Sr. Scientist

Job Description

The Neuroscience Department is seeking a highly motivated, flexible, and technically skilled Senior Scientist with expertise in cellular and molecular biology to join the Neurocircuits Team at the West Point Site. The Team conducts all aspects of pharmacological/biochemical research related to the development of pre-clinical candidates for a wide variety of neuroscience programs.

The successful candidate will have a background in immunoassay development, biochemistry, pharmacology, or physiology. They will demonstrate a solid foundation with respect to their background education through the implementation of in vivo/ex vivo biochemical experiments to determine the efficacy of compounds for neuroscience indications. In addition, the candidate should have extensive experience in data collection, statistical analysis and the interpretation of data in the context of a pre-clinical research environment. Experience with biomarker assay development using a variety of biochemical and/or enzymatic assays related to proteinopathies associated with neurodegenerative diseases is desired.

Key responsibilities:

• Independently implement, perform and troubleshoot a range of in vivo and ex vivo experiments including those related to biochemistry, biomarker assays, and physiology for neuroscience-related indications.
• Transparency and ability to maintain accurate records such that data are reproducible by someone skilled in the art.
• Exhibit leadership qualities within and across departmental collaborations to drive research projects/programs with the ultimate goal of positively impacting patient's lives.
• Interface with others across the organization including disease area biologists, and specialists in safety assessment, chemistry, and pharmacokinetics & drug metabolism to drive drug discovery decision making.
• Establish and manage external research collaborations on an as needed basis.

Education:

• Ph.D. degree in in neuroscience or a related discipline with postdoctoral experience or other relevant work post Ph.D, OR Master's degree in abovementioned discipline with at least 3 years of relevant work experience, OR Bachelor's degree and at least 6 years of relevant work experience

Required:

• Ability to design and execute immunoassays (e.g. ELISA, alphaLISA, SIMOA) using brain and fluid samples and assess efficacy/translational biomarker readouts.
• Excellent data analytical and problem-solving skills with experience using standard scientific software for data analysis and graphing.
• Team player with a collaborative personality and ability to work in a matrixed organization.
• Excellent oral and written communication skills, including experimental records and oral presentation skills.
• Proven track record of scientific accomplishment including generating publication quality data and contributing to manuscript or patent preparation.

Preferred:

• Extensive experience with molecular biology and imaging assays such as high-content imaging platform, qPCR, Western blot, etc.
• Expertise in cell culture techniques and development of in vitro functional assays using genetic and pharmacological manipulation.
• Familiarity with animal handling requirements including drafting animal procedure statements, and the safe handling and dosing of laboratory animals.

NOTICE FOR INTERNAL APPLICANTS

In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.

If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.

Employees working in roles that the Company determines require routine collaboration with external stakeholders, such as customer-facing commercial, or research-based roles, will be expected to comply not only with Company policy but also with policies established by such external stakeholders (for example, a requirement to be vaccinated against COVID-19 in order to access a facility or meet with stakeholders). Please understand that, as permitted by applicable law, if you have not been vaccinated against COVID-19 and an essential function of your job is to call on external stakeholders who require vaccination to enter their premises or engage in face-to-face meetings, then your employment may pose an undue burden to business operations, in which case you may not be offered employment, or your employment could be terminated. Please also note that, where permitted by applicable law, the Company reserves the right to require COVID-19 vaccinations for positions, such as in Global Employee Health, where the Company determines in its discretion that the nature of the role presents an increased risk of disease transmission.

Current Employees apply HERE

Current Contingent Workers apply HERE

US and Puerto Rico Residents Only:

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

We are an Equal Opportunity Employer, committed to fostering an inclusive and diverse workplace. All qualified applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status, or other applicable legally protected characteristics. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

EEOC Know Your Rights

EEOC GINA Supplement​

Pay Transparency Nondiscrimination

We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively.

Learn more about your rights, including under California, Colorado and other US State Acts

U.S. Hybrid Work Model

Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, generally Tuesday, Wednesday and either Monday or Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence. This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as "remote".

Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

Employee Status:

Relocation:

VISA Sponsorship:

Travel Requirements:

Flexible Work Arrangements:

Shift:

Valid Driving License:

Hazardous Material(s):

Job Posting End Date:

*A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

Job Posting End Date:08/05/2024

A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

Requisition ID:R306612