Scientific Sr. Director

Found in: Jooble US O C2 - 2 weeks ago

San Diego CA, United States Eli Lilly and Company Full time
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.

This is a technical leadership position (Scientific Sr. Director - Group Leader) in the Peptide Discovery Team within Biotechnology Discovery Research in San Diego. The individual will lead a team of scientists that utilize multiple peptide discovery platforms (e.g. diverse peptide libraries, including phage display and in vitro translated peptide libraries) to identify functionally active peptides for a given biological target of interest. These hit/lead peptides will be further optimized for therapeutic applications including development of oral macrocyclic peptides, peptide drug conjugates, and peptide radionuclide conjugates.

In addition, the individual is expected to be an integral part of the collaborations with external partners in peptide discovery activities. The Group Leader will supervise scientists, propose strategies and future directions to meet broader portfolio goals, optimally manage resources, and effectively communicate progress to management and governance committees. Also, will interact cross-functionally within Biotechnology Discovery Research and across Discovery Chemistry, Genetic Medicines, Therapeutic Area Teams, Drug Disposition, Bioproduct Development and Regulatory Affairs.

KEY OBJECTIVES/DELIVERABLES:
  • Lead research efforts to discover hits and drug candidate compounds using multiple peptide discovery platforms and develop new methods and technologies to strengthen the platforms. Apply knowledge of molecular biology, genetic engineering, and chemistry to peptide discovery and optimization activities for a given biological target of interest.
  • Collaborate closely with experts in different fields, such as organic chemistry, computational science, and structural biology. Incorporate knowledge to improve peptide properties such as binding affinity to target or physicochemical properties.
  • In collaboration with peptide chemists, implement rational SAR strategies to improve pharmaceutical properties of therapeutic peptide leads.
  • Drug Hunting Focus: The candidate is expected to exhibit strong problem-solving abilities and be familiar with understanding and resolving issues that lie at the interface of peptide discovery, peptide engineering, pharmaceutical developability and formulation, and biology.
  • Leadership: In advancing the peptide discovery agenda (internally or through external collaborations), the group leader will be required to lead/co-lead multidisciplinary teams. Accordingly, strong communication and presentation skills in sharing research findings and team plans, and effective teamwork will be required.

Basic Qualifications:
  • A Ph.D. degree in chemistry, biochemistry, or molecular biology with a strong focus on peptides.
  • 5+ years of experience in a biotechnology/pharmaceutical company with a demonstrated leadership in peptide discovery and a track record of advancing peptide-based therapeutics, from concept to clinical development.
  • 3+ years of supervisory experience in directing other scientists, including Ph.D. level scientists, in the design and execution of experiments.

Additional Skills and Preferences:
  • Experience using state of the art peptide discovery platforms as demonstrated by publications or patents.
  • Experience with biochemical and cell assay design and development to support peptide discovery efforts.
  • Extensive experience in triaging and validating peptide actives following selection campaigns using various display technologies.
  • Deep expertise in the use of non-coded amino acids to influence structure and activity.
  • Understanding of compound physical chemistry models, measurements, their relationships to ADME properties.
  • Appreciation of peptide formulation requirements and experience incorporating pharmaceutical developability assessment in peptide optimization.
  • Demonstrated ability to work cross-functionally, and excellent organizational, communication and presentation skills.

Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively "Lilly") are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( Lilly_Recruiting_Compliance@lists.lilly.com ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response.

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and help our company develop talented individuals for future leadership roles. Our current groups include: Africa, Middle East, Central Asia Network, African American Network, Chinese Culture Network, Early Career Professionals, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinos at Lilly, PRIDE (LGBTQ + Allies), Veterans Leadership Network, Women's Network, Working and Living with Disabilities. Learn more about all of our groups.

