Principal Scientist, Translational Biology

Found in: Jooble US O C2 - 2 weeks ago


Boston MA, United States Verve Therapeutics Inc Full time

The Position

Verve is looking for a Principal Scientist, Translational Biology to lead translational biology research. This individual would be responsible for designing translational and investigative research studies to bridge the gap between early research and clinical studies, thereby supporting the strategic development of gene editing based drug products. This individual will work cross functionally within the nonclinical development team and with the clinical and regulatory teams to provide mechanistic insights and translational capabilities relevant to the development of Verve's gene editing medicines.

Job Responsibilities

* Design and coordinate studies to understand the potential effects of gene editing products

* Interpret and report data from investigative and translational studies to drive mechanistic understanding

* In partnership with R&D teams, facilitate appropriate incorporation of translational medicine strategies for early and late phases of development

* Implement and coordinate innovative biomarkers for defined endpoints based on the best available science and emerging multi-omic technologies

* Utilizes literature reviews, protocols, networking, and prior laboratory experience to advance the pre-clinical and clinical goals of the organization

* Author research papers, abstracts, technical reports, and sections of regulatory documents

* Effectively present and communicate research findings to internal and external collaborators, including upper management, regulatory agencies, and at research conferences

* Collaborate with internal and external stakeholders

* Other duties within the nonclinical development department, as assigned

Qualifications

* Ph.D. in biology or associated life science discipline with strong background/experience in translational science

* At least 10 years of relevant experience

* Strong hands-on experience with translational lab methodologies (ex. cell-based techniques, ex-vivo drug testing and models, PK/PD assays)

* Ability to collaborate and influence at all levels across an organization

* Exceptional written and verbal communication allowing oneself to communicate scientific data and information to others in a digestible format

* Analytical mindset and good problem-solving ability

* Demonstrated ability to critically evaluate and contribute to multiple scientific programs

* Diligence and attention to detail

* Good organizational skills

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