Postdoctoral Training Fellow

2 weeks ago

New York, United States The Institute of Cancer Research Full time
Under the leadership of Dr Rachael Natrajan, we are seeking to appoint aPostdoctoral Training Fellow to join our Functional Genomics team. Triple negative breast cancer (TNBC) is an aggressive form of breast cancer characterised by high levels of molecular heterogeneity that underpin its high recurrence rate after neoadjuvant immunotherapy and chemotherapy. There is an unmet clinical need to identify the molecular events that underpin this process and how they evolve over time. Moreover, identifying biomarkers that will aid in predicting which patients will relapse are much needed. We are seeking a highly motivated Post Doctoral Training Fellow for a collaborative project supervised by Dr. Rachael Natrajan and co-mentored by Dr. Esther Arwert, to lead on the biological and mechanistic insights into the evolutionary dynamics of the epigenetic sub-clonal evolution of response to neoadjuvant immunotherapy and chemotherapy in TNBC in vivo mouse models using using high throughput cellular tracking coupled with single cell sequencing and functional genomic screening approaches. These will be linked to single cell epigenetic profiling from TNBC patient samples.

The candidate will perform experimental work to identify epigenetic regulators of neoadjuvant immunotherapy and chemotherapy resistance in TNBC and assess the implications of novel biology using innovative in vivo models and developing genetic screening approaches in vitro and in vivo.

The role will work collaboratively together with a dedicated computational biologist working on the analysis of the single cell and spatial data generated from the wider project goals. See Job reference: Analytical Scientist in single cell & spatial genomics (ID: 1068)

Key Requirements

You should possess a PhD in biology, biochemistry, genetics or other associated subjects and have an excellent track record in biomedical research and experience in cell and molecular biology. Experience with in vitro and in vivo cancer models is essential.

The ICR has a workforce agreement stating that Postdoctoral Training Fellows can only be employed for up to 7 years as PDTF at the ICR, providing total postdoctoral experience (including previous employment at this level elsewhere) does not exceed 10 years

For general information on Post Doc's at The ICR can be found here.

Department/Directorate Information :

The Functional Genomics laboratory headed by Dr. Rachael Natrajan is a multidisciplinary dynamic research group with the mission to develop new treatment strategies for breast cancers resistant to standard of care therapies. We have made novel advances into the understanding of genomic alterations both at bulk and single cell level and their impact on breast cancer in different contexts and how to target these effectively. 

The Functional Tumour Immunology laboratory, led by Dr. Esther Arwert, focusses on uncovering tumour microenvironmental mechanisms that drive immune escape and therapy resistance, using cutting-edge technology and sophisticated mouse models, to investigate how the tumour microenvironment modulates antigen-specific T cell responses.

As part of the ICR's Centre for Cancer Evolution and Translational Immunotherapy Initiatives, we collaborate across disciplines to understand the evolutionary mechanisms of therapy resistance and accelerate the development of more effective, targeted therapies for breast cancer.

  • Postdoctoral Fellow in Mood Disorders Center

    4 weeks ago

    New York, New York, United States Child Mind Institute Full time

    Postdoctoral Fellowship in Mood Disorders CenterThe Child Mind Institute is seeking a highly skilled and motivated postdoctoral fellow to join our Mood Disorders Center. As a postdoctoral fellow, you will have the opportunity to work with a multidisciplinary team of clinicians and researchers to provide comprehensive diagnostic evaluations and treatment to...

  • Postdoctoral Research Fellow

    4 weeks ago

    New York, New York, United States Hospital for Special Surgery Full time

    Postdoctoral Fellow in Arthroplasty ResearchHospital for Special Surgery is seeking a highly motivated Postdoctoral Fellow to join our Arthroplasty Research Lab. The successful candidate will have the opportunity to work on a cutting-edge project to understand how stem cells mediate bone regeneration and orchestrate a composite tissue regeneration...

