Staff Automation Engineer

4 weeks ago


Raleigh, North Carolina, United States GRAIL, LLC Full time
GRAIL's R&D team is building innovative processes and automation systems that are capable of delivering tests at an unprecedented scale. We are seeking passionate and talented individuals to join us in realizing our mission, which has the potential to dramatically reduce the global burden of cancer.

The Senior/Staff Automation Engineer - Integration and Scale will join a cross-functional development team that includes automation, process, and software engineering, along with R&D scientists, and clinical operations personnel. This team is responsible for transitioning manual and semi-automated workflows to a new fully-automated robotics platform. This position will play a key role in tying together automated laboratory liquid handling systems, robotic workcell automation and robust industrial automation systems into a new NGS-based clinical diagnostic system capable of running millions of patient samples per year. The ideal candidate will be experienced in the integration of components and devices from a wide variety of vendors with custom-built software solutions.

Responsibilities; Develop, configure, program, and troubleshoot large scale automated solutions for novel NGS-based clinical diagnostic testing in a regulated environment.Analyze current workflows and develop scalable procedures while identifying new sets of automated equipment to deploy.Be a key contributor to internal cross-functional project teams to develop technical product and automated system requirements.Provide expertise as a conduit to external contractors, suppliers, and integrated system providers in the design of large scale automated solutions.Develop and document work under design control and quality management systems, policies and procedures.Perform research, development, verification and validation testing per project needs.Author, execute and document test plans and Standard Operating Procedures (SOPs) for automated workflows.Support and grow the automation needs of GRAIL's research teamsMonitor and evaluate new and emerging technologies in laboratory automation systemsManage complex bills of materials, inventory tracking, and purchase ordersDevelop relationships with equipment vendors and field service engineersEvaluate and recommend engineering changes to existing devices and equipment in order to improve reliability, manufacturability, serviceability, and decrease cost.
Preferred Qualifications;B.S. or M.S. in Engineering with preference for Mechanical, Electrical, Chemical, Controls, or Process Engineering or a related Science field with appropriate automation experience.Minimum of 5+ years (Senior); 7+ years (Staff) experience with automation systems and transferring complex workflows into a high-throughput operation. Preference given to experience from the life science industry, but relevant experience from other industries will be considered (e.g. manufacturing in the food & beverage, pharmaceutical, chemical, agricultural, automotive industries)Experience implementing robotic workcells, preferably in a laboratory automation environment.Proven track record leading complex automation projects involving internal and external teams.Demonstrated delivery of automated systems into production environments.Comfortable managing projects and relationships through 3rd party contractors.Proficient in SolidWorks 2020 or later Experience designing and prototyping parts/assemblies using CAD systemsExperience developing control systems using PLCs or other I/O infrastructure (e.g. Allen Bradley, Beckhoff, Siemens, Labview, Arduino, etc.)Experience developing HMI/SCADA systems ( e.g. Ignition, FactoryTalk, Wonderware, etc.) Hands on experience troubleshooting electro-mechanical systemsProven track record working with machine shops for prototyping and manufacture of custom designed parts (e.g. 3D printing, machining, injection molding, etc.)Familiarity with P&ID and electrical schematics Highly energetic and self-motivated. Able to work independently and as part of a team.Analytical, creative thinker, ability to solve problems.Effective organizational and time management skills.
Nice To Have; Experience working with a broad set of laboratory instruments and tools.Experience working in a regulated environment (CLIA / CAP / FDA / ISO).Experience in reagent manufacturing, ideally in a regulated environment (cGMP).Experience with C#, powershell, pythonExperience or knowledge of communications protocols such as OPC, ModbusKnowledge of GD&T as it applies to machined parts and assemblies

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