AstraZeneca - UVA Postdoctoral Research Associate - Cardiovascular Functional Genomics

7 months ago


Charlottesville, United States Commonwealth of Virginia Full time
The Miller Laboratory at the University of Virginia seeks a talented postdoctoral research associate with a background in a life sciences field to apply systems genomics approaches to investigate mechanisms of inherited cardiomyopathies. Available projects include the generation and computational analysis of single-nucleus (e.g., snATAC/snRNA-seq), and spatial (e.g., spatial transcriptomics, proteomics) omics datasets from healthy and diseased subjects of ancestrally diverse backgrounds. The candidate will also contribute to functional genomic screens to validate discoveries in vitro and in vivo. The overall goals of this work are to contextualize rare and common genetic variation associated with cardiovascular diseases to inform early-stage detection and prevention. There will also be opportunities to classify common disease subtypes using machine learning approaches and identify clinically relevant targets/biomarkers for myocardial diseases.

This unique position is funded for 3 years through a partnership with AstraZeneca (Gaithersburg, MD), where the candidate will be exposed to a dynamic cross-functional training environment. At UVA the candidate will have access to a broad range of population genetic and genomic datasets through large-scale consortia projects, high performance computing resources, and will be exposed to a stimulating, multi-disciplinary and inclusive environment in the Center for Public Health Genomics (CPHG). This work will involve close collaborations with AstraZeneca scientists to broaden training in both data science and translational cardiovascular fields.

Minimum Requirements:

Candidates must have a PhD in a life sciences or quantitative field (required in hand by appointment start date).

Preferred Qualifications:

Experience in statistics or genetics is desired, including proficiency in R, python (or other scripting languages). The successful candidate will also have a strong working knowledge of biomedical fields such as human genetics, molecular/cell biology, physiology etc. Excellent written and verbal communication skills are required, as is the ability to work in a cross-functional team.

As part of the AZ-UVA postdoc mentoring program, the candidate will be encouraged to generate impactful publications, present in national and international scientific meetings, as well as participate in AZ networking and career development events.

To learn more about the position and the research please contact Dr. Clint Miller,

This is a 12-month appointment with the possibility of renewal contingent upon satisfactory performance and the availability of funding. Salary is commensurate with education and experience.

This is an Exempt level, benefited position. For more information on the benefits available to postdoctoral associates at UVA, visit postdoc.virginia.edu and hr.virginia.edu/benefits .

This position will sponsor applicants for work visa who meet the qualifications.

This position will remain open until filled. The University will perform background checks on all new hires prior to employment. A completed pre-employment health screen is required for this position prior to employment.

Physical Demands :

This position can spend extensive periods of time standing and squatting while conducting experiments or caring for animals. Also requires keyboarding and other bench work and animal procedures requiring finer finger manipulation.

The University of Virginia is an equal opportunity/affirmative action employer. Women, minorities, veterans, and persons with disabilities are strongly encouraged to apply.

To Apply:

Please apply through Workday , and search for R0048824 . Internal applicants must apply through their UVA Workday profile by searching 'Find Jobs'. Complete an application online with the following documents:
CV
Cover letter
Contact information for 3 references

Upload all materials into the resume submission field, multiple documents can be submitted into this one field. Alternatively, merge all documents into one PDF for submission. Applications that do not contain all required documents will not receive full consideration.

For questions about the application process, please contact Yelena Markazyan, Academic Recruiter, ym3mm @virginia.edu .

This position is located in Charlottesville, VA. For more information about UVA and the Charlottesville community please see and

The University of Virginia, i ncluding the UVA Health System which represents the UVA Medical Center, Schools of Medicine and Nursing, UVA Physician’s Group and the Claude Moore Health Sciences Library, are fundamentally committed to the diversity of our faculty and staff. We believe diversity is excellence expressing itself through every person's perspectives and lived experiences. We are equal opportunity and affirmative action employers. All qualified applicants will receive consideration for employment without regard to age, color, disability, gender identity or expression, marital status, national or ethnic origin, political affiliation, race, religion, sex (including pregnancy), sexual orientation, veteran status, and family medical or genetic information.

  • Charlottesville, United States Commonwealth of Virginia Full time

    The laboratory of Chongzhi Zang at the Center for Public Health Genomics, University of Virginia (UVA) is looking to recruit a Postdoctoral Research Associate in the field of functional genomics and epigenomics. The research program in the lab focuses on developing computational methods for high-throughput genomics technologies and integrating computational...


  • Charlottesville, United States Commonwealth of Virginia Full time

    The Center for Public Health Genomics at the University of Virginia is seeking to fill a Postdoctoral Research Associate position focused on statistical analysis of high-throughput molecular ‘omics data sets for collaborative projects at the cutting edge of human genetics, genomics, and high-throughput molecular ‘omics research under the supervision of...


  • Charlottesville, United States Commonwealth of Virginia Full time

    The Department of Radiation Oncology seeks to hire a Research Associate to study the mechanisms of replication stress response. The Liu laboratory in the Department of Radiation Oncology studies the mechanisms of genome stability in Cancer and other genetic disorders by using DNA single molecular, replication fork proteomics, and high-through screening...


  • Charlottesville, United States Commonwealth of Virginia Full time

    The Miller Laboratory at the University of Virginia School of Medicine seeks a research scientist with a background in molecular biology or genetics to apply functional genomic analyses to investigate inherited vascular diseases and cardiomyopathies. Available projects include the application of single-nucleus (e.g., snATAC/snRNA-seq, snCUT&Tag) and spatial...


  • Charlottesville, Virginia, United States Commonwealth of Virginia Full time

    Research Associate Opportunity at the University of VirginiaWe are seeking a highly motivated Postdoctoral Research Fellow to join our team at the Robert M. Berne Cardiovascular Research Center (CVRC) at the University of Virginia (UVA) School of Medicine.About the RoleThe successful candidate will participate in a multiplicity of relevant lab projects and...


