Research Associate II, Bioanalytical Development

4 weeks ago

Menlo Park, United States ReCode Therapeutics Full time

Who We Are:

ReCode Therapeutics is a clinical-stage genetic medicines company using precision delivery to power the next wave of mRNA and gene correction therapeutics. ReCode’s proprietary Selective Organ Targeting (SORT) lipid nanoparticle (LNP) platform enables highly precise and targeted delivery of genetic medicines directly to the organs, tissues and cells implicated in disease, enabling improved efficacy and potency. ReCode’s lead programs include RCT1100 for the treatment of primary ciliary dyskinesia caused by pathogenic mutations in the DNAI1 gene, and RCT2100 for the treatment of the 10-13% of cystic fibrosis patients who have Class I mutations in the CFTR gene and do not respond to currently approved CFTR modulators. RCT1100 and RCT2100 are inhaled disease-modifying mRNA-based therapies formulated using the SORT LNP delivery platform. ReCode is expanding its pipeline to develop potential therapies for other rare and common genetic diseases, including musculoskeletal, central nervous system, liver and infectious disease indications.

Summary of Position:

We are seeking a highly motivated and scientifically rigorous individual to join the preclinical translational biology and assay development team. You will be responsible for executing or supporting experiments to meet agreed upon deliverables and timelines. These activities will require a high level of precision and careful attention to details. The successful candidate will collaborate with an inter-disciplinary team of ReCode scientists and will have access to excellent experimental and analytical facilities.

Responsibilities:

Plan, execute, analyze, and troubleshoot assays for detection of proteins target and mRNA from experimental cell cultures and animal tissues. Work under direction of a scientist to perform and optimize detection and functional assays of novel targets using automated western blot (Jess system), Elisa, MSD assays, and qPCR. Collaborate intra- and inter-teams to work on several different projects. Maintain good laboratory practice and documentation.

Qualifications:

Bachelor’s/Master's degree in molecular biology or related field with 1-2+ years of lab experience in the biopharma industry. Hands-on relevant experience in protein and nucleic acids is a must. Strong knowledge of basic principles of protein extraction, RNA extraction, PCR, qPCR, Elisa, and automated Western Blot analysis using Jess system Hand-on experience with automated western-blot, Elisa and MSD is highly desired. Ability to maintain accurate and well-organized laboratory records, including electronic notebooks. Excellent organizational and oral/written communication skills. Strong analytical, troubleshooting, and problem-solving skills. Works independently as well as collaboratively within groups and interdisciplinary team. Desire to work in a fast-paced environment.

Salary Range: $45-$55/hr

Benefits Offered for Full-Time Employees: 

No premium cost for employees - 100% subsidized by ReCode for full-time employees Company 401k contribution 15 days of company paid holidays, including a holiday shutdown (usually the last week of the year) Mental health support for employees & their families FSA available, including a lifestyle spending account subsidized by company Employee discounts at hotspots

ReCode Therapeutics (www.recodetx.com) offers a competitive compensation/benefits package with a friendly, collaborative culture that values employee engagement and ongoing career development.

ReCode Therapeutics is an Equal Opportunity Employer.

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