Cell Biologist

Seeking a Cell Biologist to join a growing Biotech company in the Spring House, PA area.

We are seeking trailblazers, motivated to deliver innovative solutions, who are enthusiastic collaborators, driven by a sense of urgency to assist patients.

This is a contract-to-hire opportunity.

Key Responsibilities:

The primary responsibilities of this position include, but are not limited to:

Work independently and as part of an interdisciplinary team to support the development and evaluation of non-viral gene therapies using the company’s novel DNA scaffold technology.

Molecular characterization of biomolecules including DNA-conjugated modalities including peptides, antibodies, proteins, and small molecules.

Test various molecules and modalities for biochemical suitability, potential efficacy and safety using cell-based assays combined with various analytical methods.

Develop cell and molecular assays to assess cell fate, potency and durability of the delivery scaffold and genetic payloads.

Design and test cell-based protocols for transfer to the Development team.

Maintain data acquisition and analysis in electronic laboratory notebook.

Basic Qualifications:

BS degree in Cell Biology, Molecular Biology, Biochemistry, Pharmaceutical Sciences with 2-5 years or a MS degree with 0-3 years of research and development experience.

Experience with mammalian cell culture and knowledge on cell based assays.

Detail-oriented with strong organizational and communication skills.

Experience with DNA and RNA extraction methods and downstream use.

Hands-on experience with standard laboratory equipment and procedures.

Able to digest complex articles and reviews and pull relevant information, ideas, and methodologies for experimental use.

General understanding of cell-based assays and outcomes.

Knowledge of peptide and protein structure and function.

Basic analytical characterization methods.

Preferred Skills/Experience:

Experience with flow cytometry cell-based assays for quantitative assessment of results.

Experience with qPCR, ddPCR and other qualitative and quantitative nucleic acid analysis methodologies.

Experience in performing plate and bead-based pulldown and analytical assays.

Able to troubleshoot experiments and instrument issues.

Only local candidates will be considered.