Principal Scientist, Oligonucleotide Synthesis

1 month ago


Boston MA, United States EPM Scientific - Phaidon International Full time

A global pharmaceutical manufacturing company located in the Boston region is looking to add a skilled Principal Scientist to their chemical development team. This individual will need to have expertise in oligonucleotide chemistry and process optimization in both early and late stage. The preferred candidate will also have past experience with the development of large-scale production of oligonucleotides.

Responsibilities

  • Act as a project leader, developing and implementing appropriate strategies for oligonucleotide development
  • Create detailed plans to guide objectives in order to meet project timelines
  • Responsible for technology transfer to kilo lab and pilot manufacturing
  • Mentor and lead scientists
  • Generate reports and present data/updates to internal teams

Qualifications

  • M.S. in biochemistry, chemistry, or related field with 8+ years of experience or Ph.D. with 6+ years of work experience
  • Vast experience in oligonucleotide chemistry including small-scale and large-scale preparation
  • Ability to lead a team and handle various projects at once
  • Experience working in a cGMP production environment
  • Knowledge of statistical methods such as DoE
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