Head of Sales

Location: This position may be performed remotely, but requires the flexibility and willingness to travel as needed.

The Opportunity

Praxis is looking for a bold, mission-driven leader to spearhead sales strategy development and execution across our portfolio - including launch preparation for ulixacaltamide in essential tremor following the positive ESSENTIAL3 readout. This is a hands-on leadership role that will shape and scale our sales function from the ground up. The right candidate has built and led high-performing sales teams across multiple products and therapeutic areas, thrives in fast-paced, cross-functional settings, and knows how to deliver impact from day one. Deep expertise in pharmaceutical sales, sharp analytical instincts, and an ability to lead through ambiguity are must-haves.

Primary Responsibilities

• Develop and implement a comprehensive sales strategy aligned with Praxis' commercial objectives.
• Build, recruit, and lead high-performing sales teams to support product launch and ongoing commercialization efforts.
• Establish sales targets, KPIs, and performance metrics to ensure accountability and drive results.
• Collaborate with marketing and analytics, medical affairs, market access, and other functions to optimize launch readiness and execution.
• Analyze market trends, customer insights, and competitive landscape to identify growth opportunities.

Qualifications and Key Success Factors

• 10+ years of progressive sales leadership in the biotech/pharmaceutical field sales
• Proven track record of successfully building and scaling sales teams
• Experience with CNS therapeutic areas across broad and rare indications and launch experience
• A demonstrated ability to integrate multiple data sources to drive a dynamic sales and customer engagement strategy
• Ability to manage ambiguity in assessing small markets with limited data availability
• Excellent leadership, strategic thinking, and communication skills
• Understanding of HIPAA and importance of data privacy
• Domestic and international travel as required
• The physical and mental requirements of our roles include but are not limited to regular use of a computer, devices or other office equipment, clear communication, and occasional movement. You'll need comfort with screen work, basic hand coordination, and focus. Reasonable accommodations may be made to enable individuals with disabilities to perform these functions.

Compensation & Benefits

At Praxis, we believe that taking care of our people (and their people) is important, so we provide a world class benefits package to help you thrive. This includes 99% of the premium paid for medical, dental and vision plans. We also provide company-paid life insurance, AD&D, disability benefits, and voluntary plans to personalize your coverage. Thinking about the future? We match dollar-for-dollar up to 6% on eligible 401(k) contributions and sweeten the deal with long-term stock incentives and ESPP. We provide a discretionary quarterly bonus, an extremely flexible wellness benefit, generous PTO, paid holidays and company-wide shutdowns. Not to mention, you'll also be joining a phenomenal crew of colleagues who are smart, engaged and inspiring. We aim high, collaborate hard, and produce results. Let's achieve the impossible together

To round out our world-class total rewards package, we provide annualized base salary compensation in the range listed below. Final salary range may be modified commensurate with job level, education, and experience.

Company Overview

Praxis Precision Medicines is a clinical-stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders characterized by neuronal imbalance. At Praxis we share a common vision of reshaping the human condition into a more freeing and fulfilled existence by developing high impact medicines for patients and families affected by and living with complex brain disorders. Our core Values of Trust, Ownership, Curiosity and Results are foundational to every aspect of our business and are exemplified by each and every one of our team members.

Diversity, Equity & Inclusion

Guided by our core values, at Praxis Precision Medicines, Inc. we continue to DARE FOR MORE to advance, promote, and champion diversity, equity, and inclusion by encouraging individuals to bring their authentic selves and perspectives to work each day. We are an equal opportunity employer and committed to providing opportunities to all qualified applicants without regard to race, religious creed, color, gender identity or expression, age, national origin, sexual orientation, disability, genetics, military service and veteran status, or any other characteristic protected by federal, state, or local laws.

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