  • Postdoctoral Research Fellow in Opioid Epidemiology

    4 weeks ago

    New York, New York, United States The University Of Tennessee Health Science Center Full time

    Postdoctoral Fellowship OpportunityThe University of Tennessee Health Science Center is seeking a highly motivated postdoctoral research fellow to join our team at the Center for Opioid Epidemiology and Policy (COEP). As a postdoctoral research fellow, you will have the opportunity to work on cutting-edge research projects focused on the social and policy...

  • Postdoctoral Research Fellow: Co-design of Technology with Children

    4 weeks ago

    New York, New York, United States Sesame Workshop Full time

    Job DescriptionSesame Workshop is seeking a highly skilled Postdoctoral Fellow to join our team at the Joan Ganz Cooney Center. As a Postdoctoral Fellow, you will work under the direction of Dr. Medha Tare to advance positive futures for kids in the digital world.The Cooney Center is an independent research and innovation lab that conducts research on...

  • Postdoctoral Research Fellow in Molecular Epidemiology

    4 weeks ago

    New York, New York, United States Memorial Sloan Kettering Full time

    Research Opportunity:We are seeking a highly motivated postdoctoral fellow to join our NCI-funded research group focused on understanding the genetic architecture of breast cancer and identifying novel molecular biomarkers for gastrointestinal cancers.The postdoctoral fellow will be mentored by Dr. Xiang Shu for a period of two years, with the possibility of...

  • Postdoctoral Research Fellow in Opioid Epidemiology

    4 weeks ago

    New York, New York, United States The University Of Tennessee Health Science Center Full time

    Postdoctoral Fellowship OpportunityNYU Grossman School of Medicine is seeking a highly motivated postdoctoral research fellow to join the Center for Opioid Epidemiology & Policy (COEP) within the Division of Epidemiology, Department of Population Health.Research Focus: The fellow will focus on mentored, applied research on the nature and prevention of...

  • Postdoctoral Research Fellow, Anxiety Disorders Center

    4 weeks ago

    New York, New York, United States Child Mind Institute Full time

    Job SummaryThe Child Mind Institute is seeking a highly skilled and motivated postdoctoral fellow to join our Anxiety Disorders Center. As a postdoctoral fellow, you will have the opportunity to work with a talented team of clinicians and researchers to develop and implement innovative treatment programs for children, adolescents, and young adults with...

  • Postdoctoral Research Fellow

    1 month ago

    New York, New York, United States Child Mind Institute Full time

    Job DescriptionChild Mind Institute is seeking a highly skilled Postdoctoral Fellow to join our team of researchers in the study of brain structure and function using multimodal neuroimaging techniques. The successful candidate will have a strong background in neuroscience, biomedical engineering, or a related field, and significant experience with...

  • Postdoctoral Research Fellow, CDB

    4 weeks ago

    New York, New York, United States Child Mind Institute Full time

    Job SummaryWe are seeking a highly skilled Postdoctoral Fellow to join our team at the Child Mind Institute. The successful candidate will have a strong background in neuroscience, biomedical engineering, or a related field, and experience with multimodal neuroimaging techniques.Key ResponsibilitiesDevelop and apply advanced analytic approaches for...

  • Postdoctoral Research Fellow: Literacy Development and Emerging Technologies

    4 weeks ago

    New York, New York, United States Sesame Workshop Full time

    Job Title: Postdoctoral Research Fellow: Literacy Development and Emerging TechnologiesJob Summary:The Cooney Center at Sesame Workshop is seeking a highly motivated Postdoctoral Research Fellow to join our team. The successful candidate will work closely with our Senior Director of Research to advance our mission of supporting children's learning and...

  • Clinical Psychologist Fellow

    4 weeks ago

    New York, New York, United States Manhattan Psychology Group Full time

    Job OpportunityWe are seeking a highly skilled Clinical Postdoctoral Fellow to join our team at Manhattan Psychology Group. As a Clinical Postdoctoral Fellow, you will have the opportunity to work with a diverse range of patients and develop your skills in evidence-based treatments.Job SummaryThe Clinical Postdoctoral Fellow will work under the supervision...

