Senior Associate Scientist

1 month ago


Pearl River, United States Pfizer Full time
Why Patients Need You

Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best-in-class medicines to patients around the world.

What You Will Achieve

As a Senior Associate Scientist, you will be at the center of our operations and you'll find that everything we do, every day, is in line with an unwavering commitment to quality. You will be focused on developing robust, scalable, and high productivity cell culture processes for the manufacture of biological therapeutics for early- and late-phase clinical programs.

Your significant experience of applying knowledge of principles, concepts, and practices of the discipline will make you a critical member of the team. Your skill and knowledge will help in making decisions that require choosing among limited options. You are proactive in contributing to all team discussions.

It is your innovative scientific temperament that will help in making Pfizer ready to achieve new milestones and help patients across the globe.

The Senior Associate Scientist will be responsible for working with fellow scientists to purify mRNA and recombinant proteins. Responsibilities will include chromatography, column packing, filtration, testing and analysis of in-process samples. The Senior Associate Scientist will be expected to summarize, evaluate the study results, and document the recovery of purification processes. It is also expected that the incumbent will perform analysis/ characterization of isolated macromolecules with various bioanalytical methodologies. Careful documentation of work and presentation of data is required. The job function requires judgment and innovation to achieve a solution within standard practices and procedures. Responsibilities will include conducting experiments, tests, and analysis as part of a variety of research and development activities.

How You Will Achieve It

Compliance with all Standard Operating Procedures (SOPs).
Responsible for generating in-process data and batch records. Works directly with analysts to actively trouble-shoot activities.
Complete all required training courses in compliance with departmental requirements and follow appropriate safety practices in the workplace.
Develop and optimize processes where needed
Collaborate with colleagues within Vaccine Research and Development organization including Bioprocess Fermentation, Analytical, and Formulation Development groups.
Perform upstream and downstream processing of materials in a timely and compliant manner
Perform assays on vaccine products, process intermediates, and related experimental samples using biochemical/analytical tests.
Prepare solutions/reagents.
Present problems and propose solutions in discussions with group members.
Perform assays on vaccine products, process intermediates, and related experimental samples using biochemical/analytical tests.
Satisfactorily complete all safety training in compliance with departmental requirements and follow appropriate safety practices in the workplace
Perform timely notebook entries and review for completed experiments.
Plan and prioritize related recovery / purification activities.
Perform timely notebook entries and review for completed experiments.
Perform other duties as assigned.

Qualifications

Must-Have
BS degree with 3-5 years relevant experience, or a MS degree with 0-2 years relevant experience
A strong background in mRNA biology or protein biochemistry. Hands-on experience with separation techniques is essential. Hands on experience with DNA isolation, PCR, enzymatic reactions is preferred.
Prior experience with bio-processing/purification.
Experience running chromatography experiments with AKTA systems using UNICORN software.
Proficiency with personal computers including word processing, spreadsheets, PowerPoint and relevant scientific software is desirable. Strong verbal and written communication skills are required.

TECHNICAL SKILLS REQUIREMENTS
Knowledge and ability to independently design, plan, and execute purification / recovery activities. Proficiency and ability to utilize various techniques such as FPLC / HPLC, UV-Vis, SDS-PAGE etc. to isolate and characterize purified targets.
Independently analyze and provide conclusions regarding experimental data generated.

Other Job Details:
Last Date to Apply for Job: August 16th, 2024
Work Location Assignment: On Premise

On Premise colleagues work in a Pfizer site because it's needed to get their job done. They may have flexibility to work remotely from time to time, but they are primarily on-site.

The annual base salary for this position ranges from $64,600.00 to $107,600.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 7.5% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.

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