Senior Scientist, Antibody Discovery Platform Development
4 weeks ago
Janssen Research & Development, L.L.C., a division of Johnson & Johnson's Family of Companies is recruiting for a
Senior Scientist, Antibody Discovery Platform Development located in Cambridge, MA.
At Janssen, we never stop working toward a future where disease is a thing of the past.
We're the Pharmaceutical Companies of Johnson & Johnson, and you can count on us to keep working tirelessly to make that future a reality for patients everywhere, by fighting sickness with science, improving access with ingenuity, and healing hopelessness with heart.
We focus on areas of medicine where we can make the biggest difference:Cardiovascular & Metabolism, Immunology, Infectious Diseases & Vaccines, Neuroscience, Oncology, and Pulmonary Arterial Hypertension
Visit us:
As a member of the In Vivo Antibody Discovery Group, you will be responsible for development and optimization of efficient antibody discovery platforms.
As part of platform development effort, you will lead and drive the analysis of antibody repertoire from immunized animals and from enriched CHO libraries.
Responsibilities
- Contribute to development and evaluation of emerging technologies and platforms for antibody discovery through repertoire analysis from immunized animals or CHO display library
- Lead antibody generation using CHO display platform to screen immune repertoire
- CHO display library preparation with targeted integration using CRISPR/Cas9 or RMCE
- Regular presentation of data in team meeting, effective communication and coordination of work in highly matrixed project team environment
- This will involve designing and implementing NGS experiments to generate sequence data to characterize the antibody repertoire at different stages of antibody discovery.
- In addition to your primary responsibilities related to repertoire analysis with NGS, you may also be involved in mouse genetic engineering to improve antibody discovery efficiency.
- This may involve techniques such as CRISPR/Cas9 gene editing to introduce specific mutations or modifications to the mouse genome.
- A strong understanding of B-cell isolation methods such as Hybridoma technology and primary B-cell sorting will also be important.
- This is a critical function in a multifaceted Biologics Discovery organization committed to bringing the next generation of biotherapeutic molecules to patients.
- We are looking for a motivated candidate with scientific and technical expertise who can collaborate across discovery areas to bring value to our portfolio of innovative drug concepts.
- Proficiency to lead within a highly coordinated, fast-paced environment will be a significant attribute.
- An additional knowledge base in the areas of oncology, immunology, infectious disease, or cardiovascular disease would be a plus. If this sounds like you, come join our team
-
Sr. Scientist
4 weeks ago
Cambridge, Massachusetts, United States Momatx Full timeSr. Scientist/Principal Scientist, Computational ChemistryUnlocking a new target class in drug discovery is no small task: it requires computation to transform data into insights; it requires scientific and technological excellence; it demands a culture of focus, resilience, creativity, and collaboration; and it requires youis looking to expand our expertise...
-
Sr. Scientist
4 weeks ago
Cambridge, Massachusetts, United States MOMA Therapeutics Full timeMOMA Therapeutics is looking for an experienced Sr. Scientist/Principal Scientist, Computational ChemistryUnlocking a new target class in drug discovery is no small task: it requires computation to transform data into insights; it requires scientific and technological excellence; it demands a culture of focus, resilience, creativity, and collaboration; and...
-
Cambridge, Massachusetts, United States MOMA Therapeutics Full timeMOMA Therapeutics is looking for an experienced Sr. Scientist/Principal Scientist, Computational Chemistry About MOMA TherapeuticsUnlocking a new target class in drug discovery is no small task: it requires computation to transform data into insights; it requires scientific and technological excellence; it demands a culture of focus, resilience, creativity,...
-
Senior Scientist, Medicinal Chemistry
1 month ago
Cambridge, Massachusetts, United States Relay Therapeutics Full timeWe are looking for a self-motivated, creative, and experienced medicinal chemist to join our team and help drive projects from lead generation through candidate selection in a fast-paced, highly collaborative environment.Be an integral part of a multi-disciplinary lead optimization team (alongside pharmacologists, computational chemists, biophysicists, and...
-
Principal Scientist
1 month ago
Cambridge, Massachusetts, United States Nuvalent Inc Full timeWe are seeking an entrepreneurial Medicinal Chemist with strong technical and problem-solving skills in organic and medicinal chemistry.The scientist in this position will work with the Nuvalent team, including the scientific founder, and will be responsible for leading medicinal chemistry efforts on at least one early-stage project operating under a...
