Peptide Formulation Director

3 weeks ago


San Francisco Bay Area, United States Meet Full time

A growing company is seeking an individual to provide scientific, technical, and hands-on leadership in support of enabling technologies in peptide delivery and pharmaceutical development. The qualified candidate will:

  • Provide high-level strategic knowledge in identifying and implementing enabling technologies for peptide delivery systems and the development of novel formulations.
  • Be responsible for peptide formulation development from lead optimization to clinical development. The candidate should have experience and/or knowledge in formulation and pre-formulation research, formulation development, and process selection with enabling technologies.
  • Provide technical input and oversight related to formulations, including development work outsourced to CDMOs and contract testing laboratories.
  • Oversee pre-formulation and research formulation activities.

Required Skills:

  • Expertise in drug delivery formulations to enhance peptide oral bioavailability.
  • Formulation and process development of biologics and/or peptides to be delivered through oral and injectable routes, including controlled release and depot formulations.
  • Knowledge of analytical skills related to identified formulations.
  • Excellent communication (both verbal and technical) and interpersonal skills.

Essential Functions:

  • Must have current knowledge of peptide delivery systems (oral and subcutaneous).
  • Plans, designs, implements, and analyzes laboratory experiments to advance scientific knowledge of drug formulations.
  • Must have a strong understanding of the principles and practices of chemistry or pharmaceutical sciences and be able to integrate and apply this knowledge effectively to formulate new peptides.
  • Works closely with senior scientific teams to advance the development of state-of-the-art drug delivery techniques.
  • Represents pharmaceutical sciences in cross-functional project teams for both drug discovery and development.
  • Presents, interprets, and draws conclusions from data for presentations to project teams and senior management.
  • Demonstrates ability in developing methods, techniques, and evaluation criteria for obtaining results and interpreting experimental outcomes.
  • Thinks critically and creatively, works independently, determines appropriate resources for resolving problems, and has strong organizational and planning skills.
  • Ability to coordinate with internal and external quality control, quality assurance, and regulatory personnel to resolve technical issues or procedural deviations.
  • Knowledge of cGMP principles and CDMO oversight for GMP manufacturing is preferred.
  • Authoring contributions to regulatory submissions is a plus.
  • Ability to travel domestically and internationally is expected.

Knowledge, Experience, and Skills:

  • 10+ years of experience in small molecule, biologics, and/or peptide pre-formulation & development with a Ph.D. in a related scientific discipline.
  • Expertise in drug delivery formulations to enhance peptide oral bioavailability.
  • Excellent writing and communication skills.
  • Strong interpersonal skills and experience in interfacing with CMC team members and R&D project teams.

The base pay range for this position at commencement of employment is expected to be between $195,000 and $235,000/year; however, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience.



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