Associate Scientist
2 weeks ago
Bioanalytical Associate- Wilmington, Delaware
This role will focus on supporting in-vitro ADME (Absorption, Distribution, Metabolism, and Excretion) studies and plasma sample analysis in preclinical drug development. The successful candidate will play a pivotal role in the analysis and interpretation of bioanalytical data to support early-stage drug discovery.
Key Responsibilities:
- Support ADME Studies: Conduct routine ADME assays, such as protein binding and metabolic stability, to generate key data supporting drug development decisions.
- Plasma Sample Analysis: Prepare and analyze plasma samples for pharmacokinetic studies, including the measurement of drug concentration, metabolite profiling, and related biomarkers.
- Data Interpretation & Reporting: Analyze data sets, provide scientific interpretation, and communicate results to cross-functional teams in a clear and concise manner.
- Record-Keeping: Maintain concise and accurate records of all study activities in accordance with industry guidelines and company policies.
- Troubleshooting and Continuous Improvement: Troubleshoot assay issues, propose corrective actions, and implement process improvements to enhance the efficiency and reliability of bioanalytical data.
Qualifications:
- Bachelor’s degree in Analytical Chemistry, Biochemistry, or a related field.
- 1+ years of hands-on lab experience in bioanalysis, with a focus on ADME/PK studies and plasma sample analysis.
Technical Expertise:
Hands-on lab experience with ADME screening assays, such as protein binding and microsomal stability. Experience with plasma sample bioanalysis in support of non-clinical pharmacokinetic studies. Experience with LC-MS/MS, HPLC, UPLC, and related analytical techniques for the quantification and characterization of drug candidates in biological samples is a plus. Strong analytical and troubleshooting skills with the ability to interpret complex datasets.
Preferred Qualifications:
- Familiarity with drug discovery and development, especially within preclinical research.
- Experience with quantitative LC-MS/MS bioanalytical techniques and ABSciex mass spectrometers. Knowledge of relevant bioanalytical software (e.g., Analyst, Prism) is a plus.
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