LC-MS Scientist
1 month ago
Company Description
Insmed is a global biopharmaceutical company on a mission to transform the lives of patients living with serious and rare diseases. Our most valuable resource is our employees, and everything we do is motivated by a patients-first mentality. We are dedicated to growing our team with talented individuals from around the world who are willing to challenge the status quo, solve problems, and work collaboratively with a sense of urgency and compassion.
Guided by our core values of collaboration, accountability, passion, respect, and integrity, we aim to foster an inclusive, diverse, and flexible work environment, where our employees are recognized for leaning in and rolling up their sleeves. If you share our vision and want to work with the most dedicated people in the biopharma industry, come to Insmed to accelerate your career.
Recognitions
Named Science's Top Employer in 2021, 2022, and 2023
Insmed is dedicated to creating a collaborative environment where our team can thrive. Every day, our employees turn their passion for science and research into innovative solutions for patients. That's why we were named the No. 1 company to work for in the biopharma industry in Science's Top Employers Survey for three years in a row.
A Certified Great Place to Work®
We believe our company is truly special, and our employees agree. In July 2024, we became Great Place to Work-certified in the U.S. for the fourth year in a row. We are also honored to have been listed on the Best Workplaces in Biopharma™, Best Workplaces in New York™, PEOPLE® Companies That Care, Best Workplaces for Women™, Best Workplaces for Millennials™, and Best Medium Workplaces™ lists.
Overview This on-site position is based in Bridgewater, NJ. Insmed R&D team is seeking a Scientist with significant experience with LC-MS. The successful candidate will be responsible for biologics characterization and quantification with high resolution LC-MS to support projects from various teams. This role offers the opportunity to work with a range of modalities, including therapeutic proteins, AAVs, etc. Additionally, the scientist will document methods and studies and present data and results to collaborators from different teams.
Responsibilities Responsibilities:
Independently perform routine peptide mapping, intact/native protein analysis from sample prep, data acquisition, data analysis to data reporting, providing analytical support of various research projects.Develop and optimize new LC-MS method to meet emerging analytical needs. Qualify new method and document them into SOPs. Update existing SOPs to reflect procedural changes.Offer scientific insights and apply critical thinking to the planning and execution of experiments.Perform routine housekeeping to maintain lab compliance, including instrument maintenance, ordering and stocking lab supplies, managing reagents and samples, and adhering to safety protocols. Perform instrument troubleshooting if necessary.Qualifications:PhD in Chemistry, Analytical Chemistry, Biochemistry, or a related field with 0-1 years of post-doctoral experience; or MS with 4+ years of experience; or BS with 6+ years of experience (level commensurate with education and experience).Hands-on experience and deep understanding of LC-MS based protein analysis such as post-translational modifications (oxidation, deamidation, glycosylation, etc.), reduced/intact/native protein analysis, disulfide bond identification, sequence variant analysis.Experience with data analysis and interpretation, along with presenting data to collaborators to support project development. Prior experience with software such as Biopharma Finder, Proteome Discoverer, PEAKS Studio or Protein Metrics software is preferred.Experience with LC-MS maintenance and troubleshooting such as Orbitrap and QTOF systems.Strong interpersonal skills and the ability to work in a fast‑paced, multidisciplinary environment. Strong verbal and written communication skills are essential.Prior experience with host cell protein analysis, AAV characterization or immunopeptidomics is a plus.Prior experience with label-free, TMT or immunoaffinity protein quantification is a plus.
Salary Range
Insmed takes into consideration a combination of candidate's education, training, and experience as well as the position's scope and complexity, the discretion and latitude required in the role, and external market and internal value when determining a salary level for potential new employees.
The base salary range for this job is from $89,000.00 to $119,267.00 per year
Compensation & Benefits
We're committed to investing in every team member's total well-being, now and in the future. We offer a competitive total-rewards package to all employees around the world, including:
Flexible approach to where and how we work, regionally basedCompetitive compensation package including bonus Stock options and RSU awardsEmployee Stock Purchase Plan (ESPP)Flexible Vacation Policy Generous paid holiday schedule and winter breakADDITIONAL U.S. BENEFITS:
401(k) plan with company matchMedical, dental, and vision plansCompany-provided Life and Accidental Death & Dismemberment (AD&D) insuranceCompany-provided short and long-term disability benefitsUnique offerings of pet, legal, and supplemental life insuranceFlexible spending accounts for medical and dependent careAccident and Hospital Indemnity insuranceEmployee Assistance Program (EAP)Mental Health on-line digital resourceWell-being reimbursementPaid leave benefits for new parentsPaid time off to volunteerOn-site, no-cost fitness center at our U.S. headquartersAdditional Information
Insmed Incorporated is an Equal Opportunity/Affirmative Action employer. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law.
Unsolicited resumes from agencies should not be forwarded to Insmed. Insmed will not be responsible for any fees arising from the use of resumes through this source. Insmed will only pay a fee to agencies if a formal agreement between Insmed and the agency has been established. The Human Resources department is responsible for all recruitment activities; please contact us directly to be considered for a formal agreement.
Applications are accepted for 5 calendar days from the date posted or until the position is filled.
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