  • Postdoctoral Research Fellow

    4 weeks ago

    New York, New York, United States Mount Sinai Health System Full time

    About the Role:We are seeking a highly motivated Postdoctoral Research Fellow to join our team in the detection and treatment of lung cancer. As a key member of our research team, you will be responsible for all aspects of lung screening research related to the radiologic interpretation of studies.Key Responsibilities:Conduct research studies on lung cancer...

  • Postdoctoral Fellow, Department of Cell and Molecular Biology, Huang Lab

    6 months ago

    New Orleans, United States InsideHigherEd Full time

    Postdoctoral Fellow, Department of Cell and Molecular Biology, Huang LabLocation:New Orleans, LAOpen Date:Nov 2, 2023Description:The postdoctoral fellows will conduct studies of cellular neurophysiology in the auditory system. The responsibilities for this position will include: experimental design, data collection and analysis, preparing for publications in...

  • Postdoctoral Researcher in Biostatistics

    4 weeks ago

    New York, New York, United States Memorial Sloan Kettering Full time

    Job Summary:We are seeking a highly motivated postdoctoral fellow to join our interdisciplinary microbiome research program at Memorial Sloan Kettering Cancer Center. The successful candidate will work on developing innovative statistical methods and software packages for our unique clinical microbiome database of over 10,000 longitudinal stool samples with...

  • Postdoctoral Researcher

    4 weeks ago

    New York, New York, United States Hospital for Special Surgery Full time

    Overview:We are seeking a highly motivated Postdoctoral Fellow to join our team at the Hospital for Special Surgery. As a leading institution in orthopedic research, we are committed to advancing our understanding of skeletal diseases and developing innovative treatments.The successful candidate will have a recent Ph.D. and/or M.D. in molecular and cellular...

  • Postdoctoral Researcher in Biostatistics

    4 weeks ago

    New York, New York, United States Memorial Sloan Kettering Full time

    Job Summary:We are seeking a highly motivated postdoctoral fellow to join our interdisciplinary microbiome research program at Memorial Sloan Kettering Cancer Center. The successful candidate will work on developing innovative statistical methods and software packages for our unique clinical microbiome database of over 10,000 longitudinal stool samples with...

  • Postdoctoral Research Associate

    1 month ago

    New York, New York, United States New York Botanical Garden Full time

    Job Title:Postdoctoral Research AssociateJob Summary:We are seeking a highly motivated Postdoctoral Research Associate to join our team at the New York Botanical Garden. The successful candidate will work on a collaborative project investigating the evolution and development of sporangia in ferns, leveraging the model fern Ceratopteris. The project aims to...

  • Postdoctoral Research Scientist

    3 months ago

    New York, United States Columbia University Full time

    The Division of Surgical Science of Surgery at Columbia University Vagelos College of Physicians and Surgeons is accepting applications for a Postdoctoral Research Scientist. Under the supervision of the Principal Investigator, the individual will train in developing and participating in a research project that focuses on cellular and molecular mechanism...

  • Postdoctoral Research Associate

    5 days ago

    New York, United States New York Genome Center Full time

    The Singh lab (tjsinghlab.com) is looking for a motivated and creative postdoctoral research associate to lead method development and analysis in statistical human genetics, with a focus on brain disorders. The candidate will develop and apply methods to analyze genetic and phenotypic data from clinical collections and population biobanks that include tens...

  • Postdoctoral Research Scientist Position

    3 weeks ago

    New York, New York, United States Columbia University Full time

    The Division of Surgical Science of Surgery at Columbia University Vagelos College of Physicians and Surgeons is seeking a highly skilled Postdoctoral Research Scientist to join our team. Under the supervision of the Principal Investigator, the individual will train in developing and participating in a research project that focuses on cellular and molecular...