Requirements:
Maintaining Stock Solutions - Nuclear Magnetic Resonance

• Equipment Maintenance
• Manuscript writing
• Ordering Supplies
• At least 1 years of experience with analytical and organic chemistry
• Knowledgeable and be able to perform High
• Performance Liquid

Chromatography

Responsibilities:

Job Description:

Provides laboratory experience needed to assist in performing various chemical experiments and procedures.
Synthesize and optimize radiochemical probes for efficacy in molecular imaging with position emission tomography
(PET).
Utilizes and operates various complex laboratory machines and equipment.
Perform general maintenance and upkeep of equipment and instrumentation.
Documents and analyzes results, produces detailed summaries and reports.
Searches chemical databases for journal articles, patents and related technologies.
Contributes to and writes documents in support of Investigational New Drug (INDs) submissions and scientific
Ublications
Works with staff on exploratory
Records raw data; file data accessibly.
Other
Develop analytical methods for PET radiotracers (e. G., HPLC methods).
Perform PET radiotracers production and analyses in full compliance with pertaining
Regulations (e. G., INDs).
Performs regular syntheses of radiotracers on automated synthesis devices.
Maintains automated apparatus for radiosyntheses.
Performs experimental radiochemistry.
Perform radiochemical analyses on radiotracers, using techniques such as radio

• TLC and

Radio

• HPLC.

Performs organic synthesis of key materials (reference compounds and precursors for labeling) in support of the
Medicinal chemistry program.
Works up and implement new methods.
Ensures radiation safety during radiosyntheses and radioanalytical chemistry operations.
Records raw data; file data accessibly.
Contributes to laboratory activities and findings at laboratory meetings.
Works with staff to prepare laboratory findings for publication and presentation at meetings.
Performs organic synthesis of key materials (e. G., reference compounds and precursors for labeling).
Works with staff on exploratory
Trains staff on new experiments/practices, operation/maintenance of instruments and equipment, safety practices;
Coordinates and monitors overall maintenance of laboratory.
Analyzes organic and inorganic compounds to determine chemical and physical properties, composition, structure,
Relationships between compounds, and reactions.
Performs chemical synthesis and optimization of small molecule probes for use in biological research.
Performs organic synthesis of key materials (e. G., reference compounds and precursors for labeling) in support of the
Medicinal chemistry program.
Adds heat, light, energy or a catalyst to show changes in composition.
Purifies compounds by preparative chromatography
Provides laboratory experience needed to perform various complex chemical experiments and procedures.
Synthesizes and optimizes chemical probes for potency and solubility.
Prepares test solutions, compounds, and reagents and maintains necessary laboratory supplies.
Purifies compounds submitted by chemists.
Schedules, tracks and reports analyses of experiments and procedures.
Leads efforts to automate probe production for increased throughput and improved safety.
Independently provides laboratory experience needed to perform various complex chemical experiments and
Rocedures.
Perform bulk

• Ynthesis, purification and formulation efforts for advanced testing in animal models.

Perform radiochemical analyses on radiotracers, using techniques such as radio

• TLC and

radio

• HPLC.

4
Performs experimental radiochemistry
Performs regular syntheses of radiotracers on automated synthesis devices. 5
Performs PET radiotracers production and analyses in full compliance with pertaining regulations (e. G., INDs) 2
Designs and optimizes chemical experiments and procedures.
Develops novel chemistry methodologies and technologies that advance the field and make recommendations.
Works up and implement new methods
Develops analytical methods for PET radiotracers (e. G., HPLC methods). 1
Trains staff on new experiments and practices, operations and maintenance of instruments and equipment, safety
Ractices, etc.
Trains staff on new experiments, practices, operation and maintenance of instruments and equipment and safety
Ractices.
Complies with training requirements for PET radiotracer production and analysis. 3
Designs, optimizes, and troubleshoots chemical experiments and procedures.
Develops novel chemistry methodologies and technologies that advance the field and make recommendations.
Manages overall maintenance of laboratory.
Maintains staff safety records for compliance.
Coordinates and monitors overall maintenance of laboratory.
Provides scientific expertise needed in order to function as the senior chemist of a large laboratory.
Provides technical and scientific expertise for effective contributions to research through scientific discussions with
Research staff.
Contributes to laboratory activities and findings at laboratory meetings.
Ensures radiation safety during radiosynthesis and radioanalytical chemistry operations
Maintains, operates and calibrates numerous machines for use in various experiments and procedures.
Maintains, operates, and calibrates the HPLC- Mass Spectrometer (HPLC- MS), and three other HPLC systems (2
Electrochemical, and 1 UV detectors).
Maintains automated apparatus for radiosyntheses
Assesses methods and procedures for use in experiments, and makes modifications and improvements to resolve
Roblems and meet specific needs.
Performs comparative studies with older technology; perform evaluations to determine new guidelines.
Maintains accurate, detailed records of experiments, and evaluates and interprets results for validity and scientific
Meaning.
Interprets data; use evolving activity and data to design additional rebounds of analogs.
Works with staff to prepare laboratory findings for publication and presentation at meetings.
Produces research reports and communicate results.
Deliverables
Work products and documents related to developing analytical methods for PET
Radiotracers; performing regular syntheses, experimental radiochemistry, radioanalyses,
Regular radioanalyses, and organic synthesis.

• Daily Work products and documents related to performing organic synthesis of key materials

(reference compounds and precursors for labeling); working with staff on exploratory

• Weekly Work products and documents related to maintaining automated apparatus; working up

And implementing new methods; ensuring radiation safety measures are followed.

• Weekly Work products and documents related to recording and filing raw data; preparing findings

For presentation and publication.

• Daily Work products and documents related to training staff on new experiments/practices,

Operation/maintenance of instruments and equipment, safety practices; coordinating and
Monitoring overall maintenance of laboratory.

• Daily

JOB TYPE

Work Day:
Full Time

Employment type:
Permanent Job

Salary:
Negotiable

Positions available: 1

JOB REQUIREMENTS

Minimal experience:
Unspecified

Gender:
Indistinct

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