PMO Oligonucleotide Scientist

Found in: Appcast Linkedin GBL C2 - 2 weeks ago


Morrisville, United States Synoligo Biotechnologies Inc Full time

Since its inception, Synoligo Biotechnologies, Inc. has established itself as a leading go-to service provider for our customer’s mission-critical need for research, diagnostic and therapeutic oligonucleotide. The products we made have already been applied in advancing a scientific breakthrough discovery, improving a diagnostic assay to detect the next pandemic quicker and earlier, and identifying a solution for curing a rare genetic disease.


We are looking for a candidate who shares our vision and would like to make an impact on science and people’s health. The incumbent will perform small to middle scale PMO (phosphorodiamidate morpholino oligomer) oligo synthesis in a high throughput, fast paced, and time sensitive environment utilizing state-of-art equipment.


Key responsibilities and accountabilities

  • Perform the synthesis of PMO oligonucleotide, its small molecule, peptide, or protein conjugates in milligram to gram scale.
  • HPLC purification and downstream processing
  • Perform LC-MS analysis of in-process and final product
  • Perform routine maintenance of equipment used in manufacturing.
  • Maintain batch records, equipment logs and other production records as directed per company procedures.
  • Maintain a clean and orderly Production environment in compliance with safety regulations and internal guideline


Qualifications

  • Bachelor of Science degree and above in Chemistry with organic chemistry focus
  • Prior PMO oligo synthesis experience preferred
  • Hands on experience with HPLC, MS is a plus
  • Self-motivated and able to organize and prioritize multiple tasks

Job Type: Full-time


Benefits:

  • 401(k) matching
  • Dental insurance
  • Flexible schedule
  • Flexible spending account
  • Health insurance
  • Health savings account
  • Life insurance
  • Paid time off
  • Retirement plan
  • Vision insurance

Schedule:

  • 8 hour shift
  • Day shift
  • Monday to Friday