Postdoctoral Fellow

2 months ago

Houston, United States University of Texas MD Anderson Cancer Center Full time
A Postdoctoral Position is available in the Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX, United States. The primary purpose of the Postdoctoral Fellow position is to provide technical and specialized skills in Tumor Immunology. This research will involve investigating the cellular/molecular dynamics of innate and adaptive immune cells to develop novel immunotherapy strategies in chronic lymphocytic leukemia. In this regard, xenograft and genetically engineered mouse models as well as patient specimen are employed in both basic and translational studies. A wide set of cellular, basic immunology, advanced flow cytometry, molecular and transcriptome analysis techniques will be utilized to interrogate pertinent questions in several in vitro and in vivo studies. The lab employs genomic tools, novel mouse tumor models and computational approaches to understand the immunological basis of cancer.

The applicant should be self-motivated, able to design and conduct experiments, prepare and present their work at meetings, and write scientific manuscripts; should have skill in setting up and use of laboratory equipment, and ability to assist with development of new and improved methodology. The applicant is expected to train students/technologists when necessary and participate in overall lab management.

LEARNING OBJECTIVES
We are seeking a talented and highly motivated Postdoctoral Fellow to perform hands-on experiments to develop novel mechanism-guided precision therapeutic strategies to address unmet clinical needs in epithelial ovarian cancer (EOC), and to understand the role and mechanisms by which tissue aging influences cancer development and response to cancer therapy by studying cellular senescence. The Postdoctoral Fellow will conduct experiments, perform data analysis and prepare manuscripts in addition to attending lab meetings, journal clubs, and research seminars.

The Postdoctoral Fellow's primary research focus is to help the PI merge mechanistic insights with the translational objectives of experimental therapeutics and the accompanying stratifications of genetic biomarkers to address unmet clinical needs in ovarian cancer. The Postdoctoral Fellow will train, learn and study design, data analysis and manuscript writing.

ELIGIBILITY REQUIREMENTS
Job Specific Competencies:
Ability to work with In vivo mouse models

Skilled in the following analytical techniques:

Tumor immunology & cancer immunotherapy

Mouse handling & injections skills (Intraperitoneal, subcutaneous, retroorbital)

Cell culture of various cancer cell lines & primary cells

Multi-color flow cytometry (FACS) & cell sorting
Single-cell RNA-seq & ATAC-seq

Data analysis & interpretation

Required Experience:
Candidates with immunology background and experiences and with at least one first author-publication in immunology/basic immunology on medium-high impact journals + experience in mouse models, and advanced flow-cytometry acquisition/analysis expertise.

Preferred Experience:
•Evidence of strong scientific productivity demonstrated by high-quality research published in peer reviewed journals.

•Skills for internal and collaborative projects. A strong sense of curiosity and willingness to explore different avenues.

ADDITIONAL APPLICATION INFORMATION
Consideration of application will begin immediately and continue until the position is filled.

POSITION INFORMATION
MD Anderson follows the NIH stipend levels as outlined by the Kirchstein - NRSA . This full-time trainee position will provide a salary between $56,484 to $68,604, dependent upon the years of postgraduate experience.

MD Anderson offers compensated trainees:
- Paid medical benefits (zero premium) starting on first day for trainees who work 30 or more hours per week
- Group Dental, Vision, Life, AD&D and Disability coverage
- Paid Education Vacation and Sick Leave
- Paid institutional holidays, wellness leave, childcare leave and other paid leave programs
- Teachers Retirement System defined-benefit pension plan and two voluntary retirement plans
- Employer paid life, AD&D and an illness-related reduced salary pay program
- Health Savings Account and Dependent Care Reimbursement flexible spending accounts
- Fertility benefits
- State of Texas longevity pay
- Extensive wellness, fitness, employee health programs and employee resource groups

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