Scientist
6 days ago
12 Month Contract (May extend or convert to permanent)
$36/hour W2
Top 3 Must Have Skill Sets:
- Strong scientific foundation in the understanding and implementation of a wide range of cell-based assays (e.g., TR-FRET, BRET, AlphaLISA, HCS, luminescence and fluorescence-based reporter and/or label-free assays) with experience in the utilization of lab automation across assay development and screening
- Track record of developing, implementing, and performing novel cell-based screening assays in microtiter plates to support early drug discovery research
- Ability to design and implement gene editing (CRISPR knock out/in) workflows enabling the development of targets specific and disease-relevant cell-based assays.
Day to Day Responsibilities:
- The development and optimization of novel cell-based assays ensure successful implementation and routine execution of these assays to support HTS, lead optimization, and mechanism-of-action studies for promising therapeutic targets
- Design and implement laboratory experiments, generate & interpret data supporting the successful development of new assays and test the biological effects of therapeutic agents
- Design, implement, and optimize gene-editing workflows in a manner that enables development and evaluation of cell-based functional assays supporting therapeutic target screening or lead optimization studies
Preferred Qualifications:
- Bachelor's degree with 10+ years postgraduate experience in cell and/or molecular biology or closely related field OR Ph.D./Master’s degree with 5+ years postgraduate experience in cell and/or molecular biology or closely related field
- Experience working as part of a multi-disciplinary team in a biopharmaceutical setting
- Strong scientific foundation in the understanding and implementation of a wide range of cell-based assays (e.g., TR-FRET, BRET, AlphaLISA, HCS, luminescence and fluorescence-based reporter and/or label-free assays) with experience in the utilization of lab automation across assay development and screening
- Track record of developing, implementing, and performing novel cell-based screening assays in microtiter plates to support early drug discovery research
- Ability to design and implement gene editing (CRISPR knock out/in) workflows enabling the development of targets specific and disease-relevant cell-based assays
- Capacity to identify, evaluate, implement, and become proficient in novel laboratory techniques
- Ability to create and establish priorities, manage work plans, and meet timelines
- A flexible approach with strong interpersonal, communication and problem-solving skills
- Demonstrated initiative, teamwork, collaboration, and passion for developing technical expertise across assay development to routine execution
- Familiarity with software and statistical platforms for the analysis of large data sets (e.g., Screener, Spotfire)
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