Senior Manager, Clinical Scientist

Join Us in Tackling Autoimmune Disease at Its Root
At Vor, we believe science can do more than manage symptoms. It can change the course of disease. By advancing telitacicept, a first- and potentially best-in-class dual BAFF/APRIL inhibitor, we are silencing upstream survival signals and stopping downstream autoimmune cascades. Together, we are addressing disease at its root cause and rewriting what is possible for patients worldwide.

When you join Vor, you're not just working on a medicine. You're part of a mission to redefine the future of autoimmune care.

Why Work at Vor?
Impact: Contribute directly to a medicine with best-in-disease Phase 3 results in myasthenia gravis and expansion into multiple autoimmune diseases.

Growth: Be part of a rapidly scaling company with opportunities to grow your career in science, clinical development, commercial strategy, and beyond.

Innovation: Work on a platform with potential beyond one indication — a therapy that has already shown consistent results across lupus, IgA nephropathy, and Sjögren's syndrome.

Belonging: Join a culture where every voice is heard, and where our shared mission unites us across functions and geographies.

Senior Manager, Clinical Scientist
Overview
The
Senior Manager, Clinical Scientist
plays a pivotal role in supporting global clinical trials by ensuring scientific integrity, data quality, and operational excellence from study design through database lock. This position combines strategic planning with hands-on scientific expertise, serving as a key bridge across clinical departments to drive collaboration and ensure high quality study execution.

Key Responsibilities

• Contributes to preparation and/or review of any documents related to the studies and requiring a scientific background (abbreviated protocol/protocol/amended protocol, informed consent form, presentations/communication to internal or external partners, study plans including medical monitoring plan, safety management plan, risk mitigation plan and recruitment materials).
• Assists in preparing medical answers to questions from Health Authorities, IRB/Ethics Committees, investigators, experts involved in the study/project.
• Contributes to the definition of the critical data/processes/predefined deviations list, risks and Quality tolerance limits identification and monitoring, to implement/develop related sections of the study risk management plan.
• Is involved in the update of study documents, ensures eCRFs are aligned with protocol updates, and contributes to optimizing and documenting data collection processes to enhance quality and reduce complexity.
• Supports Medical Monitors in subject-level data reviews, including eligibility assessments and ongoing data monitoring, ensuring timely data entry, consistency, and integrity.
• Supports data cleaning and query resolution throughout the study and participates in final review activities leading up to database lock to ensure data accuracy and integrity.
• Collaborates with Medical and Clinical Operations teams in developing study-specific training materials and provides scientific support during investigator and study team trainings.
• Contributes to definition of the centralized monitoring strategy in consistency with the planned statistical analysis and is involved in study data validation and review processes, support the director for the Clinical Case review (safety events reported to GPV or safety events of special interest), notably to anticipate and prevent last minute queries or backlog and smoothen the process.

Qualifications

• Education: Advanced degree (PhD, PharmD, MD, or equivalent) in life sciences, medicine, or a related field.
• Experience: Minimum of 6 years in clinical research, with demonstrated leadership in clinical science roles.
• Familiar with digital tools such as data analytics or agility to use them
• Ability to synthesize the information, good presentation skills and effective communication skills (verbal and written)
• Strong knowledge of clinical trial design, methodology, and regulatory requirements.
• Excellent analytical, organizational, and communication skills.
• Ability to manage multiple projects and priorities in a fast-paced environment.
• Proven track record of cross-functional collaboration and team leadership.

Core Competencies

• Strategic Thinking: Ability to anticipate challenges, identify opportunities, and develop innovative solutions.
• Scientific Rigor: Commitment to high-quality research and evidence-based decision-making.
• Leadership: Skilled at motivating teams, mentoring staff, and fostering a culture of excellence.
• Communication: Effective at presenting complex scientific concepts to diverse audiences.

At Vor, we support our team with robust benefits, including comprehensive health coverage, flexible paid time off, generous parental leave, and a competitive 401(k). From education assistance to wellness resources and financial security, we invest in your well-being so you can thrive at work and beyond.

As an equal opportunity employer, we at Vor Bio know that diversity inspires innovation, inclusiveness, and creativity. We invite you to come as you are. All applicants will be considered for employment agnostic to race, age, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.

Please visit our website at for more information.