Senior Technician

2 weeks ago

Wayne, United States Charles River Laboratories Full time

Independently perform advanced routine analytical methods, interpret data, and generate reports following in-house SOPs, client test methods, and other documented procedures.


Essential Duties and Responsibilities:

  • Execute laboratory tasks, including reagent preparation, equipment monitoring, routine testing of client samples, and creating cGMP and R&D reports.

Proficiently perform basic routine tests:

  • Appearance
  • Endotoxin
  • HIAC
  • Karl Fischer
  • Osmolality
  • pH
  • SoloVPE

Execute advanced routine testing, including:

  • SDS Page
  • Native Page
  • HPLC Methods
  • N-Terminal Sequencing
  • ELISA Methods
  • Develop and maintain strong pipetting skills (single, multichannel, repeat, reverse).
  • Analyze experimental data and report findings.
  • Conduct technical review of routine data, ensuring complete and compliant data packages.
  • Generate analytical data and reports on time, aligning with internal and client deadlines.
  • Participate in equipment maintenance, qualification, and preventive programs.
  • Maintain a safe laboratory environment, adhering to company policies and regulatory standards.
  • Troubleshoot assays and equipment with minimal supervision.
  • Maintain clear, accurate documentation of all lab work.
  • Create high-quality documentation (e.g., deviation reports) with minimal guidance.
  • Assist in client interactions, technology transfers, and technical discussions.
  • Comply with SOPs, CTMs, and cGMP for all tasks.
  • Mentor and train junior staff and transfer methodologies to analytical staff.
  • Keep training records up to date.
  • Work effectively in a team and independently.


Qualifications:

  • Education: Bachelor’s degree (B.S.) in biochemistry, chemistry, or related discipline.
  • Experience: 3-5 years in an analytical lab, preferably within pharmaceutical, biotech, or CRO environments.


Skills and Knowledge:

  • Understanding of cGMPs and regulatory standards in pharmaceuticals.
  • Proficiency in protein/peptide analytical techniques and lab equipment (e.g., HPLC, Plate Reader, CE, Spectrophotometer).
  • Strong analytical and problem-solving skills.
  • Excellent organizational and communication skills, with attention to detail.
  • Proficiency in MS Word, Excel, Outlook, and lab software (e.g., LIMS).

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