Director / Associate Director Project Toxicologist, Oncology Safety Science, Clinical Pharmacol[...]

Found in: Jooble US O C2 - 2 weeks ago

Gaithersburg MD, United States Workday Full time

Director/Associate Director – Project Toxicologist in Oncology Safety Science, Clinical Pharmacology and Safety Sciences

At AstraZeneca, it is our bold ambition is to eliminate cancer as a cause of death. This is underpinned by our rich pipeline aimed to deliver innovative treatment options for patients. Oncology Safety colleagues contribute to this ambition by accelerating innovative and expert non-clinical safety science.

We are looking to recruit a Director / Associate Director, Project Toxicologist, Oncology Safety to contribute to the development of novel targeted oncology medicines, including Antibody Drug Conjugates. In collaboration with scientists across our Oncology R&D organization, this role will focus on the interface between the discovery and regulatory toxicology team, develop regulatory toxicology strategies to address drug target- and modality-related safety risks, drive progression and acceleration of drug development programs, and develop our safety science to inform the design and selection of novel drug candidates. You will be able to develop your knowledge and skills by working together with experts and leaders in Oncology R&D, safety science, pharmacology, toxicology, drug discovery and development, imaging, pathology, and translational science.

As core member of the project toxicology team, you will design regulatory and investigative toxicology studies to and devise a strategy to predict, assess and mitigate target- and modality-related safety risks on project teams, with a focus on Antibody-Drug Conjugates.
Apply your toxicology knowledge to predict clinical safety and inform decision-making in drug discovery and development programs.
Develop and implement innovative solutions to combine regulatory toxicology with cutting edge science and technologies to progress novel drug candidates to the clinic and through development to the market, in line with business needs.
Communicate clear positions on integrated risk assessments in various formats including informing decision-making governance bodies and contribute to regulatory submissions.
Maintain expertise in regulatory requirements and preclinical safety approaches applied to Antibody Drug Candidates and awareness of industry trends.
Provide specialist non-clinical safety expertise for evaluation of in-licensing opportunities.
Develop Oncology Safety science through collaborative networks across AstraZeneca R&D, external collaborations, publications etc.

Excellent scientist with a PhD and/or DABT in Toxicology, Pharmacology, Oncology, Immunology or related field, a strong scientific track record, and a willingness to challenge conventional thinking.
Experience working as a Project Toxicologist or similar safety focussed role within the pharmaceutical/biotech/CRO project environment.
A proven understanding of drug discovery and development and track record of delivering toxicology programs to enable progression of candidates into the clinic.
Expertise in Oncology, and preferably a solid understanding of drug safety aspects of ADCs.
Experience delivering non-clinical toxicology studies in support of IND applications.
A collaborative, team-oriented approach, able to solve problems in a goal-focused fashion with capacity to coordinate tasks across multiple projects.
Experience and desire to work with teams across geographies including awareness of inclusion and diversity. Level of the role (Director / Associate Director) will be based on experience, understanding of drug discovery and development, and track record of successful contributions to progression of drug projects and scientific accomplishment.
~ Du e t o t h e d iv e r se na tur e o f th e A s tr a Ze neca O n c o l o g y p o rtf ol i o, w e h a v e op p o rtu n i ties f or P r o je ct T o xic o l o gi s t s t o su p p o r t a ra n g e of m oda li ties ac r o s s v a ri o u s pha ses of deve l op m ent.

At AstraZeneca, we follow the science to explore and innovate. Here we have the potential to grow our pipeline and positively impact the lives of billions of patients around the world. We are committed to making a difference by fusing data and technology with the latest scientific innovations to achieve the next wave of breakthroughs. If your passion is science and you want to be part of a team that makes a bigger impact on patients' lives, then there's no better place to be.
We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.
AstraZeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.
#

  • Executive Director, Early Clinical Development Physician, Oncology

    7 days ago

    Gaithersburg, United States Taleo BE Full time

    Follow the science to pioneer new frontiers! Join the team at the heart of AstraZeneca that is committed and encouraged to follow the science. Driven by our curiosity, passion, and determination we are paving the way to change the practice of medicine in Oncology. As leaders of Clinical Development in Oncology, we push the boundaries of science to change the...

