Current jobs related to Principal Scientist, Process Engineering - Collegeville - PerkinElmer

  • Principal Scientist/Investigator

    4 weeks ago

    Collegeville, Pennsylvania, United States GSK LLP Full time

    Job Title: Principal Scientist/InvestigatorAre you passionate about designing innovative solutions to develop medicines for patients? We are seeking a highly skilled Principal Scientist/Investigator to join our Sterile Process Engineering team.About the RoleThis is an exciting opportunity to work with a talented team of engineers, scientists, and automation...

  • Principal Scientist

    4 weeks ago

    Collegeville, Pennsylvania, United States PerkinElmer Full time

    Job SummaryWe are seeking a highly skilled Principal Scientist - Process Engineering to join our team at PerkinElmer. As a key member of our biopharmaceutical development team, you will be responsible for conducting laboratory experimentation and analytical testing of putative formulations and drug product manufacturing.ResponsibilitiesConduct laboratory...

  • Principal Scientist

    4 weeks ago

    Collegeville, Pennsylvania, United States GSK LLP Full time

    Job Title: Principal ScientistWe are seeking a highly skilled Principal Scientist to join our Biomarker and Bioanalytical Platforms (BBP) department at GSK LLP. As a Principal Scientist, you will be responsible for the development and validation of assays to deliver PK and PD endpoints for clinical studies across the GSK portfolio.Key...

  • Senior Scientist, Process Development

    1 month ago

    Collegeville, Pennsylvania, United States PerkinElmer Full time

    Job Title: Principal Scientist, Process EngineeringPerkinElmer is seeking a highly skilled Principal Scientist, Process Engineering to join our team. As a key member of our scientific community, you will be responsible for conducting laboratory experimentation and analytical testing of putative formulations and drug product manufacturing.Key...

  • Senior Scientist, Process Development

    4 weeks ago

    Collegeville, Pennsylvania, United States PerkinElmer Full time

    Job SummaryWe are seeking a highly skilled Principal Scientist, Process Engineering to join our team at PerkinElmer. As a key member of our process engineering team, you will be responsible for leading the development and implementation of process engineering solutions for our biopharmaceutical products.Key ResponsibilitiesConduct laboratory experimentation...

  • Senior Scientist/Researcher

    3 weeks ago

    Collegeville, Pennsylvania, United States GSK LLP Full time

    Job Title: Principal Scientist/InvestigatorJob Summary:We are seeking a highly skilled Principal Scientist/Investigator to join our Sterile Process Engineering team at GSK LLP. As a key member of our team, you will be responsible for designing innovative solutions to develop medicines for patients using Engineering, Process Analytics Technologies,...

  • Senior Scientist, Process Development

    4 weeks ago

    Collegeville, Pennsylvania, United States PerkinElmer Full time

    Job SummaryWe are seeking a highly skilled Principal Scientist, Process Engineering to join our team at PerkinElmer. The successful candidate will be responsible for conducting laboratory experimentation and analytical testing of putative formulations and drug product manufacturing. This is a full-time position with a competitive salary range of $87,360.00...

  • Principal Scientist/Investigator

    4 weeks ago

    Collegeville, Pennsylvania, United States GSK Full time

    Unlock Your Potential in Biopharmaceutical Drug Product DevelopmentGSK is seeking a highly skilled Principal Scientist/Investigator to join our Biopharmaceutical Drug Product Development organization. As a key member of our team, you will be responsible for leading the development of late phase drug product formulation, manufacturing process, and delivery...

  • Principal Statistician, Research Statistics

    4 weeks ago

    Collegeville, Pennsylvania, United States GSK Full time

    Job Title: Principal Statistician, Research StatisticsGSK is seeking a highly skilled Principal Statistician to join our Research Statistics team. As a key member of our team, you will play a critical role in the design, analysis, and interpretation of statistical results for our research studies.Key Responsibilities:Design and implement statistical methods...

  • Packaging Development Scientist

    3 days ago

    Collegeville, Indiana, United States GlaxoSmithKline Full time

    Job SummaryGSK's Packaging, Device and Design Solutions team is responsible for delivering robust, patient-centric devices and primary packaging solutions to support the effective delivery of novel pharmaceuticals across all modalities and routes of administration.As a Packaging Development Scientist, you will be part of a multi-skilled team of Engineers and...

