Postdoc in Tumor Metastasis

Found in: beBee S US - 2 weeks ago


Chicago, United States University of Chicago, Department of Radiation and Cellular Oncology Full time

The University of Chicago’s Ludwig Center for Metastasis Research in the Department of Radiation and Cellular Oncology is seeking Postdoctoral Scholars to join research teams seeking to better understand and reduce the process of tumor metastasis, to elucidate immune responses to radiation, and to improve the anti-tumor action of cancer therapies. Several key collaborations are driving our lab’s current focus: through our ongoing collaboration with Dr. Yang-Xin Fu we continue to investigate core pathways and mechanisms underlying immune responses in the context of radiotherapy and immunotherapy; Dr. Chuan He has been working with us recently to elucidate the effects of modification of m6A methylation on the anti-tumor action of radiotherapy and immunotherapy; and we are partnering with Dr. Wenbin Lin to develop immuno-nanomedicine approaches that can be employed with radiotherapy. Publications from these collaborative investigations over the past decade include Deng et al. Clin Cancer Res 2017, J Clin Invest 2014, and Immunity 2014; Liang et al. Nat Commun 2017; Xu et al. Immunity 2017; Hou et al. Immunity 2018, and Sci Transl Med 2021; Arina et al. Nat Commun 2019, and Cancer Immunol Res 2017; Han et al. Nature 2019; Yang et al. Nat Nanotechnol 2022, and J Exp Med 2021; Hou et al. Clin Cancer Res 2024, Sci Transl Med 2021, and Immunity 2018; Wang et al. J Clin Invest 2023, and Cancer Cell 2023; Jiang et al. Adv Sci (Weinh) 2022, and Biomaterials 2023; Rao et al. Sci Immunol 2021; Zhang et al. EMBO J 2023; Ni et al. Sci Adv 2020; and Chan et al. Biomaterials 2019. This is a diverse and vibrant lab with a long history of breakthrough translational research.

Additional opportunities to consult and/or participate in the composition and execution of translational research grant applications and design and implementation of clinical trials related to immunology and radiotherapy are also available. Qualified applicants must possess a doctorate degree. Ideal candidates would possess a strong background in radiation biology or immunology, with experience in tumor biology and/or tumor immunology, standard immunology techniques/assays, adoptive T- cell therapy, molecular biology, animal models of human cancer, and bioinformatic analysis. Successful Postdoctoral Scholars in our lab independently drive and conduct their research, with guidance and input from the rest of the group, and therefore they must work well in a team environment. The level of the position and compensation are dependent upon qualifications and experience. We are looking for candidates from a diversity of backgrounds; indeed, over the past decade, Postdoctoral Scholars and Fellows in the Weichselbaum Lab have hailed from seven countries. Interested candidates should submit curriculum vitae, bibliography, a statement of research interests, and contact information for at least three references to Dr. R. Weichselbaum, Dept. of Radiation and Cellular Oncology, 5758 S. Maryland Ave, MC9006, Chicago, IL 60637 USA, or via email to: dcorrea@uchicagomedicine.org