Scientist/Sr.Scientist-Immunology

Company Overview:

Prellis Biologics is a dynamic startup revolutionizing immunology. We develop cutting-edge technologies to unlock the immune system's potential and drive innovation in therapeutic development.

Position Overview:

We're seeking an enthusiastic and talented immunologist to play a pivotal role in advancing our groundbreaking in vitro immune system platform. You'll collaborate closely with a multidisciplinary team to develop innovative lymph node organoids, design and execute impactful in vitro assays, and contribute your expertise to in vitro immune process development and antigen/antibody biomolecular engineering.

Responsibilities:

Develop human lymph node organoids and design/execute in vitro assays to build an ex vivo immune system. Employ novel techniques to stimulate and characterize immune cell responses. Leverage your immunology knowledge to contribute intellectually to the development of in vitro immune processes and antibody responses. Collaborate effectively across disciplines to achieve project goals. Be hands-on in the lab (60-80% of the time) and thrive in a fast-paced environment.

Qualifications:

PhD in immunology, cell biology, or a closely related field with 3+ years of relevant industry and/or postdoc experience. Deep knowledge of adaptive immunology, in particular B and T cell biology. Strong understanding of cell-cell interactions, and ligand-receptor signaling pathways. Expertise in experimental design, data analysis, and interpreting complex immunological data sets. Extensive immunology lab experience, including flow cytometry (panel design, data acquisition, analysis, troubleshooting). Proficiency in primary cell isolation and culture, and in vitro assay development/execution.

Skills & Experience (Preferred):

Knowledge of immune tolerance, vaccine development, and systems immunology. Project management expertise. Experience with bioinformatic analysis of proteins and sequences. Familiarity with molecular biology techniques. Experience developing and implementing laboratory systems. Proficiency in FlowJo, GraphPad Prism and DOE software.

Plusses:

Demonstrated scientific progress with first-authored publications in peer-reviewed journals.