Scientist, Electrophysiology

Job Description

Position Description:

The Neurophysiology Group within the Research and Development organization is searching for an experienced electrophysiologist to support novel drug discovery research in CNS disorders. This position will be part of a larger multidisciplinary team challenged with interrogating the pharmacological properties and synaptic mechanism(s) of action of compounds in a variety of neuronal systems. Individuals with exceptional neurophysiology experience are encouraged to apply. The ideal candidate will have neuroscience research experience employing a variety of in vitro/in vivo electrophysiology techniques including traditional whole-cell patch-clamp, extracellular field potential recordings, and qEEG. Additional computational or programming experience is also required. Highest priority will be given to candidates with a strong desire to be in the laboratory designing and conducting experiments to support discovery projects.

Responsibilities

Key Duties:

• Design, develop, and implement in vitro/in vivo electrophysiological protocols and assays.
• Engage in thorough analysis of data, generate summaries and interpretations of results, and present findings within the Neurophysiology Group, project teams, research department, and the greater Alkermes community.
• Explore and apply new models, methodologies, and technologies to expand the group capabilities and help drive programs forward.

Technical Skills:

• Possess broad knowledge base in neurobiology, neuropharmacology and neurophysiology (including synaptic function, neurocircuitry, or systems neuroscience).
• Proficient in in vitro electrophysiological techniques including whole-cell patch-clamp and extracellular field potential recordings from acute brain slice.
• Experience with in vivo electrophysiological techniques (qEEG) in freely moving rodents (primarily rats) and signal processing.
• Programming experience (i.e. Matlab, Python, etc.) is required.
• Experience with HTS electrophysiology platforms such as multielectrode array recording systems is beneficial.

Personal Skills:

• Must work well in a team environment and have excellent interpersonal skills.
• Well organized and able to multi-task projects/experiments.
• Outstanding personal initiative with the ability to take the lead, influence, and motivate others.
• Strong desire to explore innovative technologies and approaches.
• Flexibility to learn and take on new tasks when needed.
• Strong communication skills and ability to distill complex datasets into meaningful, actionable information.

Qualifications

Minimum Education and Experience:

• A Ph.D. in neuroscience, neurobiology, or related discipline or MS degree with 5+ years of equivalent experience or BS degree with 10+ years of equivalent experience is required.
• Experience in a biotechnology/pharmaceutical setting is preferred but not required

About Us

Why join Team Alkermes?

Alkermes applies its deep neuroscience expertise to develop medicines designed to help people living with complex and difficult-to-treat psychiatric and neurological disorders. A fully-integrated, global biopharmaceutical company, headquartered in Ireland with U.S. locations in Massachusetts and Ohio, we are committed to pursuing great science, driven by deep compassion to make a real impact in the lives of patients. Alkermes has a portfolio of proprietary commercial products for the treatment of alcohol dependence, opioid dependence, schizophrenia and bipolar I disorder, and a pipeline of clinical and preclinical candidates in development for various neurological disorders, including narcolepsy.

Beyond our important mission of developing medicines to address unmet patient needs, we actively seek to foster a culture of diversity, inclusion and belonging throughout our business. We strive to ensure that all voices are respected and valued, recognizing that our diversity of thought, background and perspective makes us stronger. We are proud to have been recognized as an employer of choice by many national organizations, including being certified as a Great Place to Work in the U.S. in 2024, honored as a Healthiest Employer in both Ohio and Massachusetts in 2023, a Best Place for Working Parents in 2023, and to have received the Bell Seal at the Platinum level for Workplace Mental Health by Mental Health America for three consecutive years

Alkermes, Inc. is an equal employment opportunity employer and does not discriminate against any qualified applicant or employee because of race, creed, color, age, national origin, ancestry, religion, gender, sexual orientation, gender expression and identity, disability, genetic information, veteran status, military status, application for military service or any other characteristic protected by local, state or federal law. Alkermes also complies with all work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Alkermes is an E-Verify employer.