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Associate Scientist
2 months ago
Title: Associate Scientist/ Scientist I (Protein Characterization)
Work Location: New Haven, CT 06510
Duration: 12 Months Contract
Pay: $35.00 - $38.00 /hr (DOE)
Department: Injectable Drug Product Development group
You will need to have:
BS in Chemistry, Biochemistry, Biophysics, Chemical engineering, or relevant field with 2+ years of experience or MS degree with 1+ years of relevant experience is required.
Solid background in protein chemistry, chemistry, biochemistry, or equivalent is highly preferred.
Position requires scientific and practical knowledge of protein chemistry or drug product process
Previous experience in biotherapeutics development as well as understanding of the biotechnology products life cycle and factors impacting protein molecule stability is a plus
Hands-on experience with instrumentation, used in protein pharmaceutical and analytical development as well as characterization and knowledge of cGMP and quality guidelines is a plus.
Candidate will support stability studies for new drying technologies for drug substance.
Stability studies will include impact to drug product formulations with dried DS.
Additional work may be assigned to support formulation development efforts for existing programs.
This work includes lab work, data generation, analysis and interpretation, as well as data discussion in meetings and report generation.
Ability to take initiative in problem solving and finding solutions to scientific challenges with minimal supervision is preferred
Shows ability to take instructions and execute experiments and other activities with minimal supervision is required
The individual must be able to work in a collaborative setting and has ability to adhere to timelines with minimal supervision is essential
Excellent interpersonal skills are required, as is the strong ability to communicate effectively
This is what you will do:
The position is required to join Injectable Drug Product Development group of client pharmaceuticals’ Analytical and Pharmaceutical Development department.
This position is required to conduct studies to enable Drug Product characterization activities, including combination products at high protein concentration, as well as commercial products.
The job entails experimental work on various aspects of Drug Product characterization, including formulation development, safety risk assessment of excipients as well as process reagents, extractables and leachables, in use compatibility studies for intravenous and subcutaneous administration, process development to support drug product manufacturing support, particulates testing.
The ability to work with minimal supervision as well as part of the team is essential.
The position entails execution of the studies and data processing and compiling to generate and support development reports as well as other required documentation. Understanding of assay development, biotherapeutics development is a plus.
Understanding of the basic principles of protein chemistry and/ordrug product process is required.
Experience with electronic record keeping software, like ELN, EndNote, e-logbooks; maintenance of laboratory instrumentation (organizing PMs, data backup, SW upgrade, etc.) and familiarity with design and maintenance of databases will be a plus.
You will be responsible for:
Execute development studies for pharmaceuticals’ drug candidates and commercial products, support tech transfer activities for internal manufacturing and contract manufacturing sites
Assist in preparation and delivery of internal technical reports and presentations on the executed studies with minimal supervision for the product candidates
Participate in Department meetings and other technical and team building activities
