Staff Mechanical Engineer

3 weeks ago

Raleigh, North Carolina, United States GRAIL Inc Full time
Our mission is to detect cancer early, when it can be cured. We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative, safe, and effective technologies that can transform cancer care.

We are a healthcare company, pioneering new technologies to advance early cancer detection. We have built a multi-disciplinary organization of scientists, engineers, and physicians and we are using the power of next-generation sequencing (NGS), population-scale clinical studies, and state-of-the-art computer science and data science to overcome one of medicine's greatest challenges.

GRAIL is headquartered in Menlo Park, California, with locations in Washington, D.C., North Carolina, and the United Kingdom. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies.

For more information, please visit

GRAIL's R&D team is building innovative processes and automation systems that are capable of delivering tests at an unprecedented scale. We are seeking passionate and talented individuals to join us in realizing our mission, which has the potential to dramatically reduce the global burden of cancer.

The Senior/Staff Automation Engineer - Integration and Scale will join a cross-functional development team that includes automation, process, and software engineering, along with R&D scientists, and clinical operations personnel. This team is responsible for transitioning manual and semi-automated workflows to a new fully-automated robotics platform. This position will play a key role in tying together automated laboratory liquid handling systems, robotic workcell automation and robust industrial automation systems into a new NGS-based clinical diagnostic system capable of running millions of patient samples per year. The ideal candidate will be experienced in the integration of components and devices from a wide variety of vendors with custom-built software solutions.

Responsibilities; Develop, configure, program, and troubleshoot large scale automated solutions for novel NGS-based clinical diagnostic testing in a regulated environment.Analyze current workflows and develop scalable procedures while identifying new sets of automated equipment to deploy.Be a key contributor to internal cross-functional project teams to develop technical product and automated system requirements.Provide expertise as a conduit to external contractors, suppliers, and integrated system providers in the design of large scale automated solutions.Develop and document work under design control and quality management systems, policies and procedures.Perform research, development, verification and validation testing per project needs.Author, execute and document test plans and Standard Operating Procedures (SOPs) for automated workflows.Support and grow the automation needs of GRAIL's research teamsMonitor and evaluate new and emerging technologies in laboratory automation systemsManage complex bills of materials, inventory tracking, and purchase ordersDevelop relationships with equipment vendors and field service engineersEvaluate and recommend engineering changes to existing devices and equipment in order to improve reliability, manufacturability, serviceability, and decrease cost.
Preferred Qualifications;B.S. or M.S. in Engineering with preference for Mechanical, Electrical, Chemical, Controls, or Process Engineering or a related Science field with appropriate automation experience.Minimum of 5+ years (Senior); 7+ years (Staff) experience with automation systems and transferring complex workflows into a high-throughput operation. Preference given to experience from the life science industry, but relevant experience from other industries will be considered (e.g. manufacturing in the food & beverage, pharmaceutical, chemical, agricultural, automotive industries)Experience implementing robotic workcells, preferably in a laboratory automation environment.Proven track record leading complex automation projects involving internal and external teams.Demonstrated delivery of automated systems into production environments.Comfortable managing projects and relationships through 3rd party contractors.Proficient in SolidWorks 2020 or later Experience designing and prototyping parts/assemblies using CAD systemsExperience developing control systems using PLCs or other I/O infrastructure (e.g. Allen Bradley, Beckhoff, Siemens, Labview, Arduino, etc.)Experience developing HMI/SCADA systems ( e.g. Ignition, FactoryTalk, Wonderware, etc.) Hands on experience troubleshooting electro-mechanical systemsProven track record working with machine shops for prototyping and manufacture of custom designed parts (e.g. 3D printing, machining, injection molding, etc.)Familiarity with P&ID and electrical schematics Highly energetic and self-motivated. Able to work independently and as part of a team.Analytical, creative thinker, ability to solve problems.Effective organizational and time management skills.
Nice To Have; Experience working with a broad set of laboratory instruments and tools.Experience working in a regulated environment (CLIA / CAP / FDA / ISO).Experience in reagent manufacturing, ideally in a regulated environment (cGMP).Experience with C#, powershell, pythonExperience or knowledge of communications protocols such as OPC, ModbusKnowledge of GD&T as it applies to machined parts and assemblies
Based on the role, colleagues may be eligible to participate in an annual bonus plan tied to company and individual performance, or an incentive plan. We also offer a long-term incentive plan to align company and colleague success over time.

