Principal Systems Engineer

4 weeks ago

Santa Clara, United States Roche Full time
Roche fosters diversity, equity and inclusion, representing the communities we serve. When dealing with healthcare on a global scale, diversity is an essential ingredient to success. We believe that inclusion is key to understanding people's varied healthcare needs. Together, we embrace individuality and share a passion for exceptional care. Join Roche, where every voice matters.

The Position

A healthier future. It's what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That's what makes us Roche.

We are seeking a passionate Principal Systems Engineer to join our Systems Development Group to support the Next Generation Sequencing (NGS) products. This role is expected to be a hands-on key contributor in feasibility, integration, development, verification and validation phases of end-to-end NGS solution. Hands-on development experience of at least one of the programming languages such as Python, C++ for hardware automation or statistics analysis applications. Working knowledge of bioinformatics workflows including demultiplexing, alignment, variant calling, etc.

The Opportunity:
  • Perform systems development activities as part of the project team to develop new NGS solutions and ensure the product design meets customer needs as well as applicable regulations or standards. May serve as the Systems representative on cross-functional teams and efforts.
  • Participate in developing, and managing large subsystem-level or system-level product requirements, critical parameter management (CPM), configuration management, and traceability analysis.
  • Develop, execute, and document test cases for verification and validation. Ensure complete and comprehensive coverage of requirements in the test campaign.
  • Perform systems integration and testing activities to verify system performance through simulation, tests, and measurements. Assess results for applicability, validity, and conformance to product requirements.
  • Perform product risk management activities using tools such as Hazard Analysis or Failure Modes and Effects Analysis (FMEA) according to Roche's applicable regulatory and quality standards and provide risk mitigation recommendations to the project team.

Who you are
  • Wet lab experience. BS, MS or equivalent experience in engineering, sciences, or related field or Ph.D with 5+ years related experience with thorough technical knowledge proven leadership skills, and proven record of accomplishments. Prefer MS, PhD. with 8-10 years of experience.
  • Strong data analysis skills using standard analysis software (e.g. with JMP) and able to determine how best to represent it visually to managers and stakeholders.
  • Hands-on development experience of at least one of the programming languages such as Python, C++ for hardware automation or statistics analysis applications.
  • Hands-on experience using linux based operating systems and linux command line interfaces

Preferred:
  • Experience with systems reliability as well as hands-on troubleshooting experience with hardware and software is highly desirable. Experience using automated (SW) testing tools to drive systems integration
  • Comprehensive knowledge and understanding of End to End workflow in NGS space with a focus on instrumentation and automation
  • Working knowledge of bioinformatics workflows including demultiplexing, alignment, variant calling, etc. Experience with cloud deployment is desirable.

Relocation benefits are not offered for this role. The expected salary range for this position based on the primary location of Santa Clara, CA is $128,120 and $161,595. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed here: Benefits

Who we are

At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we've become one of the world's leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.

Roche is an equal opportunity employer and strictly prohibits unlawful discrimination based upon an individual's race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, mental/physical disability, medical condition, marital status, veteran status, or any other characteristic protected by law.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

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