Supervisor- Bioanalytical Chemistry

4 weeks ago

Cleveland, Ohio, United States Charles River Laboratories, Inc. Full time

For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we'll help you build a career that you can feel passionate about.

Job Summary

We are seeking a Supervisor for our Bioanalytical Chemistry team at our Safety Assessment Site located in Cleveland, OH.

Discipline Summary:

Bioanalytical Chemistry supports the evaluations of test compounds by providing bioanalytical quantitative analysis of drug in body fluids and tissues from non-regulated and regulated studies including preclinical safety evaluations, pharmacokinetic/pharmacodynamic studies, and clinical trials. Staff participate in the development and validation of quantitative LC/MS/MS methodology, sample analysis, and interpretation and reporting of data utilizing validated hardware and software systems. This includes the development of sample extraction techniques, rapid LC separations, and employment of laboratory robotics to enhance delivery time of bioanalytical data. Staff are also knowledgeable in the application of GxP's and applicable SOPs, along with adhering to study protocols to accurately document methods, procedures, and results for inclusion into study reports and regulatory documents.

Essential Functions (The fundamental Competencies/Skills & Responsibilities of the role (products and services provided/results accomplished) include, but are not limited to, those listed:

  • Efficiently perform supervisory responsibilities in accordance with organizational policies and applicable laws to include interviewing, hiring, training and developing employees
  • Develop organizational strength by hiring, identifying and developing personnel who are scientifically and/or technically strong
  • Establish culture and atmosphere to maintain good retention and low turnover using available tools and metrics
  • Assist with providing costing estimates for components of applicable studies
  • Provide short- and long-term solutions that support continuous improvement
  • Develop critical thinking, troubleshooting and time management skills aligned with needs of operational areas
  • Demonstrate effective communication skills through informal discussions with peers, supervisor, and team
  • Ensure laboratory tasks and operations are executed in compliance with SOPs, protocols, regulatory requirements
  • Establish and review Standard Operating Procedures (SOPs), protocols, policies, best practices and study procedures
  • Develop contemporaneous knowledge of regulatory requirements
  • Effectively plan, assign and direct work within one operational area
  • Performs all other related duties as assigned

The pay for this position is $72K. Please note that salaries vary within the range based on factors including, but not limited to, experience, skills, education, certifications, and location

Job Qualifications

(Knowledge, Experience, Skills and Abilities required to accomplish the essential functions) include but are not limited to:

  • Bachelor's degree or equivalent with 5-7 years of relevant experience. No previous management experience required
  • An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above
  • Ability to communicate verbally and in writing at all levels inside and outside the organization
  • Basic familiarity with Microsoft Office Suite
  • Computer skills, commensurate with Essential Functions, including the ability to learn a validated system
  • Ability to work extended hours beyond normal work schedule to include, but not limited to evenings, weekends, extended shifts, and/or extra shifts; sometimes on short notice
  • Ability to work under specific time constraints

About Safety Assessment

Charles River is committed to helping our partners expedite their preclinical drug development with exceptional safety assessment services, state-of-the-art facilities and expert regulatory guidance. From individual specialty toxicology and IND enabling studies to tailored packages and total laboratory support, our deeply experienced team can design and execute programs that anticipate challenges and avoid roadblocks for a smooth, efficient journey to market. Each year approximately 300 investigational new drug (IND) programs are conducted in our Safety Assessment facilities.

About Charles River

Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients' clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.

With over 20,000 employees within 110 facilities in over 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client's unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world.

At Charles River, we are passionate about our role in improving the quality of people's lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of 86% of the drugs approved by the FDA in 2021.

Equal Employment Opportunity

Charles River Laboratories is an Equal Opportunity Employer - all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.

If you are interested in applying to Charles River Laboratories and need special assistance or an accommodation due to a disability to complete any forms or to otherwise participate in the resume submission process, please contact a member of our Human Resources team by sending an e-mail message to [email protected]. This contact is for accommodation requests for individuals with disabilities only and cannot be used to inquire about the status of applications.

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