In addition, GRAIL offers a progressive benefit package, including flexible time-off, a 401k with a company match, and alongside our medical, dental, vision plans, carefully selected mindfulness offerings.

GRAIL is an Equal Employment Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status. We will reasonably accommodate all individuals with disabilities so that they can participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. GRAIL maintains a drug-free workplace.

  • Overhead Transmission Engineer

    2 months ago

    Raleigh, North Carolina, United States Kiewit Full time

    Requisition ID:Job Level: Mid Level Home District/Group: Kiewit Power Engineering Department: Design Engineering Market: Power Employment Type: Full Time Position Overview Kiewit Power Engineers has an immediate opening for a motivated Overhead Transmission Engineer to join our growing Power Delivery team As part of this team of highly specialized design...

  • Sheet Metal Foreman

    2 months ago

    Raleigh, North Carolina, United States MCI - Mechanical Contractors LLC Full time

    Position Title: Sheet Metal ForemanJob Type: Full Time, Non-ExemptLocation: Raleigh NCMCI seeks a Sheet Metal Foreman to supervise, coordinate, inspect, and perform the assembly, installation, and repair of components, subsystems, and systems for the sheet metal trade during the construction, tenant finish-out, or remodel of commercial buildings and...

  • Structural Engineer I

    10 hours ago

    Raleigh, North Carolina, United States Delta Oaks Group Full time

    SummaryDelta Oaks Group is seeking an individual to perform various structural engineering analysis and design services, as part of our Structural Engineering Department located in Raleigh, NC.Positional ResponsibilitiesUnder the supervision of Chief Structural Engineer, the selected individual will perform design, computations, and evaluations generally...

  • Structural Engineer II III

    8 hours ago

    Raleigh, North Carolina, United States Delta Oaks Group Full time

    SummaryDelta Oaks Group is seeking an individual to perform various structural engineering analysis and design services, as part of our Structural Engineering Department located in Raleigh, NC. The selected individual will perform various structural engineering design/analysis tasks as well as serve as the primary liaison to our infrastructure inspections...

  • Structural Engineer II

    8 hours ago

    Raleigh, North Carolina, United States Delta Oaks Group Full time

    SummaryDelta Oaks Group is seeking an individual to perform various structural engineering analysis and design services, as part of our Structural Engineering Department located in our Raleigh, NC office.Positional ResponsibilitiesUnder the supervision of Director – Structural Engineering, the selected individual will perform design, computations, and...

  • Process Automation Engineer

    1 month ago

    Raleigh, North Carolina, United States Automationtechies Full time

    Our client works within the life sciences industries integrating systems simple and complex to gather and analyze data for a better manufacturing experience. They invest in their team providing access to top-notch automation training and education that saves time, increases efficiency, and enhances workforce skills. They innovate, integrate and...

  • Senior Backend Engineer, Contract

    3 weeks ago

    Raleigh, North Carolina, United States Xsolla Full time

    We are looking for a Senior Backend Engineer to review, optimize and scale our backend systems. The consultant will be responsible for re-architecting our current backend to scale and perform, apply microservices and AI in the process of re-architecture, and ensure the system can handle increased loads efficiently. This role requires a deep understanding of...

  • Land Development Engineer

    2 months ago

    Raleigh, North Carolina, United States tapwage Full time

    OverviewABOUT THE POSITIONVHB's Raleigh, NC Office is seeking a Project Engineer or Project Manager to join our growing Land Development and Planning and Design team. This is an exciting opportunity to work within a dynamic team, across diverse disciplines, giving you exposure to a wide variety of projects in size and scope. Our past and present clients...

  • Civil Engineer III

    2 weeks ago

    Raleigh, North Carolina, United States Delta Oaks Group Full time

    Summary The selected individual will be responsible for leading various civil-site engineering and site planning tasks, including but not limited to jurisdictional zoning code research and interpretation, spatial infrastructure layout, grading plans, roadway plan and profile, utility layout and coordination, and erosion control typically associated with...

  • AE Project Engineer II

    4 weeks ago

    Raleigh, North Carolina, United States Delta Oaks Group Full time

    Summary Delta Oaks Group is seeking an individual to lead A&E projects in the telecom vertical. Typical responsibilities include but are not limited to design and production tasks as well as scoping, project management, client communication, and program management services associated with turnkey A&E projects in the telecommunications industry. This position...

