Sr. Research Scientist II
2 weeks ago
United States - California - Foster City
Gilead Sciences, Inc. is a research-based bio-pharmaceutical company that discovers, develops and commercializes innovative medicines in areas of unmet medical need. With each new discovery and investigational drug candidate, we seek to improve the care of patients living with life-threatening diseases around the world. Gilead's therapeutic areas of focus include HIV/AIDS, liver diseases, cancer and inflammation, and serious respiratory and cardiovascular conditions.
Making an impact on a global scale
Inclusion is one of the company's five core values. That's because we know that we are stronger and more innovative at Gilead when we are informed by a diverse set of backgrounds, experiences and points of view. Gilead Sciences is a biopharmaceutical company that discovers, develops and commercializes innovative therapeutics in areas of unmet medical need. The company's mission is to advance the care of patients suffering from life-threatening diseases worldwide.
When you join Gilead, you join our mission to change the world by enabling people to live healthier and more fulfilling lives. Come join a mission-driven bio-pharmaceutical organization that values inclusion and diversity, has a strong portfolio of products, and is constantly #CreatingPossible
For Current Gilead Employees and Contractors:
Please log onto your Internal Career Site to apply for this job.
At Gilead, we're creating a healthier world for all people. For more than 35 years, we've tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer - working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world's biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference.
Every member of Gilead's team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we're looking for the next wave of passionate and ambitious people ready to make a direct impact.
We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together.
Job Description
Job Description: Senior Research Scientist II (SRSII), Oncology, Biomarker Sciences & Diagnostics
The Biomarker Sciences Department is seeking an experienced Senior Research Scientist II to support Gilead's Oncology pipeline. The successful candidate will will work in a dynamic multidisciplinary matrixed team environment to generate and interpret data from translational and clinical studies, and be expected to lead and support biomarker subteams for late-stage or early development programs. This scientist will design biomarker experiments and provide biomarker expertise to discovery and development project teams to ensure access to state of the art thinking on appropriate biomarker and diagnostic technologies, including evaluation of their scientific basis and clinical applicability, the validation status and any technical or statistical issues related to the proposed biomarker assays. The scientist will provide input on clinical protocols and associated documents as well as participate in meetings with regulatory authorities. In addition, the scientist will direct the development, outsourcing and validation of clinically applicable biomarker assays (including pharmacodynamic, predictive, prognostic, and other biomarkers) and design, implement and oversee biomarker testing and data analysis together with the specific functional area representatives, including partnering with the diagnostic team. The successful candidate will lead cross functional teams to achieve these aims. Gilead Sciences Inc. is a highly matrixed organization and the ability to work effectively across these groups is a key attribute for this role. Experience in the analysis of multi-dimensional data sets and a strong understanding of mechanisms of immunology and a background in cancer cell signaling research and translational biology is highly desirable.
Responsibilities:
Lead cross-functional Biomarker Teams to define and execute biomarker/diagnostic development strategies to generate, analyze, and interpret data from clinical studiesDirect the development, outsourcing, and validation of clinically applicable biomarker assays including pharmacodynamic, predictive, prognostic, safety and other biomarkers for oncology programsIdentify, establish and oversee external collaborations with key opinion leaders, academic sites, and CROs to advance our understanding of disease pathways and prognostic/predictive biomarkersCollaborate with Research Biology, Clinical Development, Diagnostics, Bioinformatics and Biostatistics functions to create synergy in developing biomarker strategies and translational approachesWrite, review and coordinate biomarker plans in clinical trial protocols, regulatory documents and collaboration agreements.Must be able to work independently and effectively on multiple programs in a fast-paced matrixed environmentExcellent collaboration, communication, and interpersonal skills are required to engage and be productive within a high achieving team environment, with the ability to effectively organize and present plans and results at department, company, and/or project team meetings.Must be team and detail-oriented, motivated, and results focused.
Technical Skills:
Strong experimental background and experience in hypothesis-driven biological/translational research with demonstrated ability to execute well-designed experiments in tumor immunologyExperience planning and executing biomarker and diagnostic strategy, experimentation and testing in support of drug discovery and development, including analysis and interpretation of biomarker data in preclinical and clinical settingExperience authoring biomarker strategy documents, biomarker specific portions of clinical protocols and regulatory documentation. Experience in the analysis of multi-dimensional data sets including with genomic, epigenetic, gene expression, metabolomics, multiplexed protein detection or other related emerging platforms or data sets is desirable.Demonstrates technical proficiency, scientific creativity, collaboration with others and independent thought in suggesting biomarker and diagnostic strategies for immunology and/or oncology clinical developmentUnderstands the multidisciplinary functions involved in biomarker and diagnostics development.In-depth knowledge of biomarker discovery and development, assay development / validation, clinical discovery of biomarkers, MoA / translational research and companion diagnostics development.Understands the opportunities and challenges in implementing biomarker and diagnostic technologies in a preclinical and clinical setting, including understanding of drug discovery and development in both early and late-stage development and familiarity with the regulatory approval process.Proven track record in effectively applying original scientific thought to the development of project concepts or approaches for experimentation.Proven scientific/leadership expertise (working in teams, managing people/projects commensurate with level)Proven abilities to apply business acumen to strategic scientific projects.Results-oriented, independent self-starter who thrives working in a fast-paced dynamic environment.Demonstrated success in managing multiple projects.Has a strong track record of high-quality publications.Strong communication and organizational skills, with an ability to lead, influence, and motivate others.When needed, ability to travel.
Experience:
PhD and/or post-doctoral training in the area of immunology and/ or oncology or other related medical science field with a minimum of 5 years of directly relevant biotechnology or pharmaceutical industry experience (7+ years experience preferred). Candidate must be detail-oriented with excellent record keeping and organizational skills. Must be a highly flexible, results oriented, independent self-starter who enjoys working in a fast paced dynamic multi-disciplinary environment.
The salary range for this position is: $205, $266, Gilead considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans*.
For additional benefits information, visit:
* Eligible employees may participate in benefit plans, subject to the terms and conditions of the applicable plans.
For jobs in the United States:
As an equal opportunity employer, Gilead Sciences Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact for assistance.
For more information about equal employment opportunity protections, please view the 'Know Your Rights' poster.
NOTICE: EMPLOYEE POLYGRAPH PROTECTION ACT
YOUR RIGHTS UNDER THE FAMILY AND MEDICAL LEAVE ACT
PAY TRANSPARENCY NONDISCRIMINATION PROVISION
Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team.
Gilead provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion.
For Current Gilead Employees and Contractors:
Please log onto your Internal Career Site to apply for this job.
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