Scientist I or II

Description

The Separation Sciences group in Discovery Chemistry at our client in Boston, MA is seeking a candidate to join their team whose mission is to analyze and purify novel medicines prepared by their medicinal chemist colleagues. This laboratory-based role will support their high throughput purification workflows by monitoring and maintaining instrument performance, executing sample handling tasks, and managing chemicals and consumables.

Responsibilities

Upkeep of HPLC (high performance liquid chromatography), SFC (super-critical fluid chromatography), and automation instrumentation; including running and evaluating standards, preparing and filling solvents, and coordinating repairs with external partners.Operating automated weighing and liquid handling instrumentation.Coordinating the weighing, labeling, tracking, and returning of purified fractions.Initiating pre-purification and post-purification analysis of submitted samples by LCMS (liquid chromatography - mass spectrometry).Managing the ordering and stocking of chemicals and consumables.Authoring SOPs for routine laboratory upkeep tasks.QualificationsBachelor's or Master's degree in chemistry or a closely related fieldScientist 1: 0-1 years of experience with a Bachelor's degreeScientist 21-2 years of experience with a Bachelor's degree0-1 years of experience with a Master's degreeRequired Skills and ExperienceExperience working in a laboratory and safely handling chemicals and preparing buffers.Basic familiarity with laboratory equipment including HPLC, LCMS, and automation instruments.Daily use of Microsoft suite of applications (e.g., Word, PowerPoint, Excel, Teams).Effective organizational and multi-tasking skills with high attention to detail.Desired Skills and ExperienceExperience with the operation and troubleshooting of laboratory equipment including HPLC, LCMS, automated liquid handlers, automated weighing instruments, and centrifugal evaporators.Working knowledge of chromatography and mass spectrometry.Experience with LCMS instrument software including Waters MassLynx and Agilent Chemstation.Experience with writing and following SOPs for complex laboratory workflows.

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