  • Process Engineer

    2 weeks ago

    Collegeville, Pennsylvania, United States SS Industries Full time

    Process Engineer Job DescriptionSS Industries is seeking a highly motivated and detail-oriented Process Engineer to join our team. As a Process Engineer, you will play a critical role in supporting the development, implementation, and optimization of manufacturing and production processes.Key Responsibilities:Design and develop robust manufacturing processes...

  • Process Engineer

    4 weeks ago

    Collegeville, Pennsylvania, United States SS Industries Full time

    Job Title: Process EngineerSS Industries is seeking a highly motivated and detail-oriented Process Engineer to join our team. As a Process Engineer, you will play a critical role in supporting the development, implementation, and optimization of manufacturing and production processes.Key Responsibilities:Design and develop robust manufacturing processes to...

  • Process Engineer

    2 weeks ago

    Collegeville, Pennsylvania, United States SS Industries Full time

    Job Title: Process EngineerSS Industries is seeking a highly motivated and detail-oriented Process Engineer to join our team. As a Process Engineer, you will play a critical role in supporting the development, implementation, and optimization of manufacturing and production processes.Key Responsibilities:Design and develop robust manufacturing processes to...

  • Facilities/Process Engineer

    4 weeks ago

    Collegeville, Pennsylvania, United States GSK Full time

    About the RoleGSK is seeking a skilled Facilities/Process Engineer to join our team. As a key member of our Engineering Services team, you will be responsible for providing engineering support to our Research and Development (R&D) sites.Key ResponsibilitiesProvide ongoing engineering support to R&D Engineering Services Operations, responsible for Facilities...

  • Principal Statistician, Research Statistics

    4 weeks ago

    Collegeville, Pennsylvania, United States GSK Full time

    Unlock the Power of Data in BiopharmaGSK is a global biopharma company that unites science, technology, and talent to get ahead of disease together. As a Principal Statistician, Research Statistics, you will play a key role in our discovery of new medicines, collaborating with outstanding scientists to advance innovative ideas in drug discovery.Key...

  • Process Engineer

    3 days ago

    Collegeville, Minnesota, United States SS Industries Full time

    At SS Industries, we are seeking a skilled Process Engineer to support the development, implementation, and optimization of manufacturing and production processes. This role involves collaborating with senior engineers, production associates, and other cross-functional team members to ensure processes are efficient, cost-effective, and meet quality and...

  • Process Engineer

    1 week ago

    Collegeville, Pennsylvania, United States SS Industries Full time

    Job SummaryThe Process Engineer at SS Industries is responsible for developing, implementing, and optimizing manufacturing and production processes. This includes applying new technology, reducing costs, and implementing lean and Six Sigma methodologies to drive continuous improvement.Key ResponsibilitiesDesign and develop robust manufacturing processes to...

  • Biological Research Scientist

    2 weeks ago

    Collegeville, Pennsylvania, United States Alphanumeric Systems Full time

    Biologist - Bench ScientistWe are seeking a highly motivated and detail-oriented Biologist to join our team as a Bench Scientist. As a key member of our research team, you will be responsible for supporting the in vivo preclinical experimental and clinical needs of the group and scientific partners.Key Responsibilities:Support studies with the team according...

  • Packaging Development Scientist

    3 days ago

    Collegeville, Indiana, United States GlaxoSmithKline Full time

    About the Role:We are seeking a highly skilled Packaging Development Scientist to join our team at GlaxoSmithKline. As a key member of our Packaging, Device and Design Solutions team, you will be responsible for the development of Container Closure System (CCS) solutions within New Product Introduction (NPIs) progressing through Research & Development.Key...

  • Senior R&D/TS&D Specialist

    4 weeks ago

    Collegeville, Pennsylvania, United States Dow Full time

    About the RoleWe are seeking a highly skilled Senior R&D/TS&D Technician to join our team in Collegeville, PA. As a key member of our research and development team, you will provide technical support to lead scientists and technologists in the preparation and execution of experimental activities and studies.Key ResponsibilitiesProvide technical support for...

