Post-Doctoral Associate

3 months ago

Minneapolis, Minnesota, United States University of Minnesota Full time
Apply for JobJob ID349249
LocationTwin Cities
Job FamilyAcademic
Full/Part TimeFull-Time
Regular/TemporaryRegular
Job Code9546
Employee ClassAcad Prof and Admin
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About the Job

The position is in the laboratory of Peter B. Kang in the Neurology Department at the University of Minnesota. We study the genomics of muscular dystrophy and the role of the Notch pathway in muscle disease. The new position will focus on the latter project, focusing on cellular and animal studies of how Notch pathway dysfunction can cause muscle disease and how certain components of the Notch pathway can serve as therapeutic targets. The researcher will be encouraged to become more independent over time and gain greater autonomy with regard to experimental design.

Job Duties/Responsibilities:

Responsibilities
* Maintain mouse colonies relevant to current scientific projects
* Conduct functional motor assays on mice
* Dissect skeletal muscles and other tissues from mice post-mortem
* Conduct experiments on myoblasts and muscle stem cells isolated from mouse skeletal muscle
* Modify cells under study with recombinant DNA techniques
* Complete protein purification and assessment related activities, RNA and DNA isolation related activities, and perform real-time PCR related activities
* Participate in laboratory meetings, presenting in rotation with other laboratory members
* Work with and train new laboratory members on general skills and specific techniques
* Keep up with appropriate literature
* Maintain detailed and well-organized records of daily experiments
* Prepare manuscripts for publication

Activities will fall within the following areas with estimated effort distribution:

Research Activities: 80%

* Assist in the planning of research activities, in conjunction with the Principal Investigator, to ensure adherence to the project/study timeline(s).
* Design laboratory experiments; oversee their execution; and review, approve, or interpret results
* Independently develop methods and techniques to troubleshoot errors and adjust experimental designs as necessary based on experimental data analysis
* Collaborate with researchers and other professionals to conduct appropriate analyses, analyze problems, determine strategies, or recommend solutions.
* Develop new methods to study the mechanisms of biological processes; develop guidelines for procedures and incorporate new diagnostic procedures
* Search scientific literature to select and modify methods and procedures most appropriate for research goals
* Maintain accurate laboratory records that record research methods, procedures, and results.

Laboratory Management/Regulatory Compliance: 5%
* Help to ensure regulatory compliance for lab activities, including submission and maintenance of relevant IACUC protocols.
* Order and reconcile of laboratory supplies in advance of planned experiments.
* Coordinate lab activities/schedule to achieve research objectives.
* Maintaining, update and follow laboratory Standard Operation Procedures (SOPs) as needed to be in compliance with UMN Environmental Health & Safety office.

Scholarly/Administrative Work: 15%
* Conduct independent data analysis and present findings/outcomes to the Principal Investigator
* Draft and/or provide input for technical reports, research papers, scholarly articles, and abstracts
* Preparation of figures for presentations, publications, or grants.
* Assist in preparation of grant proposals and progress reports to funding agencies.


Qualifications

Required Qualifications:
* PhD in molecular biology, genetics, biochemistry, or related field
* 0-2 years post-graduate laboratory experience
* PhD candidates close to graduation date are encouraged to apply
* Excellent attention to detail and intellectual curiosity, ability to conduct multiple concurrent experiments
* Willingness and ability to learn new skills
* Excellent communication skills, verbal and written

Preferred Qualifications:
* Experience with mouse studies, particularly in vivo motor functional assays and post-mortem tissue collections
* Experience with tissue culture, specifically myoblast culture
* Experience with western blot and immunofluorescence techniques


Benefits

Working at the University

At the University of Minnesota, you'll find a flexible work environment and supportive colleagues who are interested in lifelong learning. We prioritize work-life balance, allowing you to invest in the future of your career and in your life outside of work.

The University also offers a comprehensive benefits package that includes:

  • Competitive wages, paid holidays, and generous time off
  • Continuous learning opportunities through professional training and degree-seeking programs supported by the Regents Scholarship
  • Low-cost medical, dental, and pharmacy plans
  • Healthcare and dependent care flexible spending accounts
  • University HSA contributions
  • Disability and employer-paid life insurance
  • Employee wellbeing program
  • Excellent retirement plans with employer contribution
  • Public Service Loan Forgiveness (PSLF) opportunity
  • Financial counseling services
  • Employee Assistance Program with eight sessions of counseling at no cost

Please visit the Office of Human Resources website for more information regarding benefits.


How To Apply

Applications must be submitted online. To be considered for this position, please click the Apply button and follow the instructions. You will be given the opportunity to complete an online application for the position and attach a cover letter and resume.

Additional documents may be attached after application by accessing your "My Job Applications" page and uploading documents in the "My Cover Letters and Attachments" section.

To request an accommodation during the application process, please e-mail or call UOHR


Diversity

The University recognizes and values the importance of diversity and inclusion in enriching the employment experience of its employees and in supporting the academic mission. The University is committed to attracting and retaining employees with varying identities and backgrounds.

The University of Minnesota provides equal access to and opportunity in its programs, facilities, and employment without regard to race, color, creed, religion, national origin, gender, age, marital status, disability, public assistance status, veteran status, sexual orientation, gender identity, or gender expression. To learn more about diversity at the U:


Employment Requirements

Any offer of employment is contingent upon the successful completion of a background check. Our presumption is that prospective employees are eligible to work here. Criminal convictions do not automatically disqualify finalists from employment.


About the U of M

The University of Minnesota, Twin Cities (UMTC)

The University of Minnesota, Twin Cities (UMTC), is among the largest public research universities in the country, offering undergraduate, graduate, and professional students a multitude of opportunities for study and research. Located at the heart of one of the nation's most vibrant, diverse metropolitan communities, students on the campuses in Minneapolis and St. Paul benefit from extensive partnerships with world-renowned health centers, international corporations, government agencies, and arts, nonprofit, and public service organizations.

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