#WeAreLilly #J-18808-Ljbffr

  • Scientific Sr. Director

    Found in: Jooble US O C2 - 2 weeks ago

    San Diego, CA, United States Eli Lilly and Company Full time

    Scientific Sr. Director – Peptide Discovery Team (San Diego, CA) page is loaded Scientific Sr. Director – Peptide Discovery Team (San Diego, CA) Apply locations US, San Diego CA time type Full time posted on Posted 6 Days Ago job requisition id R-60527 At Lilly, we unite caring with discovery to make life better for people around the world. We are a...

  • Sr. Dir/Director of Regulatory CMC

    Found in: Appcast US C2 - 1 week ago

    San Diego, United States BioPhase Full time

    Remote - Candidates must be located in the United States - Ideally Southern California The Sr. Director/Director of CMC Regulatory Affairs will be responsible for developing, leading and executing CMC regulatory strategies and activities for the organization, including the preparation and filing of BLA submissions. This position is a hands-on role, providing...

  • Sr. Dir/Director of Regulatory CMC

    Found in: Appcast Linkedin GBL C2 - 1 week ago

    San Diego, United States BioPhase Full time

    Remote - Candidates must be located in the United States - Ideally Southern California The Sr. Director/Director of CMC Regulatory Affairs will be responsible for developing, leading and executing CMC regulatory strategies and activities for the organization, including the preparation and filing of BLA submissions. This position is a hands-on role, providing...

  • Scientific Sr. Director – Peptide Discovery Team

    Found in: Talent US C2 - 2 weeks ago

    San Diego, United States Lilly Full time

    We’re looking for people who are determined to make life better for people around the world. This is a technical leadership position (Scientific Sr. Director – Group Leader) in the Peptide Discovery Team within Biotechnology Discovery Research in San Diego. The individual will lead a team of scientists that utilize multiple peptide discovery platforms...

  • Sr. Director Regulatory Affairs

    7 days ago

    South San Francisco, United States Life Science People Full time

    Senior Director of Regulatory Affairs Menlo Park, CA Life Science People are currently working with an exciting client, looking for a Sr. Director Regulatory Affairs professional with a strong background in oncology submissions. My client is looking for someone to come in and lead their regulatory efforts in oncology as they pioneer cortisol modulation...

  • Scientific Sr. Director

    5 days ago

    San Diego, United States Eli Lilly Full time

    At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities...

  • Sr. Director Regulatory Affairs

    Found in: Appcast US C2 - 2 weeks ago

    South San Francisco, United States Life Science People Full time

    Senior Director of Regulatory AffairsMenlo Park, CA Life Science People are currently working with an exciting client, looking for a Sr. Director Regulatory Affairs professional with a strong background in oncology submissions. My client is looking for someone to come in and lead their regulatory efforts in oncology as they pioneer cortisol modulation...

  • Sr. Director Regulatory Affairs

    Found in: Appcast Linkedin GBL C2 - 3 weeks ago

    South San Francisco, United States Life Science People Full time

    Senior Director of Regulatory AffairsMenlo Park, CA Life Science People are currently working with an exciting client, looking for a Sr. Director Regulatory Affairs professional with a strong background in oncology submissions. My client is looking for someone to come in and lead their regulatory efforts in oncology as they pioneer cortisol modulation...

  • Scientific Sr. Director

    2 days ago

    San Diego, United States Eli Lilly Full time

    At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities...

  • Scientific Sr. Director – Peptide Discovery Team

    Found in: beBee S US - 3 weeks ago

    San Diego, United States Eli Lilly and Company Full time

    At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities...

  • Director/Sr. Director CMC Regulatory Affairs

    Found in: Jooble US O C2 - 2 weeks ago

    Los Angeles, CA, United States BioPhase Solutions Full time

    Job Description Job Description BioPhase Solutions specializes in recruiting top talented professionals for Southern California's Scientific community. We are currently looking for a Director/Sr. Director, CMC Regulatory Affairs to work for a leading Greater Los Angeles area biotechnology company. The Director/Sr. Director, CMC Regulatory Affairs...