  • Senior Software Quality Engineer

    2 months ago

    Raleigh, North Carolina, United States Red Hat Full time

    Senior Software Quality Engineer - OpenShift OCMJob SummaryThe Red Hat QE team is seeking people with a curious and innovative mindset, and diverse technical backgrounds. Automated testing, software development or devops, you can touch all of that in QE on the journey to make our software better.Find out more about what it is like to work in Red Hat QE...

  • Maintenance Engineer 3rd shift

    2 months ago

    Raleigh, North Carolina, United States SANINC Full time

    Location Type: Metal ManufacturingMetal Type: VariousMetal Shape: Full lineCompensation Range: $90K+ Minimum of 3+ years experience troubleshooting, and diagnosing mechanical, hydraulic, and pneumatic systems.Experience facilitating major repairs or rebuilds in a heavy metal industrial and manufacturing environment.Minimum of 3+ years experience analyzing...

  • Air Quality Scientist IV

    4 weeks ago

    Raleigh, North Carolina, United States AECOM Full time

    Job DescriptionAECOM is seeking a Measurements Scientist IV for employment in our Raleigh, NC office. In this role, you will perform scientific air pollution measurements requiring field application of standard EPA techniques and procedures.Responsibilities will include but may not be limited to the following:Manage field and office tasks on source emission...

  • AE Project Designer II

    4 weeks ago

    Raleigh, North Carolina, United States Delta Oaks Group Full time

    SummaryDelta Oaks Group is seeking an individual to lead A&E / Civil projects in the telecom and renewable energy vertical. Typical responsibilities include but are not limited to design and production tasks as well as scoping, project feasibility assessment, client and project stakeholder communication, and quality assurance/quality control plan review....

  • Sr. Manager, Development

    2 months ago

    Raleigh, North Carolina, United States Brookfield Asset Management Inc. Full time

    LocationRaleigh Westchase Blvd., Suite 150Business - Real EstateBrookfield Real Estate Group is one ofBrookfield's primary operating groups. The Real Estate Group is one of the world's largest investors in real estate, with a global portfolio that includes office, retail, multifamily, logistics, hospitality and alternative real estate assets on five...

  • Project Coordinator

    2 weeks ago

    Raleigh, North Carolina, United States Delta Oaks Group Full time

    SummaryDelta Oaks Group is seeking a candidate to coordinate multiple aspects of projects related to telecom engineering teams, including project set up, schedule coordination with subcontractors, tracking and maintaining subcontractor data. This position provides support to management and engineering staff as necessary to complete various services, ensuring...

  • Estimator - Raleigh, NC

    2 weeks ago

    Raleigh, North Carolina, United States OLDCASTLE INFRASTRUCTURE, INC. Full time

    Job ID: ExemptOldcastle InfrastructureTM , a CRH company, is the leading provider of utility infrastructure solutions for the water, energy, and communications markets throughout North America. We're more than just a manufacturer of precast concrete, polymer concrete, or plastic products. We're a trusted and strategic partner to engineers, contractors,...

  • Field Technician II

    2 weeks ago

    Raleigh, North Carolina, United States Gregory Poole Equipment Company Full time

    Field Technician II4807 Beryl Rd, Raleigh, NC 27606, USA Req #1313Thursday, July 18, 2024PRIMARY FUNCTIONThe primary function of this position is to independently troubleshoot, remove, install, replace, rebuild, repair, and test parts/equipment on construction equipment at an advanced level while working in the field.ESSENTIAL DUTIES: Check the equipment...

  • Substation Designer

    2 months ago

    Raleigh, North Carolina, United States Kiewit Full time

    Requisition ID:Job Level: Entry Level Home District/Group: Kiewit Power Engineering Department: Design Engineering Market: Power Employment Type: Full Time Position Overview We are currently looking for a motivated Substation Designer/Drafter to join our growing Substation and Transmission Line Design team in Raleigh, NC. As part of the team of highly...

  • Land Survey Crew Chief

    2 weeks ago

    Raleigh, North Carolina, United States Pennoni Full time

    Pennoni is a multidisciplinary consulting engineering firm founded more than five decades ago. We approach engineering challenges from a wider spectrum of angles than most, from land development to energy management. Our goal is to help communities and private sector clients alike navigate the ever-changing technological advancements available and learn how...