  • Associate Director, Lifecycle and Pipeline, Oncology

    7 days ago

    Gaithersburg, United States CareerBuilder Full time

    Job Title: Associate Director, Lifecycle and Pipeline, Oncology Location: Gaithersburg (US) / Barcelona (Spain) There are two positions available reporting across the group. You will report to one of the executive directors within the group. Introduction to role: Join us at AstraZeneca, where we are drawing on the brightest and most diverse minds to impact...

  • Cmc Ra Associate Director Project Leadership

    3 hours ago

    Gaithersburg, United States AstraZeneca Full time

    **CMC RA Associate Director Project Leadership** Are you ready to turn our pipeline into reality and impact unmet patient needs? We are seeking a CMC RA Associate Director Project Leadership to join our Oncology R&D team. The role holder will have the appropriate level of CMC Regulatory Strategy, Operational, tactical, and decision-making expertise for...

  • Senior Medical Director, Principal Patient Safety Physician

    Found in: Jooble US O C2 - 1 week ago

    Gaithersburg, MD, United States AstraZeneca GmbH Full time

    Senior Medical Director, Principal Patient Safety Physician - Oncology! Location: Gaithersburg (3 days on site) Are you ready to bring your deep clinical understanding and judgement to a senior leadership role within Patient Safety at AstraZeneca? As a Senior Medical Director, Principal Patient Safety Physician, you will play a pivotal role in shaping the...

  • Associate Director Study Leader Cell Therapy

    5 days ago

    Gaithersburg, United States Workday Full time

    Are you ready to take our leading Oncology pipeline to the next level? As an Associate Director (AD) Study Leader Cell Therapy, you will be responsible for delivering a single or several smaller Cell Therapy development programs. This role requires a high degree of flexibility and autonomy, as you may also provide expert input to other non-drug programs and...

  • Associate Director Study Leader Cell Therapy

    7 days ago

    Gaithersburg, United States CareerBuilder Full time

    Are you ready to take our leading Oncology pipeline to the next level? As an Associate Director (AD) Study Leader Cell Therapy, you will be responsible for delivering a single or several smaller Cell Therapy development programs. This role requires a high degree of flexibility and autonomy, as you may also provide expert input to other non-drug programs and...

  • Medical Director

    Found in: Jooble US O C2 - 2 weeks ago

    Baltimore, MD, United States Quest Diagnostics Incorporated Full time

    Medical Director, Molecular Oncology The Medical Director for Molecular Oncology is a senior position for a physician with both laboratory and clinical experience who will serve as an expert on the clinical use of somatic molecular testing in cancer. The ideal candidate should have experience with clinical management of patients with cancer and understand...

  • Medical Director

    Found in: Jooble US O C2 - 2 weeks ago

    Baltimore, MD, United States Quest Diagnostics Incorporated Full time

    Medical Director, Molecular Oncology The Medical Director for Molecular Oncology is a senior position for a physician with both laboratory and clinical experience who will serve as an expert on the clinical use of somatic molecular testing in cancer. The ideal candidate should have experience with clinical management of patients with cancer and understand...

  • Associate Director, Clinical Pharmacology and

    7 days ago

    Gaithersburg, United States AstraZeneca Full time

    **Associate Director Clinical Pharmacology and Pharmacometrics (Clinical Pharmacology)** Introduction to Role: Are you ready to make a meaningful impact on patients' lives? We are looking for an Associate Director Clinical Pharmacology to join our dedicated Research & Development team in the Biopharmaceuticals R&D department. This scientific role works...

  • Associate Manager, Performance Management

    Found in: Jooble US O C2 - 3 days ago

    Gaithersburg, MD, United States Workday Full time

    Associate Director, Global Oncology - Breast At AstraZeneca, we are committed to turning ideas into life-changing medicines. We are looking for an entrepreneurial, big-thinking individual to join our team and help us make the impossible a reality. As part of our Oncology Business Unit, you will be working in an environment that is focused on harnessing the...

  • Senior Medical Director, Principal Patient Safety Physician

    1 week ago

    Gaithersburg, United States AstraZeneca Full time

    Senior Medical Director, Principal Patient Safety Physician - Oncology! Location: Gaithersburg (3 days on site) Are you ready to bring your deep clinical understanding and judgement to a senior leadership role within Patient Safety at AstraZeneca? As a Senior Medical Director, Principal Patient Safety Physician, you will play a pivotal role in shaping the...

