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Scientist I

4 months ago


North Chicago, United States Orion Group Full time

Scientist I - HPLC, LC-MS/MS
Hourly Pay Rate: $33-36 per hour (medical benefits available at a cost)
6-month initial contract
Position is onsite in North Chicago, IL (Lake County)
Hours: First Shift, Mon-Fri, 8am - 5pm (possibility of earlier than 8am depending on job tasks)

Orion Group is seeking a talented Scientist/Biochemist to join our client's research and development team in North Chicago, IL. This position will be part of the Quantitative, Translational & ADME Sciences Department.

The successful candidate will be responsible for non-regulated quantitative LC-MS/MS bioanalysis of small molecules from in vivo and in vitro samples, including extraction, data analysis and interpretation.

Key Responsibilities:
* Use liquid handling robotics.
* Perform quantitative LC-MS/MS (Liquid Chromatography Mass Spectrometry) analysis of small molecules from various bio-matrices in vivo and in vitro to support PK/PD, ADME, efficacy, and exploratory toxicology studies.
* Basic Operation and troubleshooting of AB Sciex LC-MS/MS systems.
* Maintain excellent documentation of all work including LIMS, test methods, and protocols.
* Work closely with multiple teams across Discovery and DMPK-BA to support bioanalysis.

Qualifications:
* B.S. in analytical chemistry or related field years of relevant academic/pharmaceutical industry experience.
* Knowledge of protein precipitation, liquid/liquid extraction, and solid phase extraction.
* Ability to operate and troubleshoot HPLCs, Leap/CTC PAL autosamplers and triple quad mass spectrometers.
* Experience with quantitative bioanalysis of small molecules.
* Knowledge of chromatographic and analytical methodologies.
* The ideal candidate is detail oriented and committed to generating high-quality results within tight deadlines and across different projects.
* Proven ability to work independently or under minimal supervision in a high-throughput environment to design and conduct experiments, interpret, document, and communicate results, as well as in a team environment to collaborate successfully across other groups within R&D.
* Strong communication, interpersonal, and presentation skills.
* Experience operating and troubleshooting current LC-MS/MS platforms (Agilent HPLCs, Leap/CTC PAL and ADDA autosamplers, Sciex API-5500/6500 triple quad Mass Spectrometers) and software (e.g. Discovery Quant, Analyst, Electronic notebook) is highly preferred.

Key Leadership Competencies:
* Builds strong relationships with peers and cross functionally with partners outside of team to enable higher performance.
* Learns fast, grasps the "essence" and can change course quickly where indicated.
* Raises the bar and is never satisfied with the status quo.
* Creates a learning environment, open to suggestions and experimentation for improvement.
* Embraces the ideas of others, nurtures innovation and manages innovation to reality.

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Our role in supporting diversity and inclusion
As an international workforce business, we are committed to sourcing personnel that reflects the diversity and values of our client base but also that of Orion Group. We welcome the wide range of experiences and viewpoints that potential workers bring to our business and our clients, including those based on nationality, gender, culture, educational and professional backgrounds, race, ethnicity, sexual orientation, gender identity and expression, disability, and age differences, job classification and religion. In our inclusive workplace, regardless of your employment status as staff or contract, everyone is assured the right of equitable, fair and respectful treatment.