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Research Associate II
4 months ago
Direct Biologics is a market-leading innovator and cGMP manufacturer of regenerative medical products, including a robust extracellular vesicle based biologic platform technology. The Company is committed to providing the latest clinical and scientific information through rigorous and thorough research. With deep knowledge and industry expertise in cellular and regenerative therapies, the company has brought to market a significant development in therapeutic biologics with the introduction of the highest quality production of extracellular vesicles.
Requirements
The research associate level II position at Direct Biologics will perform studies and supporting functions that will advance Direct Biologics’ world leading efforts to develop life changing extracellular vesicle-based therapeutics for the treatment of acute and chronic lung, GI and Neurological disorders. This position will provide scientific support for assay development and mechanism of action studies with the R & D team located in Poway/San Diego, CA. In this role, the RA will:
· Conduct in vitro assays using state of the art nanoparticle characterization methods, cell and organoid culture, immunochemical and biochemical assays, quantitative PCR analysis, sample preparation for proteomics, and miRNA-omics, preclinical and mechanism of action studies.
· Assist in data analysis and generation of reports, and laboratory notebook records.
· Assist in maintaining lab cleanliness and safety, prepare buffers and solutions, and perform other general lab duties.
· Compliance with all regulatory requirements and company policies will be essential to be successful.
· Occasionally work a little longer or on a weekend day if the experiment requires it
STATUS: Full time,Exempt and onsite.
Salary range: 80-100K/yr plus standard benefits; relocation not available for this position
REPORTING STRUCTURE:
· Position reports to the Principal Scientist but will also work with the Lab Operations Manager to assist in science-based support functions on occasion.
QUALIFICATIONS
• Experience with human cell culture and characterization, protein characterization assays (ELISAs, immunostaining-based assays, fluorescent microscopy, western blotting), quantitative PCR, flow cytometry, RNA and protein isolation methods.
• Strong written and oral skills and excellent interpersonal skills.
• Proficiency in data analysis and presentation applications including Microsoft Office apps and statistical software desired
• Must be highly flexible to respond to urgent needs and directional changes in a start-up environment but also have the attention to detail required to execute studies that will be reviewed by the FDA and other regulatory authorities.
• Familiarity of GLP compliant methods and documentation practices.
EDUCATION & EXPECTED EXPERIENCE
· Education: BA or MS in biotechnology, biomedical engineering, cell and molecular biology, biochemistry, or other similar biology related majors.
· Minimum of 2 years biotech based-work experience in cell culture, biochemical, or molecular biology preferred.
Benefits
- Health Care Plan (Medical, Dental & Vision)
- Company 401k match up to 4%
- Paid Time Off
- Holidays
- Stock Option
