Staff Scientist

3 weeks ago


Houston, United States Baylor College of Medicine (BCM) Full time

The Division of Thoracic Surgery of the Michael E. DeBakey Department of Surgery at Baylor College of Medicine is seeking a Staff Scientist in basic and translational research in mesothelioma and esophageal cancer. The Staff Scientist will be the primary scientist to evaluate mitochondria pathways associated with treatment resistance in esophageal cancer. This project will focus on the epigenetic and mitochondrial mechanisms that prevent response to immunotherapy or chemotherapy directly in human tumor samples as well as mice and cell culture. The project will require in vivo assessment in mouse models including already developed patient-derived xenografts (PDX) and patient-derived explants (PDE). Additionally, this position will require some oversight of our mesothelioma project especially with teaching post-doctoral fellows, graduate students, or post-baccalaureate students.

Job Duties
  • Design, plan and execute tumor metabolism experiments including Seahorse XF assays and mitochondrial imaging
  • Design, plan and execute metabolomics experiments
  • Design, plan and perform basic molecular biology and cell culture techniques
  • Train fellows and students on basic molecular biology and cell culture techniques
  • Design, plan and perform experiments using mutation detection, gene expression profiling, chromatin immunoprecipitation, DNA/RNA-protein interactions cell culture, lentiviral transductions, and transcriptomic analysis
  • Design, plan and execute experiments with patient tumor samples
  • Design, plan and execute in vivo experiments using mouse models
  • Perform biostatistical analysis of metabolomic and transcriptomic data
  • Mentor students and postdocs in the lab
  • Write manuscripts and grant applications
  • Perform other job related duties as assigned.
Minimum Qualifications
  • Doctoral Degree. Experience may not be substituted in lieu of degree.
  • Three years of post doctoral research experience.
Preferred Qualifications
  • Advanced skills with basic molecular biology techniques (western blot, PCR, cell culture, transfection)
  • Mouse models experience
  • Experience with lentiviral transductions
  • Thoracic oncology experience is a plus

 

 

Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.


  • Staff Scientist

    3 weeks ago


    Houston, Texas, United States Baylor College of Medicine (BCM) Full time

    The Division of Thoracic Surgery of the Michael E. DeBakey Department of Surgery at Baylor College of Medicine is seeking a Staff Scientist in basic and translational research in mesothelioma and esophageal cancer. The Staff Scientist will be the primary scientist to evaluate mitochondria pathways associated with treatment resistance in esophageal cancer....

  • Staff Scientist

    1 month ago


    Houston, Texas, United States Baylor College of Medicine (BCM) Full time

    The NIH-supported Clinical Genome Resource (ClinGen; ) is in the 3rd phase of funding. The Staff Scientist will be responsible for coordinating panels of experts in developing appropriate specifications (guidance) for hereditary cancer interpretation using the established ClinGen frameworks. The Staff Scientist will also join ClinGen committees that are...

  • Staff Scientist

    1 month ago


    Houston, Texas, United States Baylor College of Medicine Full time

    SummaryThis is a position for a researcher with experience in cell culture, gene targeting, immunology and imaging (electron microscopy, scanning electro microscopy and crypoEM). The Staff Scientist is expected to work independently on establishing cell lines using CRISPR that will allow to study the regulation of telomerase. Will also be expected to work...

  • Staff Scientist

    3 weeks ago


    Houston, United States Baylor College of Medicine Full time

    SummaryThe Division of Thoracic Surgery of the Michael E. DeBakey Department of Surgery at Baylor College of Medicine is seeking a Staff Scientist in basic and translational research in mesothelioma and esophageal cancer. The Staff Scientist will be the primary scientist to evaluate mitochondria pathways associated with treatment resistance in esophageal...

  • Staff Scientist

    1 month ago


    Houston, United States Baylor College of Medicine (BCM) Full time

    The NIH-supported Clinical Genome Resource (ClinGen; clinicalgenome.org) is in the 3rd phase of funding. The Staff Scientist will be responsible for coordinating panels of experts in developing appropriate specifications (guidance) for hereditary cancer interpretation using the established ClinGen frameworks. The Staff Scientist will also join ClinGen...

  • Staff Scientist

    2 weeks ago


    Houston, United States Baylor College of Medicine Full time

    SummaryThe NIH-supported Clinical Genome Resource (ClinGen; clinicalgenome.org) is in the 3rd phase of funding. The Staff Scientist will be responsible for coordinating panels of experts in developing appropriate specifications (guidance) for hereditary cancer interpretation using the established ClinGen frameworks. The Staff Scientist will also join ClinGen...


  • Houston, United States TPC Group Full time

    POSITION SUMMARY: TPC is embarking on a growth phase with a focus on expanding technology and new products which creates an excellent opportunity for someone to join our team and have a sizable impact. We are looking for a corporate Research Scientist (PhD Chemist or ChemE) that: * Will help drive further growth in TPC's businesses through successful...