  • Executive Director/ Sr. Director of Medical Affairs

    Found in: Jooble US O C2 - 2 weeks ago

    Redwood City, CA, United States Adicet Bio Inc. Full time

    Executive Director/ Sr. Director of Medical Affairs Overview As a key member of Adicet’s medical team, the head of Medical Affairs will be responsible for setting up and overseeing effective interactions with key opinion leaders, patient advocacy groups, and medical institutions in areas of hematology-oncology and autoimmune diseases relevant to...

  • Associate Scientific Director

    Found in: Jooble US O C2 - 3 weeks ago

    Redwood City, CA, United States Jasper Therapeutics Full time

    Jasper is a biotechnology company focused on developing new therapies to treat both chronic and life-threatening diseases. Our mission is to make safer and potentially curative therapy possible for more patients in need. We are bringing together a team of high performing biotech professionals, leading academic institutions and a strong syndicate of...

  • Scientific Marketing Content Associate

    7 days ago

    San Diego, United States Alimentiv Full time

    At Alimentiv, we are the leading clinical research organization (CRO) in GI diseases focused on Transforming Human Health. With a mission to foster innovation in GI diseases, we invest into R&D to shape the future of clinical trial design and the treatment of chronic inflammatory diseases. We are committed to lead with science, cultivate care, be...

  • Director/Sr. Director, Clinical Pharmacology and PMx

    Found in: Jooble US O C2 - 3 weeks ago

    San Francisco, CA, United States EPM Scientific - Phaidon International Full time

    We are partnered with a growing precision medicine oncology biotechnology company based in San Francisco on an exciting Director/Senior Director opportunity! You will be providing guidance on all Clinical Pharmacology related programs such as authoring protocols, CSRs, data analysis, etc. A key role in this position is to provide PK/PD modeling and...

  • Director/Sr. Director, Clinical Science

    Found in: Jooble US O C2 - 3 weeks ago

    San Francisco, CA, United States Scorpion Therapeutics Full time

    Title: Contract Director/Sr. Director, Clinical Science (Early Oncology Development) Location: San Francisco/Boston/Remote Pay Rate: $95/hour-$150/hour Job Summary Our Clinical Development team has an exciting new opportunity for someone to join as a Contract Director/Senior Director, Clinical Science (Early Development). This person will provide...

  • Executive Medical Oncology Director

    Found in: Jooble US O C2 - 6 days ago

    San Diego, CA, United States RBW Consulting Full time

    Senior/Executive Medical Director, Clinical Development RBW is partnered with a well-funded US based biotech with a startup environment. This biotech focuses on Endocrine and Metabolic Disorders and is looking to potentially expand into other areas. Following positive data in their Phase 2 NASH trial, this biotech is looking to add multiple headcount to...

  • Director/Sr. Director, Clinical Pharmacology and PMx

    7 days ago

    San Francisco, United States EPM Scientific Full time

    We are partnered with a growing precision medicine oncology biotechnology company based in San Francisco on an exciting Director/Senior Director opportunity! You will be providing guidance on all Clinical Pharmacology related programs such as authoring protocols, CSRs, data analysis, etc. A key role in this position is to provide PK/PD modeling and...

  • Director/Sr. Director, Clinical Pharmacology and PMx

    1 week ago

    San Francisco, United States EPM Scientific Full time

    We are partnered with a growing precision medicine oncology biotechnology company based in San Francisco on an exciting Director/Senior Director opportunity! You will be providing guidance on all Clinical Pharmacology related programs such as authoring protocols, CSRs, data analysis, etc. A key role in this position is to provide PK/PD modeling and...

  • Sr Medical Director, Clinical Science

    Found in: Jooble US O C2 - 2 weeks ago

    San Rafael, CA, United States Biomarin Full time

    Before viewing the Sr Medical Director, Clinical Science (PKU) at Biomarin job, please verify that you are a human and not a robot overlord. #J-18808-Ljbffr