Principal Scientist, Process Engineering

2 months ago

Collegeville, United States PerkinElmer Full time

Job Responsibilities:

  • Conduct laboratory experimentation and analytical testing of putative formulations & drug product manufacturing
  • Follow administration/delivery approaches for select protein therapeutic assets, including  contributing to, the conception & evaluation of conventional & novel product matrices and administration modalities
  • Partner closely with the manufacturing groups during process development and technology transfers
  • Actively participate with combination drug product assessment and collaborate with device engineering
  • Physicochemical and bioanalytical characterization of native and modified biopharma compounds
  • Collaborate with the Bioanalytical Sciences group to develop & transfer stability-indicating analytical methods for use in product development
  • Oversee release & stability testing; crafting & execution of non-GMP stability protocols to test quality & stability of product formulations
  • Engage with the Analytical Technology Transfer and Stability group to craft GMP stability protocols
  • Assess resultant data; working closely with internal & external discovery and development support partners as needed
  • Maintain accurate, complete laboratory records and ease use of electronic data & information gathering, capture, archiving and communications techniques.
  • Assist in preparation and review of manufacturing batch records, SOPs, and regulatory documentation as appropriate.
  • Maintain training and compliance in areas of health and safety, security, environmental and operational aspects of daily activities in the working environment.

    The selected candidate must possess knowledge and/or competencies related to:

    • Protein and peptide chemistry
    • Formulation and drug delivery/device development
    • Drug product manufacturing

      Nothing in this job description restricts management’s right to assign or reassign duties and responsibilities of this job at any

      Job Requirements and Qualifications:

      Basic Qualification: (Required Education & Experience)  

      • PhD degree in Pharmaceutics, Biology, Chemistry, Chemical Engineering, or related scientific discipline
      • 1-3 years of protein formulation and drug delivery development experience

        OR

        • Master’s degree in Pharmaceutics, Biology, Chemistry, Chemical Engineering, or related scientific discipline
        • 5-7 years of similar experience in protein formulation and drug delivery development experience

          OR

          • Bachelor’s degree Pharmaceutics, Biology, Chemistry, Chemical Engineering, or related scientific discipline
          • 10 or more years of similar experience in protein formulation and drug delivery development experience

            Preferred Experience: (candidates who meet BQs & these qualifications (PQs) especially qualify to be shortlisted for candidate submission)

          • Experience with both conventional and alternative biopharmaceutical protein formulation, and drug product development, including the application of DOE and other statistically based experimental design/interpretation approaches.
        • Experience with protein product manufacturing processes and development (e.g., solution (vial/PFS), or lyophilization; container/closure assessment & selection), drug delivery (e.g., combination product, device & administration kit) feasibility and compatibility evaluation.
      • Experience and understanding of multiple bioanalytical and biophysical assessment techniques for product characterization and product stability evaluation, including HPLC, SDS-PAGE/CGE, SEC, Spectroscopy (UV/VIS, fluorescence, or CD), DSC, particles evaluation by HIAC and/or orthogonal techniques (eg MFI, FlowCam, Archimedes), capillary electrophoresis & chip-based methods, etc.
    • Experience in authoring, contributing to, and critical review of successful regulatory submissions; with particular emphasis on late clinical phase submissions, BLA/MAA filings, response to regulatory questions, and pre-approval inspection experience.
  • Experience in working with in vivo/ in vitro models to critically assess formulation & delivery modalities
Experience in drug product manufacturing technology transfer to commercial and/or scale-up of clinical drug product manufacturing capabilities would be beneficial.

Working Environment:

Must be able to work in a laboratory, controlled environments requiring personal protective equipment (e.g., lab coat, safety glasses, etc.) in laboratory.Job pace may be fast and job completion demands may be high.Must be able to remain in a stationary position more than 25% of the timeThe person needs to occasionally move between labs, corridors, adjoining rooms, and buildings onsite Frequently operate on instruments, objects, tools or controls, which will require regularly bending, squatting, stretching and reaching in order to perform in a service function.Occasionally move or lift up to 25 pounds (potential for occasional lifting of up to 50 pounds).Specific vision abilities required by this position include without limitation, the ability to observe details at close range distance vision, color vision, peripheral vision, depth perception, and ability to adjust focus in order to perform the essential service functions of this position.Occasionally operates a computer and other office machinery, such as a calculator, copy machine, and computer printer.Employee may be required to handle hazardous waste according to local, state, and federal regulations. Duties may include identifying, handling, generating, accumulating, storing and labeling hazardous waste.Potential risk to lab-based hazards including but not limited to extreme temperature, biological materials, and hazardous chemicals.May be required to complete Medical Clearance, Respiratory Protection Training, and Fit Testing to wear a respirator as protection against hazards present in the laboratory environment.

The annual compensation range for this full-time position is $87,360.00 to $131,040.00. The final base pay offered to the successful candidate will be determined by factors including internal equity, work location, as well as individual qualifications, such as job-related skills, experience, and relevant education or training.