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Bench Scientist

4 months ago

Andover, Massachusetts, United States Pioneer Data Systems Full time

Position Details:

Our client, a world–leading Pharmaceutical Company in Andover, MA is currently looking for an Scientist I (Cell Culture, HPLC) to join their expanding team.



Job Title:
Scientist I (Cell Culture, HPLC)

Duration: 18 months contract, extendable up to 36 months

Location:
Andover, MA

Note:

The client has the right–to–hire you as a permanent employee at any time during or after the end of the contract.


You may participate in the company group medical insurance plan

Job Description:
Bench Scientist

Summary:
The position of an analytical bench scientist specialist is being floated in the Upstream Process Development (UPD) group.

The UPD group is responsible for developing robust processes for cell lines producing protein therapeutics.

These are proteins that are chosen by research units as the candidate molecules for the treatment of various medical conditions spread across oncology, neuroscience, inflammation, and many others.

The processes developed by the UPD group are used in GMP manufacturing facilities to produce the molecules in large quantities for clinical and commercial needs.

Almost all the molecules currently produced employ Chinese hamster ovary (CHO) cells as the host cells.

One of the vital components of process development is controlling the metabolism of the cells in culture.

CHO cells consume large amounts of nutrients including amino acids and other metabolites to produce molecules of interest as well other byproducts.

Quantification of amino acids in the culture medium, protein concentration, as well as several other metabolites and byproducts, are key to building robust processes and ensuring product quality.

The successful candidate will drive the analytical support to the team by performing analytical tests on culture samples.

Responsibilities:
Drive analytical support to the UPD team

Coordinate with the team to receive and manage samples, perform analytical tests, process the data, and provide it back to the scientists.


Perform data analysis using Empower and Microsoft Excel, and compose scientific documents for electronic lab notebooks.

Qualifications:
Bachelor's or Master's Degree in Biotechnology, Biochemical Engineering, Analytical Chemistry, Chemical Engineering, or other related fields

A Minimum of 1+year of related work experience

Basic skills in biotechnology and analytical chemistry

Hands–on experience or at least a basic knowledge of various analytical, cell culture, and molecular biology techniques including but not limited to amino acid analysis using UPLC, titer assay using HPLC, and metabolite analysis using BioHT.


Ability to perform data analysis using Empower and Microsoft Excel

Ability to compose scientific documents for electronic lab notebooks

Location:
This is an onsite role, candidates must be local to Andover, MA