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Clinical Scientist, Director, Internal Medicine
2 months ago
The Clinician, Clinical Scientist (CS) will provide leadership in clinical epidemiological study execution ensuring consistency of approach, conduct, result reporting and oversight of core team activities within one or more specialty or primary asset programs. In collaboration with Scientific Affairs (SA) Biostatistics group and Clinical Affairs (CA) Operations, the CS is responsible for execution and project management of their studies. The CS will be responsible for numerous epidemiological studies run either as Pfizer-sponsored or as ResearchCollaborations.The CS is a global position and may support all types of Evidence Generation projects in the US, Europe, Developed and Emerging Markets. As lead of the Study Core Team the CS will lead via a matrix organization Epidemiology, Biostats, Clinical Operations, Medical/Scientific Affairs, Regional, Pfizer laboratory assay group, and external team members. The CS also has a strategic role in partnership with Medical/Scientific Affairs to develop operating plans and study strategies in support of the Clinical Development and Life Cycle plans. Data generated by epidemiological studies is critical evidence needed to support clinical development (planning for Phase 3 efficacy trial, including a series of studies to determine incidence and risk groups to inform Phase 3 methodology and identify trial sites), to obtain optimum Vaccine Technical Committee recommendations, schedules, and public payer option, and to develop studies for post-licensure vaccine effectiveness which are pivotal to fulfil Pfizer's regulatory commitments.
ROLE RESPONSIBILITIES
The RWE Platform Primary and Specialty CS is responsible for leading multiple end to end epidemiological studies across various SOPs (for each study): 1) protocol, study design and training, 2) data review and interpretation, 3) study and/or program scientific and integrity oversight, 4) safety review and communication, 5) regulatory document, study report, and publication preparation and review, and 6) clinical study implementation oversight, with a critical focus on consistency (within regions and globally, including common protocols, CRFs, and databases), quality, data integrity, safety, and alignment with company values.
Represents Clinical Affairs line in program-wide functions on Clinical Project Team, Medical Sub Committee, Clinical Study Teams, Asset Team, Program Teams, and Regulatory Strategy teams as applicable. Contributes to discussions to ensure consistency across all programs.
May provide matrix oversight for other RWE Platform Clinical Scientists within the program. Reviews work, develops staff, and provides ongoing feedback. Responsible for short- and long-term resource planning, priority setting, and filling of resource and skill gaps to address the needs of the program(s).
Using expert knowledge of epidemiologic/observational and TA specific aspects of trials, provides oversight of operational strategic partner involvement at a program or study level. Identifies issues in a timely manner, leads implementation of complex solutions, and/or escalates as appropriate working with Clinical Affairs Lead, Clinical Epidemiologist/Medical/Scientific Affairs Lead and Partner representatives.
Influences management/senior management decisions and is viewed as the Subject Matter Expert on CS decisions impacting a program and potentially the Medical/Scientific Affairs groups.
Collaborates with Medical/Scientific Leads and other team members on epidemiologic and Phase IV study planning activities including contributing to annual Operating Plan and Lifecycle Plan development.
Provides CS leadership role in preparation of regulatory submissions, responses to regulatory queries, and in preparation for program regulatory inspections and audits. In collaboration with the Clinical Affairs Lead and Medical/Scientific Lead, prepares strategy decisions, presents, and discusses data at relevant team, governance, external consultants, KOL and potentially regulatory meetings.
Represents TA Clinical Affairs and may take the lead on company-wide, global process improvement initiatives, and champions process enhancements and solutions for complex issues
BASIC QUALIFICATIONS
Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.
BA/BSc Degree in life sciences or health related field with 10+ years practical experience or MSc/MPH with 8+ years or PhD with 6+ years.
Has strong hands-on experience in epidemiological / observational study design, conduct and analysis.
Has significant experience leading operational and/or strategic study teams.
Has significant experience working independently and collaborating with multiple functional groups within and outside the business line.
Experience within primary or specialty care
Has demonstrated an advanced ability and level of experience with working across multiple studies for incorporation of consistent medical/scientific concepts in multiple protocols and ensuring they meet strategic program objectives.
Has advanced knowledge of the clinical research process and Good Clinical Practices from previous employment experience in the clinical research field.
Has independently authored clinical protocols and other clinical study documents.
Has working knowledge of statistics, data analysis, and data interpretation.
Has experience in managing external vendors for clinical and/or epidemiological studies.
Fluent in English writing, reading, and speaking and has exceptional written and oral communication and cross-functional collaborative skills.
PREFERRED QUALIFICATIONS
MSc/MPH or PhD preferred
Has experience in working in a global setting
Is proficient in MS Office, including Teams, Word, Excel, and PowerPoint
Knowledge or experienced in research for Specialty or Primary Care TA is desirable (i.e. Rare Disease, Migraine, Obesity, Inflammation and Immunology)
Has worked in Industry
O ther Job Details:
Work location: Flexible; 2-3 days onsite/week
Last Day to Apply: September 03 2024
Additional Location Information: Cambridge, MA - South San Francisco, CA - La Jolla, CA -Tampa, FL - Boulder, CO - Lake Forest, IL - Groton, CT - Collegeville, PA - Bothell, WA, Europe Any Pfizer Site
The annual base salary for this position ranges from $161,600.00 to $269,400.00.* In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 20.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.
* The annual base salary for this position in Tampa, FL ranges from $145,400.00 to $242,400.00.
Relocation assistance may be available based on business needs and/or eligibility.
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
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