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Post-Doctoral Scientist

4 months ago


Indianapolis, United States Lilly Full time

We’re looking for people who are determined to make life better for people around the world.

About Eli Lilly’s Postdoctoral Scientist Program

When it comes to research and development, our goal is to discover and deliver innovative medicines that make life better for people around the world. It’s challenging, expensive and often filled with failure. But even when we fail, we advance medical science and understanding by learning more about diseases, biology and chemistry – ultimately bringing new solutions one step closer to reality. Over the course of our history, we have shed light on some of the toughest health care problems known to man – diabetes, heart disease, infectious diseases, neuroscience disorders, cancer and more. We could not pursue this without our research and development team. Postdoctoral scientists help us continue this pursuit. During your experience you will get:

Top industry research experience Mentoring by some of Lilly’s top scientists Laboratory and classroom training and education to further your development Collaboration and networking across dozens of postdoctoral scientists and other researchers

Are you looking to make a significant difference by contributing to the understanding of the pharmacokinetics & pharmacodynamics of antibody-drug conjugates?

We are seeking an ambitious post-doctoral scientist with strong research and communication skills to contribute to high visible research projects. Your work will contribute to the development of physiologically-based pharmacokinetic/pharmacodynamic (PBPK/PD) models for antibody-drug conjugates (ADCs). In this role, you will:

Contribute to the project research goals and deliverables Develop deep understanding of physiochemical properties, disposition, and mechanism of action of ADC components (antibody, linker and payload) and intact ADCs Establish mechanistic, comprehensive PBPK/PD models for ADCs and identify the key data needed to parameterize a useful PBPK/PD ADC model Use models to predict the effect of intrinsic/extrinsic factors on antibody and payload exposure Identify areas of key need across discovery and clinical development and champion creative solutions to address those needs Maintain external awareness and learning to benefit the organization Present findings at conferences and publish in high quality peer-reviewed journals Working environment – primary mentors in small and large molecule PK/PD, collaboration with relevant functions across the organization

Basic Qualifications

PhD in Pharmaceutics, Computational Sciences, Engineering, or a related field

Additional Skills/Preferences

If you are described with these skills, you could be a great fit for the role:

Self-directed and highly motivated individual who wants to learn new techniques while continually pursuing research and publication goals Excellent communicator (oral and written) with presentation experience, along with a strong publication record Proficient in data analysis and reporting Understanding of pharmacokinetics and/or pharmacodynamic principles Experience in PBPK, QSP, PK/PD, exposure-response modeling or other modeling & simulation related subject area Experience using relevant software such as Phoenix, NONMEM, R, SimCYP, Gastroplus, Monolix, Python, MATLAB, or similar

Additional Information

This position is not permanent. It is for a fixed duration of 2 years with potential to extend to 3 years. You will have opportunities to apply for full time positions after your duration is complete.



Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and help our company develop talented individuals for future leadership roles. Our current groups include: Africa, Middle East, Central Asia Network, African American Network, Chinese Culture Network, Early Career Professionals, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinos at Lilly, PRIDE (LGBTQ + Allies), Veterans Leadership Network, Women’s Network, Working and Living with Disabilities. Learn more about all of our groups.

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