  • RN Clinic Manager

    Found in: Jooble US O C2 - 1 week ago

    Annapolis, MD, United States US Oncology, Inc Full time

    RN Manager, Clinical Services Medical Oncology Our team at Maryland Oncology Hematology is looking for "star" talent. Maryland Oncology Hematology is dedicated to providing the most advanced cancer care available anywhere in an atmosphere of caring compassion. Position will work in conjunction with, and by the direction of, the Director of Clinical...

  • Senior Director Clinical Programs

    Found in: Appcast US C2 - 1 week ago

    Gaithersburg, United States Zenith LifeScience Full time

    Preferred work locations are Gaithersburg, Maryland or Wilmington, Delaware (Hybrid)Provides expert clinical operational input into project or study level documents, for example clinical development plan, clinical study protocol, clinical study report, and may lead the delivery of study documentsWith oversight from the Senior Director Clinical Programs, may...

  • Senior Director Clinical Programs

    Found in: Appcast Linkedin GBL C2 - 2 weeks ago

    Gaithersburg, United States Zenith LifeScience Full time

    Preferred work locations are Gaithersburg, Maryland or Wilmington, Delaware (Hybrid)Provides expert clinical operational input into project or study level documents, for example clinical development plan, clinical study protocol, clinical study report, and may lead the delivery of study documentsWith oversight from the Senior Director Clinical Programs, may...

  • Associate Director

    1 day ago

    Gaithersburg, United States AstraZeneca Full time

    **Associate Director (Integrated Bioanalysis)** **Bold Disruptors. Push the boundaries of science. Fearlessly break new ground.** Are you ready to work at the cutting-edge, where scientific innovations and an entrepreneurial spirit are the norm? We’re looking for dynamic thought leaders with curious minds, who are comfortable taking smart risks and...

  • Associate Director, Marketing, Lung Tumor Focus

    5 days ago

    Gaithersburg, United States AstraZeneca Full time

    At AstraZeneca, we turn ideas into life-changing medicines. Working here means being ambitious, thinking big, and working together to make the impossible a reality. We're seeking an Associate Director for our Oncology Business Unit, focusing on Lung Tumor Marketing. This role is pivotal in developing and implementing a tumor level strategic plan for the US...

  • CLINICAL DIRECTOR

    Found in: Careerbuilder One Red US C2 - 4 hours ago

    , MD, United States Luminis Health Full time

    Clinical Director - Nursing - Oncology Unit & 2 North Medical Surgical Unit (onsite role)Anne Arunel Medical Center, Annapolis, MDFull Time - Days (M-F) Position Objective: Within the shared governance model, this individual is responsible for comprehensive function and outcomes of defined clinical areas to include compliance with regulations, human resource...

  • Associate Director, Flow Cytometry Specialist

    2 days ago

    Gaithersburg, United States Taleo BE Full time

    Associate Director- Flow Cytometry Specialist- Integrated BioanalysisGaithersburg, USBold Disruptors. Push the boundaries of science. Fearlessly break new ground.Are you ready to work at the cutting-edge, where scientific innovations and an entrepreneurial spirit are the norm? Were looking for dynamic thought leaders with curious minds, who are comfortable...

  • Associate Director, Flow Cytometry Specialist

    3 days ago

    Gaithersburg, United States Taleo BE Full time

    Associate Director- Flow Cytometry Specialist- Integrated Bioanalysis Gaithersburg, US Bold Disruptors. Push the boundaries of science. Fearlessly break new ground. Are you ready to work at the cutting-edge, where scientific innovations and an entrepreneurial spirit are the norm? We’re looking for dynamic thought leaders with curious minds, who are...

  • Regulatory Affairs Director

    2 days ago

    Gaithersburg, United States The Economic Development Alliance for Brazoria Co Full time

    Regulatory Affairs Director - Oncology Cell and Gene Therapy Regulatory Affairs Director - Oncology Cell and Gene Therapy AstraZeneca Pharmaceuticals LP Location: Gaithersburg, Maryland Type: Full-Time, Non-Remote Posted on: April 2, 2024 Apply at Original Source #J-18808-Ljbffr