Scientist

3 weeks ago

North Chicago, United States Planet Pharma Full time

Title: Scientist II

What are the top 3-5 skills, experience or education required for this position:

1. Ability and willingness to work with a team in a High Throughput, fast-paced environment

2. Incredible attention to detail is mandatory

3. Experienced with automated liquid handlers such as Hamiltons and Tecans and accurate manual pipetting

4. Experienced in multiple extraction procedures in preparation for Mass Spec analysis of In vivo studies and familiar with how to select them

5. Experienced in training and/or mentoring team members would be a plus


The Quantitative, Translational and ADME Sciences Department in North Chicago, IL is seeking an experienced scientist (II) to conduct routine, medium to high volume in vivo biological sample processing for quantitative Liquid Chromatography/Mass Spectrometry bioanalysis. The candidate should understand the rationale and business needs behind sample preparation for bioanalysis and mentor Junior staff to understand same. The selected candidate will be expected to quickly learn to perform high throughput sample extractions using our processes independently. Automated liquid handling platforms and conventional manual single and multi-channel pipettes will be used. Prior laboratory experience with robotic liquid handlers such as Hamilton platforms or Tecan printing units, knowledge of protein precipitation, liquid/liquid, or solid phase extraction techniques is required.


Key Responsibilities Include:

· Independently process samples from various bio-matrices (biological fluids and tissues) for bioanalysis.

· Timely and accurately operate multiple robotic liquid handling decks, following extraction protocols in LIMS system, and troubleshoot if needed.

· Collaborate with team members including Bioanalytical scientists to ensure seamless and timely execution of in vivo small or large molecule quantitation.

· Maintain excellent documentation of all work including electronic notebooks and protocols

· Work closely with multiple teams across Discovery and QTAS to support ADME Sciences and biomarker sample preparation for bioanalysis.


Qualifications:

B.S or M.S. in Biology, Biochemistry, Chemistry, Biomedical Engineering, Chemical Engineering or related field and 3+ (B.S.) or 1+ (M. S.) years of experience in the pharmaceutical industry.

· Previous experience with operating and troubleshooting high-throughput liquid handling robotic platforms such as Hamilton, Beckman and/or Tecan is required.

· Experience with process development or optimization (may include automating).

· Knowledge of protein precipitation, liquid/liquid extraction, and solid phase extraction.

· Technical aptitude with strong attention to detail.

· Ability to follow protocols accurately and precisely, maintain excellent documentation of all work including electronic lab notebooks.

· Highly motivated individual with a proven ability to work cross functionally. Ability to work well in a collaborative fast-paced team environment, committed to generating high-quality results within tight deadlines and across different projects.

· Passion for problem solving and applying new technologies to further scientific goals.

· Strong communication, interpersonal, and presentation skills

Key Leadership Competencies:

· Builds strong relationships with peers and cross functionally with partners outside of team to enable higher performance.

· Learns fast, grasps the "essence" and can change course quickly where indicated.

· Raises the bar and is never satisfied with the status quo.

· Creates a learning environment, open to suggestions and experimentation for improvement.

· Embraces the ideas of others, nurtures innovation and manages innovation to reality.

Significant Work Activities and Conditions: Continuous sitting or standing for prolonged periods (more than 2 consecutive hours in an 8-hour day)

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