-
Computational Medicinal Chemist
2 days ago
Cambridge, Massachusetts, United States Novartis Group Companies Full timeComputational Medicinal Chemist/Senior Expert Data ScienceJoin our vibrant and innovative Computer-Aided Drug Discovery (CADD) team in Cambridge, where we bring together diverse talents to redefine the way Biomedical Research discovery teams validate and develop new targets.We are a driving force behind drug discovery, and we are now eagerly searching for an...
-
Cambridge, Massachusetts, United States Beam Therapeutics Full timePosition OverviewWe are seeking a motivated Scientist/Sr. Scientist to join our Analytical Research and Development team and perform method development and qualification for lot release and characterization of cell and gene therapy products and critical materials. S/he will work with a Beam's Analytical Development team to enable the rapid advancement of...
-
Cambridge, Massachusetts, United States Sana Biotechnology Full timeAbout the roleSana Biotechnology is growing, and we are hiring new team members who believe in the potential of engineered cells as medicines, who are passionate about delivering the possible to patients, and who lead with the desire to work on novel ideas. Sana is involved in developing gene and cell therapeutics for the treatment of a broad range of...
-
Associate Scientist: Formulation Development
1 month ago
Cambridge, Massachusetts, United States Proclinical Full timeAssociate Scientist: Formulation Development - Contract - OnsiteProclinical Staffing is seeking an Associate Scientist: Formulation Development to join a cutting-edge pharmaceutical company. This is a contract role located in Cambridge MA.Skills & Requirements:0-2 years of hands-on experience in parenteral formulation and/or process developmentUnderstanding...
-
Information Architect
2 weeks ago
Cambridge, Massachusetts, United States UCB Full timeMake your mark for patientsTo strengthen our IT Early Solutions Information Architecture team, we are looking to fill the position of Information Architect based out of either our Boston R&D Hub or our location in Raleigh, NC. This is not a remote role. As an Information Architect, you will deliver innovative data management, integration, and streaming...
-
Associate Scientist
4 days ago
Cambridge, Massachusetts, United States Eli Lilly and Company Full timeAt Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities...
-
Clinical Development Scientist
2 days ago
Cambridge, Massachusetts, United States Philips Full timeJob TitleClinical Development Scientist (Cambridge, MA)Job DescriptionClinical Development Scientist (Cambridge, MA)The Clinical Development Lead will primarily focus on study design strategy for the development of clinical study protocols and support the clinical operations team with study execution. This person will apply epidemiology principles and...
-
Scientist, NGS Assay Development
2 days ago
Cambridge, Massachusetts, United States Sana Biotechnology Full timeAbout the role Sana Biotechnology is developing the next generation of gene and cell therapies, and we are looking for a highly motivated Scientist to join our Analytical Genomics group. As a Scientist, you will report to Director NGS Assay Development at Cambridge to develop and optimize standard and novel NGS-based assays for cell and gene therapy programs...
-
Scientist - In Vivo Surgical Associate
1 month ago
Cambridge, Massachusetts, United States Eli Lilly and Company Full timeAt Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities...
-
Senior Scientist, Computational Biology
2 days ago
Cambridge, Massachusetts, United States Sana Biotechnology Full timeAbout the roleThe Computational Biologist will work closely with scientists and other computational biologists to analyze NGS genomics data and develop bioinformatics methods to solve exciting and challenging problems in cell and gene therapy, immunology, and stem cell biology. You will develop workflows from raw sequencing data to variant calling and...
-
Associate In Vivo Scientist
1 month ago
Cambridge, Massachusetts, United States Eli Lilly and Company Full timeAt Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities...
-
Senior Research Scientist
4 days ago
Cambridge, Massachusetts, United States Kensho Technologies Full timeAbout Kensho:Kensho is a 120-person Machine Learning (ML) and Natural Language Processing (NLP) company, centered around providing cutting-edge solutions to meet the challenges of some of the largest and most successful businesses and institutions. We are owned by S&P Global and operate independently. Our toolkit illuminates insights by helping the world...
-
Associate Scientist
1 week ago
Cambridge, Massachusetts, United States Eli Lilly and Company Full timeAt Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities...
-
Associate Scientist
1 week ago
Cambridge, Massachusetts, United States findojobs Full timeFull job description At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to...
-
Senior Battery Design Engineer
19 hours ago
Cambridge, Massachusetts, United States 24M Technologies Full timeCompany Description24M Technologies answers the world's need for affordable energy storage by enabling a new, more cost-effective solution — SemiSolidTM lithium-ion technology. Our breakthrough manufacturing platform provides for low-cost, high energy density, safe and long-life storage for electric mobility, grid and other applications. Through strategic...