Scientist

Found in: Appcast Linkedin GBL C2 - 2 weeks ago


Spring House, United States Apex Systems Full time

Seeking a candidate who has an immunology background and experience working with T-cells or other immune cells. In this role, the individual will be responsible for optimizing CAR-directed cell therapy functionality of drug product candidates. Success in this position will require a positive, can-do attitude, the ability to work well within a cross-functional team, and the ability to design and execute in vitro assays to study human T cell biology.

Key Responsibilities:

  • Cell culture of human cell lines, primary human blood cells and iPSC cells.
  • Carry out experiments to determine the function of our cell therapy products by characterizing CAR performance, expression and effects on cells with methods including cytotoxicity assays, flow cytometry, cytokine secretion.
  • Measure cytokines or phospho-proteins in samples using Meso Scale Discovery, capillary electrophoresis (Peggy, Wes, etc..)
  • Analyze results of in vitro assays, make graphs and present findings to the Team, recommend next steps


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