  • Houston, United States AAAS Full time

    Summary The NIH-supported Clinical Genome Resource (ClinGen; clinicalgenome.org) is in the 3rd phase of funding. The Staff Scientist will be responsible for coordinating panels of experts in developing appropriate specifications (guidance) for hereditary cancer interpretation using the established ClinGen frameworks. The Staff Scientist will also join...


  • Houston, United States TPC Group Full time

    TPC is embarking on a growth phase with a focus on expanding technology and new products which creates an excellent opportunity for someone to join our team and have a sizable impact. We are looking for a corporate Research Scientist (PhD Chemist or ChemE) that: help drive further growth in TPC’s businesses through successful development and...


  • Houston, Texas, United States Client Full time

    Junior Data Scientist (ML/Remote Sensing) Houston - Texas (Hybrid) $70,000 - $100, k + PTO + Healthcare + Dental + Equity + Bonuses Are you a Junior Data Scientist with machine learning and remote sensing experience, looking to work for an exciting start-up company who offer excellent hands on training and structured progression? On offer is a long term...

  • Air Permitting

    1 week ago


    Houston, United States Braun Intertec Full time

    Support a variety of clients with their air compliance and permitting needs. Act as a technical and project lead on a variety of air permitting and compliance projects, while mentoring junior staff and coordinating with senior staff as needed. Mainta Permit, Compliance, Engineer, Scientist, Client Relations, Technology


  • Houston, United States Healgen Scientific Limited Full time

    Job DescriptionJob DescriptionAssociate Scientist – Molecular Biology- Next Generation Sequencing (NGS)Texas Scientific LLC is a biotech company located near the Texas Medical Center in Houston. We are committed to the Genesis of Better Health. The Molecular Laboratory focuses on state-of-the-art technology for comprehensive nucleic acid studies, including...


  • Houston, Texas, United States MD Anderson Cancer Center Full time

    SUMMARYThe Principal Research Scientist is responsible for providing leadership and support for major initiatives related to gynecologic cancer immunotherapy translational research. This role entails developing and implementing research plans associated with clinical trials in collaboration with the Gyn Onc faculty and institutional collaborators. The...


  • Houston, United States Lonza Full time

    United States, Houston (Texas)Today, Lonza is a global leader in life sciences operating across three continents. While we work in science, there’s no magic formula to how we do it. Our greatest scientific solution is talented people working together, devising ideas that help businesses to help people. In exchange, we let our people own their careers....

  • Research Scientist

    5 days ago


    Houston, Texas, United States University of Texas MD Anderson Cancer Center Full time

    SUMMARY The primary function of the Research Scientist is to provide technical expertise and experience to plan, design, coordinate, supervise and carry out research projects in the laboratory of Dr. Jlenia Guarnerio in the Department of Genetics. The Guarnerio laboratory studies the role of the tumor microenvironment in promoting tumor growth and therapy...


  • Houston, United States Houston Methodist Full time

    At Houston Methodist, the Medical Laboratory Scientist Specialist position is responsible for performing both routine and complex analyses at a subject matter expert level, which necessitates knowledge of laboratory techniques, principles, and equipment and their interrelationship. This position exercises good judgment by using critical thinking skills and...


  • Houston, United States CTMC Full time

    Job DescriptionJob DescriptionAbout CTMCCTMC is a pioneering biotech joint venture, formed by National Resilience and MD Anderson Cancer Center, and located in the renowned Texas Medical Center. Our mission is to accelerate cell therapies from bench to bedside. We offer a wide range of cell therapy modalities, including CAR-T, TIL, ETC, and TCR-T. Our expert...


  • Houston, United States CTMC A joint venture between Resilience + MD Anderson Cancer Center Full time

    About CTMC CTMC is a pioneering biotech joint venture, formed by National Resilience and MD Anderson Cancer Center, and located in the renowned Texas Medical Center. Our mission is to accelerate cell therapies from bench to bedside. We offer a wide range of cell therapy modalities, including CAR-T, TIL, ETC, and TCR-T. Our expert team collaborates closely...


  • Houston, United States Houston Methodist Full time

    At Houston Methodist, the Sr Research Data Scientist position is responsible for addressing the best uses of data science and informatics development for providing a competitive advantage or addressing pressing research, clinical or business problems in Houston Methodist (HM) research, operations, and care, as well as to effectively communicate informed...


  • Houston, United States CTMC Full time

    Job DescriptionJob DescriptionAbout CTMC CTMC is a pioneering biotech joint venture, formed by National Resilience and MD Anderson Cancer Center, and located in the renowned Texas Medical Center. Our mission is to accelerate cell therapies from bench to bedside. We offer a wide range of cell therapy modalities, including CAR-T, TIL, ETC, and TCR-T. Our...