology Group in the Department of Research & Operation at our US site, Redwood Shores, California. In this role, you will be responsible for developing and executing assays that support screening, mechanism of action, translational relevance and/or biomarker identification for several programs focused on targeting myeloid cells for cancer immunotherapy.
Job Duties:
- Execute standard immunological assays (cell proliferation, cytokine analysis, phenotyping) using a variety of methods (plate-based assays, ELISA, flow cytometry, cell reporter assays)
- Creatively adapt standard assays or develop novel assays to test the unique biology of our platform
- Isolate and analyze cell subsets of interest from various tissues or mixed cell suspensions
- Support PK/PD and biomarker analysis as needed
- Present data at regular group meetings and recommend next steps
- Document research activities and findings in electronic laboratory notebook and reagent registries in keeping with the highest industry standards
- Exhibit excellent analytical, organizational, communication, and time management skills
- Lab activities will be ~75% time
Required Experience/Qualifications
- BA/BS or equivalent in biology, immunology, or a related discipline with 4+ years of relevant industry or academic research experience; MS degree or equivalent in biology, immunology, or a related discipline and 2+ years of experience conducting original research
- Deep understanding of immunology.
- Experience developing immune assays and working with primary immune cells (B, T, myeloid and NK) is required
- Proficiency in development of multi-parameter flow cytometry panels, analysis of immune cell function, and immune cell isolation.
- Skilled in the development of assays such as binding, internalization and/or various immunoassays to assess complex biology
- Excellent communication and interpersonal skills, enthusiasm and curiosity in science, and the ability to thrive in a dynamic cross-functional environment
- Experience with drug discovery and/or early development
- Experience with bioinformatics/computational biology tools would be a plus
Skills
• Excellent laboratory skills
• Excellent data analysis and organizational skills
• Excellent communication skills
• Ability to work independently and as part of a team
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