  • Charlottesville, United States Commonwealth of Virginia Full time

    The Miller Laboratory at the University of Virginia seeks a highly motivated Laboratory Specialist with a background in the life sciences (e.g. genetics, molecular biology, cell biology, developmental biology, engineering or similar fields) to investigate the genomic and epigenomic basis of inherited vascular diseases and cardiomyopathies. Our group has...


  • Charlottesville, United States Commonwealth of Virginia Full time

    The Agaisse Lab is advertising post-doctoral positions available for training in the field of bacterial pathogenesis. The Agaisse Lab studies the intracellular pathogen Shigella flexneri, which causes approximately 270 million cases of bacillary dysentery (blood in stool) worldwide every year, resulting in more than 200,000 deaths. A multi-disciplinary...


  • Charlottesville, United States Commonwealth of Virginia Full time

    The Robert M. Berne Cardiovascular Research Center (CVRC) is currently seeking a Research Associate to investigate the calcium signaling mechanisms and ion channels in systemic and pulmonary vasculature within the Sonkusare Laboratory. The Sonkusare Laboratory employs state-of-the-art calcium imaging, superresolution imaging, patch-clamp electrophysiology,...


  • Charlottesville, United States Commonwealth of Virginia Full time

    The Department of Radiation Oncology seeks to hire a Research Associate to study the role of the ubiquitin system in regulating cell cycle progression, genomic stability and cellular response to ionizing radiation. The incumbent will perform biochemical and genetic studies to identify novel ubiquitin ligases and deubiquitinases involved in the sensing and...


  • Charlottesville, United States Commonwealth of Virginia Full time

    The Guler Malaria Laboratory at the University of Virginia has an opening for a Postdoctoral Research Associate to investigate the genetic and metabolic mechanisms that allow malaria to adapt to and survive anti-malarial drug treatment. Currently in the lab, we are investigating: 1) cellular mechanisms that drive genetic change in malaria parasites...


  • Charlottesville, Virginia, United States State of Virginia Full time

    Job Opportunity at the University of VirginiaThe State of Virginia is seeking a highly skilled Director of Genetically Engineered Murine Model Core to join our esteemed institution. This prestigious position offers an exceptional opportunity for a molecular biologist with expertise in genome engineering to lead our research efforts.About the PositionThis...


  • Charlottesville, United States Commonwealth of Virginia Full time

    The Department of Public Health and Center for Public Health Genomics at the University of Virginia Precision Health Initiative is seeking highly qualified applicants for a one-yea r Postdoctoral Research Associate position, with the possibility of extension to three years, based on an annual basis, dependent upon satisfactory performance and the...


  • Charlottesville, United States Commonwealth of Virginia Full time

    The Center for Diabetes Technology (CDT) and the University of Virginia (UVA) School of Medicine invites applicants for multiple Postdoctoral Research Associates for their research team, focusing on highly complex technology, algorithm development and data management and analysis. CDT is a recognized world leader in the technological treatment of diabetes...


  • Charlottesville, Virginia, United States University of Virginia Full time

    The University of Virginia is seeking a highly skilled Genetic Engineer and Research Director to lead the Genetically Engineered Murine Model (GEMM) Core. This position offers a unique opportunity to work with a talented team of researchers and contribute to cutting-edge genetic engineering initiatives.Company OverviewThe University of Virginia is a leading...


  • Charlottesville, United States Commonwealth of Virginia Full time

    The laboratory of Chongzhi Zang at the Center for Public Health Genomics, University of Virginia (UVA) is seeking to fill multiple Postdoctoral Research Associate positions in the broad field of bioinformatics and computational biology. The research program in the lab focuses on developing computational methodologies and designing integrative data science...


  • Charlottesville, United States Commonwealth of Virginia Full time

    The University of Virginia School of Medicine Department of Family Medicine is seeking highly qualified applicants for a one-year Postdoctoral Research Associate position, with the possibility of extension to three years based on an annual basis dependent upon satisfactory performance and the availability of funding. This position is funded by the UVA...


  • Charlottesville, United States Commonwealth of Virginia Full time

    The Department of Pharmacology, at the University of Virginia School of Medicine, seeks Postdoctoral Research Associates to work in the laboratory of Dr. Shengyi Iris Sun. The focus of this lab position is to combine cutting-edge technologies to investigate the regulation of endoplasmic reticulum (ER) homeostasis and associated protein degradation in...


  • Charlottesville, Virginia, United States Commonwealth of Virginia Full time

    Postdoctoral Research Associate OpportunityThe University of Virginia seeks a highly motivated Postdoctoral Research Associate to join the School of Nursing's Eleanor Crowder Bjoring Center for Nursing Historical Inquiry. This two-year appointment is funded by the Mellon Foundation and UVA matching funds to advance research and teaching related to race,...


  • Charlottesville, United States Commonwealth of Virginia Full time

    The Environmental Institute (EI) at the University of Virginia (UVA) is seeking a postdoctoral Research Associate to join its Climate Fellows Postdoc Program. The selected candidate will work with an interdisciplinary team of faculty mentors and researchers to realize the goals of a project i nvestigating the u nderlying c auses of c limate- r elated d...

  • Research Associate

    7 months ago


    Charlottesville, United States Commonwealth of Virginia Full time

    The Wythe Lab has an open position for a postdoctoral research associate to manage research projects, train junior scientists, and help maintain a dynamic laboratory environment. We attack biological questions on multiple fronts, using gold standard genetic models-such as the mouse and zebrafish, cutting edge imaging techniques (lightsheet, micro-CT),...