NMR Spectroscopist Chemist

Job description

Porton Pharma Solutions Ltd. is a leading global provider of comprehensive process R&D and manufacturing services to the pharmaceutical industry. We specialize in offering end-to-end solutions for small molecule APIs, dosage forms, and biologics. With a focus on innovation and customer satisfaction, we are committed to delivering high-quality products and services that meet the industry's evolving needs. Our experienced team of experts works tirelessly to ensure every project is completed on time, within budget, and to the highest possible standards. Whether you need support with drug development, manufacturing, or regulatory compliance, Porton Pharma Solutions Ltd. has the expertise and capabilities to help you achieve your goals.

J-STAR Research, Inc. is a subsidiary of Porton that specializes in providing contract chemistry services to the biopharmaceutical and biotechnology industry. Our primary focus is resolving intricate chemistry problems relating to Active Pharmaceutical Ingredients and Intermediates in the preclinical and clinical development phases. We are adept in synthetic chemistry and process research services, which include Process Chemistry, Quality Control, Good Manufacturing Practice, Quality Assurance, Crystallization Research and Development, Solid Form and Polymorph Screening, Catalysis Screening and Enabling Technology, High Potent Compound Handling (HPAPI), Impurity Isolation and Structural Elucidation, and Preformulation and Formulation Research and Development.

At J-Star, there are 5 NMR systems including one 500 MHz H/C/N Cryoprobe as well as two 400 MHz Bruker systems with multiple-nuclear and variable temperature capabilities. We are hiring an NMR Spectroscopist to support project team decisions and improve the speedy delivery of API for our clients.

Location: Cranbury and South Plainfield, NJ

Responsibilities:

• General maintenance and buildout of NMR facility.
• Ability to independently troubleshoot issues with NMR instrumentation.
• Structural elucidation of small molecule drug substances, intermediates, and starting materials.
• Identification and structure elucidation of related impurities/degradants from API synthesis, fate and purge, and stress degradation studies.
• Excellent oral and written communication skills in explaining the NMR data for structure elucidation.
• Good teamwork skills.

Requirement Qualifications:

• Ph.D. with 5+ years or MS with 10+ years of post-graduate, industrial or academic experience in small molecule NMR data collection and interpretation.
• Major in Organic/Physical Chemistry, Pharmaceutical Sciences, Physics, or related field.
• Experience with troubleshooting NMR hardware and software (Bruker and Varian) including magnets, consoles, conventional and cryo-probes, autosamplers and workstations (Windows and Linux).
• Evidence of creative application of NMR techniques to problems of pharmaceutical interest.
• Solid understanding and application of NMR theory to solve chemical structures and interactions of small molecules.
• Be part of a collaborative team of highly skilled chemists to solve chemical structures using 1D (1H, 13C, 19F, 15N, etc.) and 2D (COSY, ROESY, HSQC, HMBC, TOCSY, etc.) multinuclear, solution-state NMR techniques on state-of-the-art, high-field NMRs (300-500 MHz) equipped with conventional and cryoprobe technology.

Job Type: Full-time

Benefits:

• 401(k)
• 401(k) matching
• Dental insurance
• Health insurance
• Health savings account
• Life insurance
• Paid time off
• Referral program
• Vision insurance

Schedule:

• 8 hour shift

Experience:

• NMR: 4 years (Required)
• Pharmaceutical industry: 5 years (Preferred)

Ability to Relocate:

• Cranbury and South Plainfield, NJ: Relocate before starting work (Required)

Work Location: In person