Bioanalysis RA II/SRA

BIOANALYSIS SCIENTIST

12mth contract (goal to convert)

Onsite - Redwood City, CA

The Opportunity:

• Develop LC-MS/MS methods and analyze in vitro and in vivo samples to support ADME, pharmacokinetic, and toxicokinetic studies.
• Perform data analysis, provide reports of experimental results, and upload data to electronic system and electronic notebook.
• Conduct in vitro metabolic stability studies in bio-matrices, including hepatocytes, microsomes, blood, plasma, etc.
• Perform in vitro ADME/DMPK assays, such as CYP inhibition, metabolic profiling, etc.
• Assist in the operation, maintenance and troubleshooting of LC-MS/MS instrument.

Required Skills, Experience and Education:

• BSc or MS in Pharmaceutical Sciences or a related scientific discipline, with 3+ years of industry experiences.
• Hands-on experiences in operating and maintaining an LC-MS/MS system
• Hands-on experiences in LC-MS/MS method development and bioanalytical analysis
• Knowledge of biological sample preparation and extraction techniques for downstream LC-MS/MS analysis
• Hands-on experience in HPLC/UPLC method development

Preferred Skills, Experience and Education:

• Previous hands-on experience in SCIEX QTRAP and/or Thermo Q Exactive mass spectrometers
• Working experience in DMPK lab